A5050715164- Reproductive System and Pregnancy
- Preterm Birth and Chorioamnionitis
- Pregnancy-related medical research
- Pregnancy and preeclampsia studies
- Neonatal Respiratory Health Research
- Reproductive tract infections research
- Birth, Development, and Health
- Pregnancy and Medication Impact
- Cancer Risks and Factors
- Assisted Reproductive Technology and Twin Pregnancy
- Pelvic floor disorders treatments
- Ectopic Pregnancy Diagnosis and Management
- Nutrition and Health Studies
- Gestational Diabetes Research and Management
- Reproductive Physiology in Livestock
- Air Quality and Health Impacts
- Labour Market and Migration
- Endometriosis Research and Treatment
- Urinary Tract Infections Management
- interferon and immune responses
- COVID-19 Impact on Reproduction
- Reproductive Health and Contraception
- Maternal and Perinatal Health Interventions
- Congenital Diaphragmatic Hernia Studies
- Urological Disorders and Treatments
Medical University of Lodz
2013-2024
Wojewódzki Szpital Specjalistyczny Nr 2
2016
Nofer Institute of Occupational Medicine
2008
GTx (United States)
2005
Instytut Matki i Dziecka
1999-2003
BackgroundThere is a growing body of epidemiologic literature reporting associations between atmospheric pollutants and reproductive outcomes, particularly birth weight gestational duration.ObjectivesThe objectives our international workshop were to discuss the current evidence, identify strengths weaknesses published studies, suggest future directions for research.DiscussionParticipants identified promising exposure assessment tools, including models with fine spatial temporal resolution...
Problem: The therapeutic value of progestogens in threatened abortion is still under debate. In the presence sufficient progesterone levels during pregnancy, lymphocytes synthesize a mediator [progesterone‐induced blocking factor (PIBF)] that anti‐abortive mice. aim this study was to evaluate effect dydrogesterone on pregnancy outcome aborters. Method Study: Twenty‐seven aborters were treated for 10 days with (30–40 mg/day). Sixteen healthy pregnant controls received no treatment. Serum and...
The aim of the study was to analyse a panel 11 sphingolipids in plasma and three blood fractions (platelet-poor plasma, platelets red cells) women with mild preeclampsia.We recruited 21 between 25-40 weeks gestation diagnosed preeclampsia group 36 healthy uncomplicated pregnancies, who corresponded according gestational age, control group. To assess concentration fractions, we used ultra-high performance liquid chromatography coupled triple quadrupole mass spectrometry (UHPLC/MS/MS).We...
Problem The initiation of labor is accompanied by alterations in the level maternal immune tolerance toward fetal antigens. It a complex molecular response leading to brief activation system with an accompanying capacity restrict this same activation. aim our study was evaluate subpopulation regulatory T cells (Tregs) and B7‐H4 macrophages decidua basalis during cesarean sections performed on patients various stages labor. Method decidual tissue samples evaluated were obtained from 23...
Problem The main aim of this study was to investigate the relationship between selected proinflammatory cytokines [interleukin IL‐1 alpha (IL‐1 α ), beta β IL‐6 and IL‐8] concentrations in cervicovaginal fluid, as measured midgestation, risk subsequent preterm delivery. Method Cervicovaginal fluids were obtained from a cohort 114 pregnant women at 22–34 weeks’ gestation analyzed for , IL‐8 using enzyme‐linked immunosorbent assay technique. Lower genital tract microbiology diagnosed Gram...
Aim of this project is determination the correlation between level vitamin D in blood serum and duration pregnancy population central Poland.25-Hydroxyvitamin (25(OH)D) was determined serum, using enzyme-linked immunosorbent assay (ELISA). Standardized history each patient recorded. The included: general medical history, data regarding course information about health-related behavior that could influence concentration. Two hundred-and-one Caucasian women at childbirth were qualified into...
The recommendations present current methods of treatment that may be subject to modification and change in justified cases, after careful analysis the given clinical situation.In future, this basis for their updating.
