A5070246046- Pancreatitis Pathology and Treatment
- Pancreatic and Hepatic Oncology Research
- Lung Cancer Research Studies
- COVID-19 Clinical Research Studies
- Neuroendocrine Tumor Research Advances
- Immune cells in cancer
- Gallbladder and Bile Duct Disorders
- Noise Effects and Management
- Inflammatory Bowel Disease
- IL-33, ST2, and ILC Pathways
- Mycobacterium research and diagnosis
- Pediatric Hepatobiliary Diseases and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Apelin-related biomedical research
- Heavy Metal Exposure and Toxicity
- Air Quality and Health Impacts
- Immune Response and Inflammation
- Appendicitis Diagnosis and Management
- Immune Cell Function and Interaction
- Vitamin D Research Studies
- Health Sciences Research and Education
- Salivary Gland Tumors Diagnosis and Treatment
- Colorectal Cancer Screening and Detection
- Immunotherapy and Immune Responses
University of Calgary
2014-2024
Cork University Hospital
2023
University College Cork
2023
SGS Germany GmbH (Germany)
2023
Exponent (United States)
2002
Macrophages are important innate immune cells that associated with two distinct phenotypes: a pro-inflammatory (or classically activated) subset prototypic macrophage functions such as inflammatory cytokine production and bactericidal activity, an anti-inflammatory alternatively activated (AAM)) linked wound healing tissue repair processes. In this study, we examined the effect of interlukein-6 on human murine polarization. The results indicate despite being commonly implicated in...
The adoptive transfer of alternatively activated macrophages (AAMs) has proven to attenuate inflammation in multiple mouse models colitis; however, the effect cryopreservation on AAMs, ability previously frozen AAMs block dinitrobenzene sulfonic acid (DNBS) (Th1) and oxazolone (Th2) colitis their migration postinjection remains unknown. Here we have found that while reduced mRNA expression canonical markers interleukin (IL)-4-treated [M(IL-4)], this step did not translate protein or...
Inflammatory bowel disease (IBD) increases risk of dysplasia and colorectal cancer. Advanced endoscopic techniques allow for the detection characterization IBD dysplastic lesions, but specialized training is not widely available. We aimed to develop validate an online platform improve colonic lesions in IBD: OPtical diagnosis Training Improve Characterization Bowel Disease (OPTIC-IBD).
Background: Neuroendocrine tumors (NET) are neoplasms that secrete peptides and neuroamines. For gastroenteropancreatic (GEP) NET, surgical resection represents the only curative option. Ten-year imaging surveillance programs recommended due to long time-to-recurrence following resection. We performed retrospective chart review evaluating radiation exposure practice patterns from of completely resected GEP NET. Methods: a cohort study cases with well-differentiated NET January 2005 July...
Abstract Background Neuroendocrine tumours (NET) are a heterogenous group of neoplasms that secrete peptides and neuroamines. For patients with potentially malignant gastroenteropancreatic (GEP) NET, surgical resection represents the only curative option. GEP NETs characterized by long periods disease-free survival time-to-recurrence following resection. Clinical guidelines recommend surveillance cross sectional imaging, either CT or MRI, for at least 10 years. Aims The purpose this study...