A5101974399- Protein Hydrolysis and Bioactive Peptides
- Pineapple and bromelain studies
- Regulation of Appetite and Obesity
- Genetic Neurodegenerative Diseases
- Cholesterol and Lipid Metabolism
- Probiotics and Fermented Foods
- Antimicrobial Peptides and Activities
- Meat and Animal Product Quality
- Cellular transport and secretion
- Neuroinflammation and Neurodegeneration Mechanisms
- Circadian rhythm and melatonin
- Tryptophan and brain disorders
- Streptococcal Infections and Treatments
- Neuropeptides and Animal Physiology
- Adenosine and Purinergic Signaling
- Aquaculture disease management and microbiota
- Nanocomposite Films for Food Packaging
- Microbial Inactivation Methods
- Oral microbiology and periodontitis research
- Helicobacter pylori-related gastroenterology studies
- Pancreatic function and diabetes
- Microtubule and mitosis dynamics
- Neuroendocrine regulation and behavior
Daegu Gyeongbuk Institute of Science and Technology
2017-2018
Obesity-associated metabolic alterations are closely linked to low-grade inflammation in peripheral organs, which macrophages play a central role. Using genetic labeling of myeloid lineage cells, we show that hypothalamic normally reside the perivascular area and circumventricular organ median eminence. Chronic consumption high-fat diet (HFD) induces expansion monocyte-derived macrophage pool arcuate nucleus (ARC), is significantly attributed enhanced proliferation macrophages. Notably,...
Dendrite aberration is a common feature of neurodegenerative diseases caused by protein toxicity, but the underlying mechanisms remain largely elusive. Here, we show that nuclear polyglutamine (polyQ) toxicity resulted in defective terminal dendrite elongation accompanied loss Golgi outposts (GOPs) and decreased supply plasma membrane (PM) Drosophila class IV dendritic arborization (da) (C4 da) neurons. mRNA sequencing revealed genes downregulated polyQ proteins included many secretory...
Listeria monocytogenes is a major foodborne pathogen that causes listeriosis and poses potential threats to human health. Ovotransferrin (OT) an egg white protein with many functional properties. In this study, the anti-biofilm effect of OT hydrolysates (OTH) enzymes (bromelain, Flavourzyme®, Neutrase®, papain, Protamex®) against L. was investigated. The OTH prepared bromelain (OTBM), Flavourzyme® (OTFV), papain (OTPP) significantly inhibited biofilm formation strains. OTFV OTPP showed...
This study investigated the immunostimulatory effect of egg yolk-derived phosvitin phosphopeptides (PPPs) prepared by high-temperature and mild-pressure (HTMP) pretreatment enzyme combinations in RAW 264.7 macrophages. Treating macrophages with PPPs, especially those produced HTMP trypsin + Multifect 14L combination (HTMP-TM), significantly increased nitric oxide (NO) production. The PPPs NO production inducing expression inducible synthase (iNOS) mRNA cells. secretion pro-inflammatory...
Ovomucin (OM), which has insoluble fractions is a viscous glycoprotein, found in egg albumin. Enzymatic hydrolysates of OM have water solubility and bioactive properties. This study investigated that the immunostimulatory effects (OMHs) obtained by using various proteolytic enzymes (Alcalase®, bromelain, α-chymotrypsin, Neutrase®, pancreatin, papain, Protamax®, trypsin) RAW 264.7 cells. The results showed OMH prepared with pancreatin (OMPA) produced highest levels NO cells, through...
Streptococcus mutans, the main pathogen associated with tooth decay, forms cariogenic biofilms on surfaces. Therefore, controlling oral biofilm helps prevent dental caries. Hen's egg is a nutrient-dense food, and white good source of protein. Ovomucoid one major proteins in white, 28 kDa molecular weight. The present study aimed to investigate inhibitory effects ovomucoid formation S. mutans by suppressing virulence factors, including bacterial adherence, cellular aggregation...