A5103164397- Pregnancy and preeclampsia studies
- Assisted Reproductive Technology and Twin Pregnancy
- Pregnancy-related medical research
- Maternal and fetal healthcare
- Maternal and Perinatal Health Interventions
- Ectopic Pregnancy Diagnosis and Management
- Cancer Risks and Factors
- Preterm Birth and Chorioamnionitis
- Labour Market and Migration
- Nutrition and Health Studies
- Pelvic floor disorders treatments
- Ovarian cancer diagnosis and treatment
- Prenatal Screening and Diagnostics
- Gestational Diabetes Research and Management
- Urinary and Genital Oncology Studies
- Birth, Development, and Health
- Uterine Myomas and Treatments
- Glycosylation and Glycoproteins Research
- Pelvic and Acetabular Injuries
- Congenital Diaphragmatic Hernia Studies
- Neonatal Respiratory Health Research
- COVID-19 and healthcare impacts
- Child and Adolescent Health
- Endometriosis Research and Treatment
- Gynecological conditions and treatments
Wroclaw Medical University
2015-2024
University Hospital Bonn
2024
University of Wrocław
2013-2022
Wroclaw University of Environmental and Life Sciences
2020
Szpital Kliniczny Nr 1 we Wrocławiu
2019-2020
Nicolaus Copernicus University
2020
Westpfalz Klinikum
2018-2019
Develco Pharma (Switzerland)
2017
Medical University of Warsaw
2016
World Water Watch
2011
The human neutrophil and monocyte-derived serine protease homologues elastase (NE), proteinase 3 (PR3), azurocidin (AZU) are involved in a variety of immune defense reactions. NE PR3 assist the destruction phagocytosed microorganisms, cleave important connective-tissue protein elastin, generate chemotactic activities by forming alpha 1-proteinase inhibitor complexes elastin peptides. AZU is cytotoxic to certain microorganisms for monocytes. All three proteins produced packaged into azurophil...
A glutaminyl cyclase (QC) that is probably involved in the biosynthesis of pyroglutamyl peptides such as gonadotropin-releasing hormone and thyrotropin-releasing has been purified to homogeneity from bovine anterior pituitary. On basis N-terminal sequence analysis, a 2088-base-pair cDNA clone was isolated pituitary library. From nucleotide this clone, primary structure 330-residue protein preceding 31-residue prepropeptide deduced. By transfection COS-7 monkey cells with QC cDNA/pCDM8 vector...
To evaluate the differences in placental vascular indices and volume between normal IUGR pregnancies.A prospective study was conducted on a group of 100 20 pregnancies 22 42 weeks gestation. For purpose evaluation indices, we applied 3D Power Doppler VOCAL technique. Only patients with entirely visualized placenta were included study.A comparative analysis vascularization index (VI), flow (VFI), (FI), (PV) revealed statistically significant pregnancies. In pregnancies, average 92.42 cm(3)...
Every year 1.5 million cesarean section procedures are performed worldwide. As many women decide to get pregnant again, the population of with a history is growing rapidly. For these prediction scar performance still serious clinical problem.Starting in 2005, study included 308 nonpregnant low transverse section. The following ultrasonographic parameters uterus were assessed: residual myometrial thickness (RMT) and width (W) depth (D) triangular hypoechoic niche. During 8 years follow-up, 41...
Objectives: The ultrasound-guided transversus abdominis plane (TAP) block is a supporting method of pain relief after different types surgical and gynecological procedures. aim the present study was to evaluate analgesic effects TAP-block in patients undergoing caesarean section. Material methods: 88 women elective section under spinal anaesthesia were prospectively randomized into two groups. In first group, an bilateral TAP performed using 40 mL 0.25% bupivacaine, while second group...
In recent years, the worldwide percentage of deliveries by caesarean section has increased. However, this only improved obstetric outcomes in low-income countries [1, 2]. Unfortunately, Poland and other high-income countries, rate section, which is greater than 20%, no longer associated with decreases perinatal mortality mothers their offspring. Currently Poland, 43.85% births are [3]. The increased number sections may be development medicine, diagnostics particular, can have an impact on...
