A5040392835- Genetic diversity and population structure
- Wildlife Ecology and Conservation
- Genomics and Phylogenetic Studies
- Animal Ecology and Behavior Studies
- Genetic and phenotypic traits in livestock
- Evolution and Paleontology Studies
- Genetic Mapping and Diversity in Plants and Animals
- Environmental DNA in Biodiversity Studies
- Chromosomal and Genetic Variations
- Identification and Quantification in Food
- Molecular Biology Techniques and Applications
- Animal Genetics and Reproduction
- Human-Animal Interaction Studies
- Veterinary Medicine and Surgery
- Forensic and Genetic Research
- Primate Behavior and Ecology
- Protein Structure and Dynamics
- Evolution and Genetic Dynamics
- Amphibian and Reptile Biology
- Species Distribution and Climate Change
- Enzyme Structure and Function
- Animal Disease Management and Epidemiology
- Protein Degradation and Inhibitors
- Adipose Tissue and Metabolism
- Cell Image Analysis Techniques
Leibniz Institute for Zoo and Wildlife Research
2012-2023
University of York
2009-2022
Freie Universität Berlin
2005-2017
University of Potsdam
2017
École Pratique des Hautes Études
2017
Sorbonne Université
2017
Institut de Systématique, Évolution, Biodiversité
2017
Centre National de la Recherche Scientifique
2017
Salim Ali Center for Ornithology and Natural History
2017
National Centre for Biological Sciences
2017
Noninvasive genetics based on microsatellite markers has become an indispensable tool for wildlife monitoring and conservation research over the past decades. However, microsatellites have several drawbacks, such as lack of standardisation between laboratories high error rates. Here, we propose alternative single-nucleotide polymorphism (SNP)-based marker system noninvasively collected samples, which promises to solve these problems. Using nanofluidic SNP genotyping technology (Fluidigm),...
By combining high-throughput sequencing with target enrichment ('hybridization capture'), researchers are able to obtain molecular data from genomic regions of interest for projects that otherwise constrained by sample quality (e.g. degraded and contamination-rich samples) or a lack priori sequence information studies on nonmodel species). Despite the use hybridization capture in various fields research many years, impact conditions success is not yet thoroughly understood. We evaluated key...
Determining species distributions can be extremely challenging but is crucial to ecological and conservation research. Environmental DNA (eDNA) approaches have shown particular promise in aquatic systems for several vertebrate invertebrate species. For terrestrial animals, however, eDNA-based surveys are considerably more difficult due the lack of or difficulty obtaining appropriate sampling substrate. In water-limited ecosystem where mammals often forced congregate at waterholes, water...
A selective sweep is the result of strong positive selection driving newly occurring or standing genetic variants to fixation, and can dramatically alter pattern distribution allelic diversity in a population. Population-level sequencing data have enabled discoveries sweeps associated with genes involved recent adaptations many species. In contrast, much debate but little evidence addresses whether “selfish” are capable fixation—thereby leaving signatures identical classical sweeps—despite...
Advances in high-throughput sequencing (HTS) have made it a powerful resource for the conservation of threatened species, providing information at both population and individual levels to inform management decisions. In South America, however, application HTS has been limited, primarily due challenges funding access advanced genomic equipment analytical expertise. Darwin’s fox ( Lycalopex fulvipes ), endemic Chile’s Valdivian Temperate Rainforest, is most endangered canid America with small...
The members of the genus Muntiacus are particular interest to evolutionary biologists due their extreme chromosomal rearrangements and ongoing discussions about number living species. Red muntjacs have largest distribution all were formerly considered as one Karyotype differences led provisional split between Southern Muntjac (Muntiacus muntjak) Northern (M. vaginalis), but uncertainties remain as, so far, no phylogenetic study has been conducted. Here, we analysed whole mitochondrial...
Genetic studies of the Eurasian brown bear (Ursus arctos) have so far focused on populations from Europe and North America, although largest distribution area bears is in Asia. In this study, we reveal population genetic parameters for inhabiting Grand Kaçkar Mountains (GKM) north east Turkey, western Lesser Caucasus. Using both hair (N = 147) tissue samples 7) collected between 2008 2014, found substantial levels variation (10 microsatellite loci). Bear (hair) taken rubbing trees worked...
The Leopard cat Prionailurus bengalensis is a habitat generalist that widely distributed across Southeast Asia. Based on morphological traits, this species has been subdivided into 12 subspecies. Thus far, there have few molecular studies investigating intraspecific variation, and those had limited in geographic scope. For reason, we aimed to study the genetic structure evolutionary history of its very large distribution range We employed both PCR-based (short mtDNA fragments, 94 samples)...
