A5063163657- Neuroscience and Neuropharmacology Research
- Ion Transport and Channel Regulation
- Barrier Structure and Function Studies
- Homelessness and Social Issues
- Cerebrovascular and Carotid Artery Diseases
- Parathyroid Disorders and Treatments
- Pleural and Pulmonary Diseases
- Intracranial Aneurysms: Treatment and Complications
- Pneumocystis jirovecii pneumonia detection and treatment
- Antifungal resistance and susceptibility
- Pancreatic function and diabetes
- Occupational and environmental lung diseases
- Fungal Infections and Studies
- Infant Health and Development
- Gastric Cancer Management and Outcomes
- Anorectal Disease Treatments and Outcomes
- Drug Transport and Resistance Mechanisms
- Gastrointestinal disorders and treatments
- Diabetes and associated disorders
- Colorectal Cancer Surgical Treatments
- Pediatric health and respiratory diseases
- Muscle and Compartmental Disorders
- Surgical site infection prevention
- Neuroinflammation and Neurodegeneration Mechanisms
- Neuroendocrine regulation and behavior
San Joaquin General Hospital
2013-2023
University of South Florida
2022
Regional Medical Center
2022
St. George's University
2022
University of California, Davis
2005-2017
Introduction: Parathyroid carcinoma (PC) is an extremely rare entity, with a frequency of 0.005% all malignancies. Most data related to this disease are limited case series and few database studies. We present large study that aims investigate the demographic, clinical, pathological factors, prognosis, survival PC. Methods: Data parathyroid were extracted from Surveillance, Epidemiology, End Results (SEER) diagnosed between 1975 2016. Results: PC had slightly higher incidence in men (52.2%,...
Introduction: Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasm of gastrointestinal (GI) system. Most GISTs originate from interstitial cells Cajal (ICC), pacemaker cell situated between circular and longitudinal layers muscularis propria along GI tract. In this population-based study using SEER database, we sought to identify demographic, clinical, pathologic factors that affect prognosis survival patients with neoplasm. Molecular genetic advances, current...
Estrogen has been shown to protect against stroke-induced brain damage, yet the mechanism is unknown. During early hours of stroke, cerebral edema forms as increased transport Na and Cl from blood into occurs across an intact blood–brain barrier (BBB). We showed previously that a luminal BBB Na–K–Cl cotransporter stimulated by hypoxia arginine vasopressin (AVP), factors present during ischemia, inhibition intravenous bumetanide greatly reduces in rats subjected permanent middle artery...
Brain edema that forms during the early stages of stroke involves increased transport Na + and Cl − across an intact blood-brain barrier (BBB). Our previous studies have shown a luminal BBB -K -Cl cotransporter is stimulated by conditions present ischemia inhibition intravenous bumetanide greatly reduces formation in rat middle cerebral artery occlusion model stroke. The study focused on investigating effects hypoxia, which develops rapidly brain ischemia, activity expression cotransporter,...
Ischemia-induced brain edema formation is mediated by increased transport of Na and Cl across an intact blood-brain barrier (BBB). Our previous studies have provided evidence that a luminally located BBB Na-K-Cl cotransporter stimulated during cerebral ischemia to increase into the brain. The main focus present study was evaluate effects arginine vasopressin (AVP), previously shown be in promote formation, on activity cotransporter. Cerebral microvascular endothelial cell (CMEC) monolayers...
Increased transport of Na across an intact blood-brain barrier (BBB) contributes to cerebral edema formation in ischemic stroke. Our previous studies have shown that factors stimulate activity a luminal BBB Na-K-Cl cotransporter, and we hypothesized during ischemia, the cotransporter together with abluminal Na/K pump mediates increased from blood into brain. However, it is possible elevated could also cause cell swelling if outpaces ion efflux pathways. The present study was conducted...
Increased blood-brain barrier (BBB) Na-K-Cl cotransporter activity appears to contribute cerebral edema formation during ischemic stroke. We have shown previously that inhibition of BBB reduces and infarct in the rat middle artery occlusion (MCAO) model also is stimulated by factors hypoxia, aglycemia, arginine vasopressin (AVP), although mechanisms responsible are not well understood. AMP-activated protein kinase (AMPK), a key mediator cell responses stress, can be activated variety...
Depending on the host's immunological and respiratory systems, Aspergillus can induce infectious allergic diseases. Most of spread occurs in immunocompromised people, whereas aggressive disorder immunocompetent patients is unusual. We report case a 19-year-old female who had shortness breath, right-sided chest discomfort, intermittent hemoptysis for six months before being diagnosed with pulmonary aspergilloma. The initial x-ray revealed massive right pneumothorax 7.2 cm rounded opacity...
Increased blood‐brain barrier (BBB) Na‐K‐Cl cotransporter activity appears to contribute cerebral edema formation during ischemic stroke. The is stimulated by hypoxia and aglycemia, although the mechanisms responsible are unknown. Inhibition of p38MAP kinase (p38MAPK), which activated ischemia, has been found reduce brain infarct in In present study we examined possibility that p38MAPK participates ischemia‐induced stimulation BBB cotransporter. Cerebral microvascular endothelial cells...
Mesotheliomas are a rare malignancy of the serosal membrane. Mainly it affects pleural surfaces followed by second most common location, "peritoneum." The disease follows an aggressive pattern spread, and time diagnosis is established, condition significantly spreads to distant locations. Diagnosis malignant peritoneal mesothelioma typically made tissue biopsy. standard treatment radical resection; however, patients have benefited from several other modalities. current case report describes...