The recommendations present the current state of knowledge on presented subject day publication.The board experts reserves right to update information in case new significant scientific reports.The undertook analysis literature, expert and clinical experience matters
Volume regulation of C6 glial cells was studied in anoxia vitro to improve the understanding ischemic cell swelling brain. Contrary vivo conditions, or plus iodoacetate for additional inhibition anaerobic energy metabolism did not induce swelling. However, intracellular K+ markedly decreased while Na+ increased. Induction failure by found prevent regulatory volume decrease on hyposmotic exposure cells, which is regularly observed normoxic control conditions. Hyposmotic led only an initial...
Objectives: A growing number of studies suggest that the incomplete healing CS scar in uterus increase risk uterine dehiscence or rupture during subsequent pregnancies. Thus, factors affect wound should be evaluated. We aimed to determine whether morphology non-pregnant women after one elective was affected by site incision, flexion, maternal age, and fetal birth weight. Material methods: 208 were invited for participation study, but only 101 them met inclusion criteria. Standardized...
The Polish Society of Colposcopy and Cervical Pathophysiology (PTKiPSM) together with the Gynecologists Obstetricians (PTGiP) issued a final summary interim guidelines for secondary cervical cancer prevention during SARS-CoV-2 pandemic based on analysis latest directional publications authors' own experiences. aim is to facilitate implementation most effective possible screening precancerous lesions due temporary significant limitation as consequence ongoing epidemiological threat. These are...
The rising global incidence of cervical cancer is estimated to have affected more than 600,000 women, and nearly 350,000 women are predicted died from the disease in 2020 alone. Novel advances prevention, screening, diagnosis treatment all but reduced burden developed nations. Unfortunately, still number one gynecological globally. A limiting factor managing globally access healthcare systems trained medical personnel. Any methodology or procedure that may simplify assist screening...
Three cDNA clones, pHGR122, pHGR11, and pHGR74 containing the coding information for abundant mRNAs were identified from a human ovarian granulosa cell library. Characterization by nucleotide sequencing revealed that pHGR122 was specific collagenase inhibitor pHGR11 melanoma-associated antigen ME491. Relative quantification Northern analysis indicated mRNA is major species in cells. This finding provides evidence origin of this protein follicular fluid as secretory product ME491 unexpected...
The study aimed at determining whether there exists a correlation between the cervical cohesion parameters assessed in elastography and length of cervix.Assessment with use real-time sonoelastography was performed on 59 patients 28 39 weeks gestation.The analysis showed that statistically significant (p=0.033) elasticity front labium (strain ratio A). Correlation coefficient (r) stood (-) 0.28.1. There negative condition elastographic imaging canal USG imaging. 2. Elastography uterine cervix...
Fucose, the monosaccharide frequent in N- and O-glycans, is a part of Lewis-type antigens that are known to mediate direct sperm binding zona pellucida. Such interaction was found be inhibited vitroby fucose-containing oligo- polysaccharides, as well neoglycoproteins. The objective this study screen seminal plasma proteins infertile/subfertile men for content density fucosylated glycoepitopes, compare them samples fertile normozoospermic subjects. Seminal were separated polyacrylamide gel...
Carbohydrates are known to mediate some events involved in successful fertilization. Although studies on the glycosylation of seminal plasma proteins available, total glycan profile was rarely analyzed as a feature influencing fertilization potential. In this work we aimed compare traits glycoproteins fertile and infertile men. The following findings emerge from our studies: (1) human presence alterations O-linked glycans were observed; (2) expression SNA-reactive sialic acid significantly...
The recommendations present current methods of treatment that may be subject to modification and change in justified cases, after careful analysis the given clinical situation.In future, this basis for their updating.
The aim of the study was to assess clinical outcomes surgical repair uterine cesarean scar defects with sonography (US).Seven nonpregnant women history section and a large defect were enrolled. performed by minilaparotomy. US assessment using standardized approach at baseline, then first visit 2-3 days following intervention (V1) follow-up 3 months later (V2). Residual myometrial thickness (RMT), width, depth measured.The mean RMT increased significantly from 1.9 mm baseline 8.8 V1 8.0 V2....
The expression and activity of matrix metalloproteinases (MMPs) may be regulated by oxidative stress in various pathophysiological processes; therefore, the aim present study was to analyse associations between gelatinases MMP-9 MMP-2 their tissue inhibitors TIMP-1, TIMP-2 levels total antioxidant capacity (TAC) advanced oxidation protein products (AOPP) seminal plasma prepared for artificial insemination. Levels MMPs TIMPs were evaluated using ELISA, whereas TAC AOPP 131 childless men 38...