A5017230149- Inflammatory Bowel Disease
- SARS-CoV-2 and COVID-19 Research
- Microscopic Colitis
- Immunodeficiency and Autoimmune Disorders
- Pregnancy and Medication Impact
- Lysosomal Storage Disorders Research
- Vaccine Coverage and Hesitancy
- Cancer Immunotherapy and Biomarkers
- COVID-19 and healthcare impacts
- Colorectal Cancer Screening and Detection
- Carbohydrate Chemistry and Synthesis
- Gastrointestinal motility and disorders
- Potassium and Related Disorders
- Health, psychology, and well-being
- COVID-19 Clinical Research Studies
- Cutaneous Melanoma Detection and Management
- Endometriosis Research and Treatment
- Advanced Chemical Sensor Technologies
- Metastasis and carcinoma case studies
- Celiac Disease Research and Management
- Reproductive System and Pregnancy
- Fault Detection and Control Systems
- HIV/AIDS Research and Interventions
- Iron Metabolism and Disorders
- Chronic Myeloid Leukemia Treatments
Ospedale Sacro Cuore Don Calabria
2023-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2023-2025
Cork University Hospital
2023
University College Cork
2023
SGS Germany GmbH (Germany)
2023
Tio University
2023
University of Bari Aldo Moro
2020-2022
Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari
2021
University of Modena and Reggio Emilia
2008
University of Bologna
2008
Abstract Background Infliximab (IFX) biosimilars CT-P13 is available in a subcutaneous (SC) formulation. Both clinical trials and real life studies showed its effectiveness maintaining remission patients treated for several months of intravenous (IV) IFX. Although the current indications allow switch from IV to SC after two administrations, clinicians postpone achieving stable remission. What best time IFX unknown. This study aims evaluate endoscopic response, treatment persistence,...
Abstract Background Perianal fistulas may affect about 30% of patients with Crohn’s disease (CD). Management perianal (pCD) is difficult due to the presence complex and recurrent fistulae unlikely heal spontaneously or after medical-surgical treatment. . Previous studies have shown how use Video-Assisted Anal Fistula Treatment (VAAFT) can lead a benefit in terms symptom control pCD. The aim this study describe outcome VAAFT symptomatic improvement affected by Methods A retrospective was...
Abstract Background The best maintenance therapy after a steroid-responsive acute severe ulcerative colitis (ASUC) episode remains poorly studied and is not addressed in current guidelines. We aimed to compare the impact of different treatment strategies following hospitalization for ASUC. Methods Multicentric, multinational, retrospective cohort study including patients hospitalized with ASUC, between 2010-2021, who responded intravenous steroids (Oxford Criteria). Patients were categorized...
Kufs disease is the adult-onset form of neuronal ceroid lipofuscinosis (NCL). Its two clinical phenotypes are type A (progressive myoclonus epilepsy with dementia) and B (behavioral abnormalities dementia, associated pyramidal extrapyramidal signs).We describe evolution an atypical case characterized by progressive dementia focal occipital seizures.A healthy 37-year-old woman began showing memory deficits behavioral disturbances (apathy, lack inhibitions, untidiness). After 4 years, she...
The purpose of this study was to present data on the safety anti- severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination in a cohort inflammatory bowel disease (IBD) patients an ongoing multicenter (ESCAPE-IBD) sponsored by Italian Group for Inflammatory Bowel Disease (ClinicalTrials.gov Identifier: NCT04769258).Anti-SARS-CoV-2 administrated 809 IBD patients. Interviews were conducted report adverse events related vaccination. Of these 809, 346 surveyed pandemic burden and...
Inflammatory bowel disease (IBD) increases risk of dysplasia and colorectal cancer. Advanced endoscopic techniques allow for the detection characterization IBD dysplastic lesions, but specialized training is not widely available. We aimed to develop validate an online platform improve colonic lesions in IBD: OPtical diagnosis Training Improve Characterization Bowel Disease (OPTIC-IBD).
A 80-year-old woman underwent vulvar melanoma resection and segmental lung for pulmonary metastasis. Immunotherapy with Nivolumab was performed. One year later, the patient admitted gastrointestinal (GI) recurrent bleeding severe anemia. Esophagoastroduodenoscopy colonoscopy did not show any abnormality, while videocapsule endoscopy (VCE) revealed an irregular exophytic whitish area a "coal-black" central depression. Small bowel performed histological examination S100 protein strongly...
Background and objectives: Duodenal lymphocytosis (DL) is a condition characterized by enhanced infiltration of intraepithelial lymphocytes (IELs) in the duodenal mucosa, it can be linked to both gluten- non-gluten-related diseases, such as irritable bowel syndrome (IBS). Materials methods: We retrospectively selected patients with DL IBS. Formalin-embedded biopsy samples duodenum were collected. CD3 lymphocyte immunohistochemistry was used for IELs. The real-time polymerase chain reaction...
Journal Article Corrected proof Lack of Seroconversion Following COVID-19 Vaccination Is an Independent Risk Factor for SARS-CoV-2 Infection in Patients With Inflammatory Bowel Disease: Data from ESCAPE-IBD, IG-IBD Study Get access Fabio Salvatore Macaluso, MD, MD IBD Unit, "Villa Sofia-Cervello" Hospital, Palermo, Italy Address correspondence to: Macaluso; "'Villa Sofia-Cervello'" Viale Strasburgo 233, 90146 (fsmacaluso@gmail.com). https://orcid.org/0000-0001-5128-3846 Search other works by...
Abstract Background Vaccination is the most effective method to prevent and control SARS-CoV-2 infection. Recommendations consider patients with inflammatory bowel disease (IBD), Crohn’s (CD) ulcerative colitis (UC), a high-priority population COVID-19 vaccine administration. There were lot of concerns about vaccination safety in setting biological immunomodulatory drugs. The purpose this study was present data on anti-SARS-CoV-2 cohort IBD patients. These are preliminary an ongoing...
Abstract Background Covid-19 infection is an exceptional pandemic that has involved millions of people worldwide with dramatic humane, social and economic concerns. Since December 2020, two mRNA one inactivated vaccines were approved for administration. The vaccinal access calendar was scheduled according risk degree complications. In some regional setting patients inflammatory bowel diseases (IBD), Crohn’s disease (CD) ulcerative colitis (UC) considered fragile therefore had a priority...
Abstract Background During the SARS-CoV-2 pandemic there was a substantial change in providing medical care. National and international statements recommended avoiding face-to-face visit for treatment of patients especially chronic disease. Also lockdown social distancing cause lot concern among patients, which prefer avoid hospital facilities due to fear contracting COVID-19. For these reason reorganization inflammatory bowel disease follow-up shifting from traditional telemedicine whereas...
Abstract Background Patients with inflammatory bowel disease (IBD), ulcerative colitis (UC) and Crohn’s disease, claims to suffer a significant hindrance in everyday life, because of the frequency psychological complaints. The aim this study was identify analyze social functioning, work productivity assessment IBD patients correlate these parameters history activity disease. Methods An observational performed 99 patients. Psychosocial data were assessed through administration specific...