A5029851209- Vitamin D Research Studies
- Stress Responses and Cortisol
- Diet and metabolism studies
- Tryptophan and brain disorders
- Electrolyte and hormonal disorders
- Vitamin C and Antioxidants Research
- Neuroendocrine regulation and behavior
- Nerve injury and regeneration
- Animal testing and alternatives
- Calcium signaling and nucleotide metabolism
- RNA Interference and Gene Delivery
- Neurogenesis and neuroplasticity mechanisms
- Inflammasome and immune disorders
- Birth, Development, and Health
- Regulation of Appetite and Obesity
- Pharmacological Effects and Toxicity Studies
- Biotin and Related Studies
Queensland Eye Institute
2023
The University of Queensland
2012-2022
Mater Research
2019
Queensland Centre for Mental Health Research
2013-2017
Park Centre for Mental Health
2013-2017
There is increasing evidence from epidemiological studies indicating that vitamin D deficiency during adulthood associated with adverse brain outcomes in humans (Ginde et al., 2009) and rodents (Groves 2014), however, a causal relationship has not yet been established. We have previously shown mouse model impacts on range of functions 2013) should therefore be considered as biologically plausible risk factor for the development neuropsychiatric neurodegenerative disorders. Vitamin known to...
Epidemiological studies have shown that up to one third of adults insufficient levels vitamin D and there is an association between low concentrations adverse brain outcomes, such as depression. Vitamin has been be involved in processes associated with neurogenesis during development. Therefore, the aim this study was test hypothesis adult (AVD) deficiency BALB/c mice (a) hippocampal at baseline, b) following 6 weeks voluntary wheel running (c) a depressive-like phenotype on forced swim...
Abstract Brain‐derived neurotrophic factor (BDNF) signaling plays a major role in the regulation of hippocampal neurogenesis adult brain. While majority studies suggest that this is due to its effect on survival and differentiation newborn neurons, it remains unclear whether directly regulates neural precursor cell (NPC) activity which two receptors, TrkB or p75 neurotrophin receptor (p75 NTR ) mediates effect. Here, we examined both RNA protein expression these receptors found but not are...
It is well established that vitamin D essential in calcium homeostasis and bone metabolism. Recent evidence has exposed further roles of adult brain function, specifically indicating low levels during adulthood may be related to cognitive impairment. We have recently shown (AVD) deficiency disrupts hippocampal-dependent learning structural connectivity BALB/c mice. The mouse strain more vulnerable social stress compared with other resilient strains, such as C57BL/6J Therefore, the primary...