A5094277954- Inflammatory Bowel Disease
- Microscopic Colitis
- Helicobacter pylori-related gastroenterology studies
- Gastroesophageal reflux and treatments
- Autoimmune and Inflammatory Disorders
- Eicosanoids and Hypertension Pharmacology
- Gut microbiota and health
- Biosimilars and Bioanalytical Methods
- Diet and metabolism studies
- Autoimmune and Inflammatory Disorders Research
- Esophageal and GI Pathology
- Eosinophilic Esophagitis
- Potassium and Related Disorders
- Fatty Acid Research and Health
- Probiotics and Fermented Foods
- Metabolomics and Mass Spectrometry Studies
University of Padua
2024-2025
The gastrointestinal tract is home to trillions of diverse microorganisms collectively known as the gut microbiota, which play a pivotal role in breaking down undigested foods, such dietary fibers. Through fermentation these food components, short-chain fatty acids (SCFAs) acetate, propionate, and butyrate are produced, offering numerous health benefits host. production absorption SCFAs occur through various mechanisms within human intestine, contingent upon types fibers reaching specific...
The gastrointestinal tract is colonized by trillions of different microorganisms, named the gut microbiota, which key to degrade undigested food such as dietary fibers. fermentation these components leads production short-chain fatty acids (SCFA) acetate, propionate, and butyrate, exploit several beneficial roles for host’s health. Their absorption happen in ways human intestine depend on type fiber reaching microorganisms involved fermentation. supplementation SCFAs, mostly...
Abstract Background The best maintenance therapy after a steroid-responsive acute severe ulcerative colitis (ASUC) episode remains poorly studied and is not addressed in current guidelines. We aimed to compare the impact of different treatment strategies following hospitalization for ASUC. Methods Multicentric, multinational, retrospective cohort study including patients hospitalized with ASUC, between 2010-2021, who responded intravenous steroids (Oxford Criteria). Patients were categorized...
The esophagus, traditionally viewed as a sterile conduit, is now recognized dynamic habitat for diverse microbial communities. emerging evidence suggests that the esophageal microbiota plays an important role in maintaining health and contributing to disease. aim of this systematic review was synthesize current knowledge on composition, its variation between healthy individuals those with diseases, potential mechanisms through which these microorganisms influence pathology. A literature...
Introduction: Therapeutic drug monitoring (TDM) has proven to be a valuable strategy for optimizing biologic therapies, among which are anti-tumor necrosis factor (anti-TNF) treatments in inflammatory bowel disease (IBD). In particular, reactive TDM been shown manage treatment failures more cost-effectively than empirical dose adjustments anti-TNF drugs. However, several challenges currently impede the widespread adoption of clinical practice, particularly addressing delay between sample...
Background/Objectives: Restorative proctocolectomy with ileo-anal pouch anastomosis (IPAA) remains the preferred surgical treatment for ulcerative colitis (UC). However, complications like pouchitis can occur. This study aimed to describe patients who underwent IPAA inflammatory bowel disease (IBD) at Padua Hospital from 2005 2023 and identify risk factors pouchitis. Secondary objectives included evaluating effectiveness of biological therapy in chronic antibiotic-refractory (CARP), Crohn’s...