Kara N. Jaeschke

ORCID: 0000-0002-6977-1781
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About
Contact & Profiles
Research Areas
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Vitamin D Research Studies
  • Reproductive Physiology in Livestock
  • Schizophrenia research and treatment
  • Bipolar Disorder and Treatment
  • Mental Health Treatment and Access
  • Diet and metabolism studies
  • Plant biochemistry and biosynthesis
  • Growth Hormone and Insulin-like Growth Factors
  • Traditional and Medicinal Uses of Annonaceae
  • Stress Responses and Cortisol
  • Synthesis and Characterization of Pyrroles
  • Vitamin C and Antioxidants Research

The University of Queensland
2019-2021

Park Centre for Mental Health
2021

Queensland Centre for Mental Health Research
2021

Freie Universität Berlin
2007

The study estimated service coverage for severe mental disorders (psychosis, bipolar disorder and moderate-severe depression), globally regionally, using data collected from the Mental Health Atlas 2017.Service was defined as proportion of people with a contacting health among those to have during 12-month period. We drew upon utilisation 2017. Expected prevalent cases individual were disorder-specific prevalence rate estimates Global Burden Disease Study 2016 total population sizes. Methods...

10.1017/gmh.2021.19 article EN cc-by-nc-nd Cambridge Prisms Global Mental Health 2021-01-01

Abstract Cubane was recently validated as a phenyl ring (bio)isostere, but highly strained caged carbocyclic systems lack π character, which is often critical for mediating key biological interactions. This electronic property restriction associated with cubane has been addressed herein cyclooctatetraene (COT), using known pharmaceutical and agrochemical compounds templates. COT either outperformed or matched in multiple cases suggesting that versatile complementarity exists between the two...

10.1002/chem.201806277 article EN Chemistry - A European Journal 2019-01-25

It is well established that vitamin D essential in calcium homeostasis and bone metabolism. Recent evidence has exposed further roles of adult brain function, specifically indicating low levels during adulthood may be related to cognitive impairment. We have recently shown (AVD) deficiency disrupts hippocampal-dependent learning structural connectivity BALB/c mice. The mouse strain more vulnerable social stress compared with other resilient strains, such as C57BL/6J Therefore, the primary...

10.20900/jpbs.20190008 article EN Journal of Psychiatry and Brain Science 2019-01-01

The quality of the transition period determines lactation dairy cows and its profitability. In early over 90% are in a negative energy balance (NEB). NEB has peak first four weeks postpartum is associated with major alterations growth hormone, insulin-like factor (GH-IGF) axis. catabolic situation leads to GH resistance hepatic tissue because liver receptors down regulated cows. cattle characterized by elevated blood concentrations while insulin regulated. A low IGF-1 concentration serum...

10.21423/aabppro20074636 article EN cc-by American Association of Bovine Practitioners Conference Proceedings 2007-09-20

Major endocrine and metabolic changes occur around parturition the onset of lactation in dairy cows. These influence milk production reproductive performance next lactation. Results this study describe inter-relationships between concentration IGF-1 serum postpartum period yield, parameters (i.e. BHBA, NEFA, urea, bilirubin) body condition as measured by back fat thickness (BFT).

10.21423/aabppro20074635 article EN cc-by American Association of Bovine Practitioners Conference Proceedings 2007-09-20

Abstract Epidemiological and rodent studies suggest an association between vitamin D deficiency brain disorders. To date, many mechanisms have been proposed to explain the role of on function. However, no causal relationship a specific disorder has established. It is plausible that exposure additional insult alters vulnerability deficiency. our knowledge, limited number combined second-hit (e.g. inflammation) with adult (AVD) examine outcomes. This review summarized impact multiple exposures...

10.1079/pavsnnr201712040 article EN CABI Reviews 2018-01-24
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