1. The present investigation was undertaken to evaluate the effect of environmental tobacco smoke (ETS) on risk preterm delivery (PD) and small-for-gestational age (SGA) infants in a female non-smoking population central Poland. 2. study group were 1751 women classified as non-smokers comprehensive project 'Socio-economic factors small-for-gestationaI-age babies Poland' conducted randomly selected 2080 who gave birth child between June 1, 1996 May 31, 1997. PD comprised 95 delivered before...
The aim of this prospective cohort study was to evaluate the impact tobacco smoke exposure, measured by maternal serum concentration cotinine, on fetal midgestation biometric parameters and umbilical artery (UA) qualitative blood flow indices. population consisted 114 healthy women in 20 24 weeks gestation who were recruited from patients two antenatal care units Lodz, Poland. Significant negative correlation found between biparietal diameter (BPD) cotinine concentration. Serum positively...
Our previous study revealed that anti-inflammatory cytokine gene polymorphisms increase the risk of spontaneous preterm delivery (PD) in a population Polish women. Different genetic background PD due to premature rupture membranes (pPROM) than without pPROM has been suggested. The aim this was examine relationship between maternal carriage polymorphic alleles following genes: interleukin 1β(IL-1β [+3953C>T]), 6 promoter (IL-6 [-174G>C]), tumour necrosis factor (TNF-α [-308G>A]) and 1...
Unemployment is one of the consequences ongoing transformation Polish economy. The main objective present study was to investigate relationship between women's employment status and preterm delivery (PD) and/or small-for-gestational-age (SGA) infants, in Central Poland during socio-economic transition.The population comprised 8% random sample 2,080 women from Lodz macro region who gave birth a child one-year period (1996-1997). Based on status, three groups were distinguished: employed (n =...
Ficolin-2 is a serum pattern recognition molecule, involved in complement activation via the lectin pathway. This study aimed to investigate association of ficolin-2 concentration cord blood with complications related premature birth.546 neonates were included. The was determined by sandwich TRIFMA method. FCN2 genetic variants analysed RFLP-PCR, allele-specific PCR, Sanger sequencing or allelic discrimination using TaqMan probes method.Cord correlated positively Apgar score and inversely...
The following Guidelines present the most up-to-date treatment and management recommendations, which may be modified altered after detailed analysis of a specific clinical situation, in turn might lead to future modifications updates.
Objectives: Vitamin D receptor (VDR) is expressed in the placenta and tissues related to immune system occurrence of various variants VDR may modify effects vitamin on pregnancy. The aim this study was evaluate association between parturients' Apa1, Taq1, Bsm1 polymorphisms their combinations risk preterm birth Polish population. Material methods: Determination polymorphism for assayed using RT-PCR method. 199 Caucasian women at childbirth were qualified:100 patients who had a spontaneous 99...
Background Heavy physical work is still considered one of the most prevalent risk factors negative pregnancy outcome. The present study was undertaken to evaluate impact heavy during pregnancy, based on subjective assessment workload, delivering a small-for-gestational-age (SGA) baby. Methods Job characteristics were compiled for 1,064 working women from Łódź region (8% population sample) questionnaire responses. Energy expenditure daily estimated. SGA diagnosed when birth weight below 10th...
Problem Bacteria activates Toll‐like receptor 4 on immune system cells leading to preterm birth ( PTB ). The aim of study was evaluate the impact maternal and fetal carriage TLR gene polymorphisms risk . Method Study Frequency (896A>G, 1196C>T) variants determined in 121 women who delivered preterm, 152 at term, 49 term newborns 35 with use PCR ‐ RFLP Results We found no associations between frequency polymorphic alleles mothers fetuses delivery before 37th week pregnancy. However...
The aim of the study was to estimate relationship between bladder neck hypermobility as assessed by ultrasound and occurrence stress urinary incontinence measured with UDI-6 questionnaire in primiparous women 9-18 months postpartum.
Being unmarried is a well-known risk factor for poor pregnancy outcome such as preterm delivery and intrauterine growth restriction. The aim of this prospective study was to assess the prevalence bacterial vaginosis (BV) selected bacteria isolated from lower genital tract determine socioeconomic microbiological characteristics that might be responsible observed among pregnant women.The population comprised 196 women attending 10 randomly outpatient maternity units in Lodz region, central...