A5049352728- Neuroscience and Neuropharmacology Research
- Mitochondrial Function and Pathology
- Circadian rhythm and melatonin
- Adipose Tissue and Metabolism
- Genetics and Neurodevelopmental Disorders
- Photoreceptor and optogenetics research
- Sleep and Wakefulness Research
Instytut Biologii Doświadczalnej im. Marcelego Nenckiego
2024-2025
Polish Academy of Sciences
2024-2025
Swansea University
2024
Imperial College London
2015
This research aims to reveal fundamental mechanisms of neurodegenerative disorders by studying the consequences disrupted lipid homeostasis in neurons means functional synapse assays and protein expression analyses. In neurodegeneration, physiology synapses is altered. Here, plasmalogen lipids are abundant their peculiar conical shape makes them ideal supporting vesicle fusion. addition, levels decrease with pathological progression Alzheimer’s disease. Since current evidence correlative, we...
Abstract Our previous in silico data indicated an overrepresentation of the ZF5 motif promoters genes which circadian oscillations are altered ventral hippocampus pilocarpine model temporal lobe epilepsy mice. In this study, we test hypothesis that Zbtb14 protein oscillates a manner and oscillation is disrupted by epilepsy. We found immunostaining present cytoplasm cell nuclei. Western blot indicate cytoplasmic nuclear levels oscillate, but phase shifted. The densities Zbtb14-immunopositive...