The colonization history of Madeiran house mice was investigated by analysing the complete mitochondrial (mt) D-loop sequences 156 from island Madeira and mainland Portugal, extending on previous studies. numbers mtDNA haplotypes Portugal were substantially increased (17 14 new respectively), phylogenetic analysis confirmed previously reported link between archipelago northern Europe. Sequence revealed presence four lineages in which one particularly common widespread (termed 'Portugal Main...
Over the past ~40 years, several attempts were made to reintroduce Eurasian lynx suitable habitat within their former distribution range in Western Europe. In general, limited numbers of individuals have been released establish new populations. To evaluate effects reintroductions on genetic status populations we used 12 microsatellite loci study Bohemian–Bavarian and Vosges–Palatinian forests. Compared with autochthonous populations, these two reintroduced displayed reduced diversity,...
Abstract Targeted capture coupled with high‐throughput sequencing can be used to gain information about nuclear sequence variation at hundreds thousands of loci. Divergent reference makes use molecular data one species enrich target loci in other (related) species. This is particularly valuable for nonmodel organisms, which often no a priori knowledge exists regarding these Here, we have targeted obtain 809 coding DNA sequences ( CDS ) organism, the Eurasian lynx Lynx , using baits designed...
The phylogeographic architecture of the common vole, Microtus arvalis, has been well-studied using mitochondrial DNA and used to test hypotheses relating glacial refugia. distribution five described cytochrome b (cyt b) lineages in Europe west Russia interpreted as a consequence postglacial expansion from both southern central European A recently proposed competing model suggests that ‘cradle’ M. arvalis is western where they dispersed different directions after Last Glacial Maximum. In...
Resolving the historical biogeography of leopard (Panthera pardus) is a complex issue, because patterns inferred from fossils and molecular data lack congruence. Fossil evidence supports an African origin, suggests that leopards were already present in Eurasia during Early Pleistocene. Analysis DNA sequences however, more recent, Middle Pleistocene shared ancestry Asian leopards. These contrasting led researchers to propose two-stage hypothesis dispersal out Africa: initial colonisation Asia...
The Caucasian lynx, Lynx lynx dinniki, has one of the southernmost distributions in Eurasian range, covering Anatolian Turkey, Caucasus and Iran. Little is known about biology genetic status this subspecies. To collect baseline genetic, ecological behavioural data benefit future conservation L. l. we monitored 11 territories (396 km2) northwestern Anatolia. We assessed diversity population by non-invasively collecting 171 faecal samples trapped sampled 12 individuals using box traps....
The sun bear
Background. The bay cat Catopuma badia is endemic to Borneo, whereas its sister species the Asian golden temminckii distributed from Himalayas and southern China through Indochina, Peninsular Malaysia Sumatra. Based on morphological data, up five subspecies of have been recognized, but a taxonomic assessment, including molecular data characters, still lacking. Results. We combined (whole mitochondrial genomes), (pelage) distribution projections (up Late Pleistocene) infer how environmental...
The first natural chromosomal variation in the house mouse was described nearly 50 years ago Val Poschiavo on Swiss side of Swiss–Italian border Central Eastern Alps. Studies have extended into neighboring Valtellina, and mice Poschiavo-Valtellina area been subject to detailed analysis, reviewed here. maximum extent this is 70 km, yet it has 4 metacentric races standard 40-chromosome telocentric race distributed a patchwork fashion. are characterized by highly reduced diploid numbers (2n =...
Abstract Species of the mustelid subfamily Guloninae inhabit diverse habitats on multiple continents, and occupy a variety ecological niches. They differ in feeding ecologies, reproductive strategies morphological adaptations. To identify candidate loci associated with adaptations to their respective environments, we generated de novo assembly tayra ( Eira barbara ), earliest diverging species subfamily, compared this genomes available for wolverine Gulo gulo ) sable Martes zibellina ). Our...
Previous molecular studies of the wide-ranging Eurasian lynx Lynx focused mainly on its northern Palearctic populations, with consequence that reconstruction this species’ evolutionary history did not include genetic variation present in southern distribution. We sampled a previously considered Asian subspecies (L. l. dinniki), added published data from another isabellinus), and reassessed mtDNA phylogeny along populations. Our mitogenome-based analyses revealed existence three major clades...
Abstract Conservation genetics can provide data needed by conservation practitioners for their decisions regarding the management of vulnerable or endangered species, such as sun bear Helarctos malayanus . Throughout its range, is threatened loss and fragmentation habitat illegal trade both live bears parts. Sharply declining population numbers sizes, a lack natural dispersal between populations all threaten genetic diversity remaining this species. In first study using microsatellite...
In the house mouse there are numerous chromosomal races distinguished by different combinations of metacentric chromosomes. These may come into contact with each other and ancestral all-acrocentric race, form hybrid zones. The clines that make up these zones be coincident or separated from (staggered). Such staggered interesting because they include populations individuals homozygous for a mix features hybridising races. We review characteristics four in discuss whether examples primary...