A5062235241- Corneal Surgery and Treatments
- Corneal surgery and disorders
- Graphene and Nanomaterials Applications
- Biomedical Research and Pathophysiology
- RNA modifications and cancer
- Genetic Mapping and Diversity in Plants and Animals
- Andrographolide Research and Applications
- Biometric Identification and Security
- DNA and Biological Computing
- Testicular diseases and treatments
- Nanoparticles: synthesis and applications
- Wound Healing and Treatments
- Natural Compounds in Disease Treatment
- Genomic variations and chromosomal abnormalities
- Gene expression and cancer classification
- Ocular Surface and Contact Lens
- Carbon and Quantum Dots Applications
- Ion Transport and Channel Regulation
- Algorithms and Data Compression
- Genomics and Chromatin Dynamics
- RNA and protein synthesis mechanisms
- Connexins and lens biology
University of California, Davis
1989-2023
Sequences within the spacer region of yeast rRNA cistrons stimulate synthesis major 35S precursor in vivo 10- to 30-fold (E. A. Elion and J. R. Warner, Cell 39:663-673, 1984). Spacer sequences that mediate this stimulatory activity are located approximately 2.2 kilobases upstream from encode 5' terminus precursor. By utilizing a centromere-containing plasmid carrying minigene, 160-base-pair rDNA was identified by deletion mapping is required for efficient stimulation vivo. A 22-base-pair...
Corneal wound healing is integral for resolution of corneal disease or post-operative healing. However, scarring that may occur secondary to this process can significantly impair vision. Tissue transglutaminase 2 (TGM2) inhibition has shown promising antifibrotic effects and thus holds promise prevent treat scarring. The commercially available ocular solution treatment manifestations Cystinosis, Cystaran®, contains the TGM2 inhibitor cysteamine hydrochloride (CH). purpose study assess safety...
Outdoor location-based services (LBS) not only provide convenience in daily life, but also requires location information that operates real time and has high accuracy availability for stable rescue activities of rescuers rescuers, especially emergency situations. Global Positioning System (GPS) or Navigation Satellite (GNSS) an accurate reliable localization performance under line sights wireless environments. But there remains a problem signals cannot be received indoors densely populated...
Purpose: Corneal keratocyte-fibroblast-myofibroblast (KFM) transformation plays a critical role in corneal stromal wound healing. However, the impact of engineered nanomaterials (ENMs), found an increasing number commercial products, on this process is poorly studied. This study investigates effects metal oxide ENMs KFM vitro and vivo. Methods: Cell viability rabbit fibroblasts (RCFs) was tested following treatment with 11 at concentrations 0.5 to 250 µg/ml for 24 hours. Messenger RNA (mRNA)...
Corneal opacification due to fibrosis is a leading cause of blindness worldwide. Fibrosis occurs from many causes including trauma, photorefractive surgery, microbial keratitis (infection the cornea), and chemical burns, yet there paucity therapeutics prevent or treat corneal fibrosis. This study aimed determine if andrographolide, labdane diterpenoid found in Andrographis paniculate, has anti-fibrotic properties. Furthermore, we evaluated andrographolide could differentiation fibroblasts...
Microarrays for genomic analysis pose a rather serious challenge statistical inference on the quality of data. With ability to attach large fragments array substrate, it is now possible search chromosomal imbalances related various diseases at significantly improved resolution. The lies in understanding experimental characteristics and modeling erroneous noise analyze interpret This paper presents method that addresses issues background noise, dye non-linearities, normalization, replicate...