Cesare Ruffolo

ORCID: 0000-0001-7535-6595
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About
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Research Areas
  • Inflammatory Bowel Disease
  • Diverticular Disease and Complications
  • Colorectal Cancer Surgical Treatments
  • Microscopic Colitis
  • Anorectal Disease Treatments and Outcomes
  • Gastric Cancer Management and Outcomes
  • Cancer Immunotherapy and Biomarkers
  • Autoimmune and Inflammatory Disorders
  • Colorectal and Anal Carcinomas
  • Genetic factors in colorectal cancer
  • Gastrointestinal Tumor Research and Treatment
  • Colorectal Cancer Screening and Detection
  • Gastrointestinal disorders and treatments
  • Colorectal Cancer Treatments and Studies
  • Pelvic floor disorders treatments
  • Pancreatic and Hepatic Oncology Research
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Stoma care and complications
  • Neuroendocrine Tumor Research Advances
  • Immunotherapy and Immune Responses
  • Helicobacter pylori-related gastroenterology studies
  • Appendicitis Diagnosis and Management
  • Immune Cell Function and Interaction
  • Pancreatitis Pathology and Treatment

University of Padua
2009-2024

Azienda Ospedaliera di Padova
2004-2024

Ca' Foncello Hospital
2010-2019

AULSS 2 Marca Trevigiana
2010-2015

University Hospital of Ioannina
2007

Ospedale Maggiore
2007

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2007

University of Milan
2007

UCL Australia
2007

IFOM
2007

The gastrointestinal tract is home to trillions of diverse microorganisms collectively known as the gut microbiota, which play a pivotal role in breaking down undigested foods, such dietary fibers. Through fermentation these food components, short-chain fatty acids (SCFAs) acetate, propionate, and butyrate are produced, offering numerous health benefits host. production absorption SCFAs occur through various mechanisms within human intestine, contingent upon types fibers reaching specific...

10.3390/life14050559 article EN cc-by Life 2024-04-26

The gastrointestinal tract is colonized by trillions of different microorganisms, named the gut microbiota, which key to degrade undigested food such as dietary fibers. fermentation these components leads production short-chain fatty acids (SCFA) acetate, propionate, and butyrate, exploit several beneficial roles for host’s health. Their absorption happen in ways human intestine depend on type fiber reaching microorganisms involved fermentation. supplementation SCFAs, mostly...

10.20944/preprints202403.1638.v1 preprint EN 2024-03-27

Purpose: This study was designed to assess the role of fecal lactoferrin and calprotectin as markers intestinal inflammation in patients with Crohn's disease who have undergone ileocolonic resection. Methods: Sixty-three had resection for a median follow-up 40.5 (range, 5-102) months were enrolled. Clinical examination blood test performed, levels dosed. The predictors that resulted be significant at univariate analyses included two multiple regression analysis models. Results: mean level 21...

10.1007/s10350-007-0225-6 article EN Diseases of the Colon & Rectum 2007-04-30

This multicentric prospective study aimed to investigate how postoperative complications after surgery for colorectal cancer affect patients' quality of life and satisfaction with care.One hundred sixteen patients operated on were enrolled in this study. Patients answered three questionnaires about generic (EORTC QLQ-C30) disease-specific QLQ-CR29) treatment IN-PATSAT32) at the time admission 1 6 months surgery. Non-parametric tests linear multiple regression models used statistical...

10.1111/codi.12752 article EN Colorectal Disease 2014-08-23

Ovarian metastases from primary colorectal cancer occur in 3-8% of female patients. The aim this study was to assess the prognostic value radical oophorectomy for ovarian metastasis cancer.From our series 859 patients operated 1982 2005 ten with isolated were retrieved. diagnosis confirmed by pathology revision. Overall and disease-free survival after assessed compared literature data.The median follow-up resection 36 months (range 194-14). Survival analysis showed that rate metastasectomy...

10.1002/jso.20803 article EN Journal of Surgical Oncology 2007-04-18

Summary Background Ulcerative colitis (UC) and Crohn’s disease (CD) can cause metabolic inflammatory alterations. Aim To evaluate the relationships between parameters, plasma lipids phospholipid fatty acid (FA) composition in patients with active UC CD. Methods Diet, Harvey–Bradshaw Activity Index (HBAI), lipoproteins FA were assessed 60 CD 34 UC. Results No differences clinical parameters observed two groups. Total cholesterol correlated inversely number of bowel movements both groups...

10.1111/j.1365-2036.2008.03886.x article EN Alimentary Pharmacology & Therapeutics 2008-11-25

One of the most potent costimulatory molecules involved in recognition and killing tumor cells is CD80. However, its role molecular mechanisms regulating expression sporadic colorectal carcinogenesis remain elusive. Here, we provide evidence for CD80 overexpression human colon epithelial derived from preneoplastic mucosa. Expression on colonic isolated normal mucosa, neoplastic specimens was assessed by flow cytometry. WT CD80KO mice received azoxymethane to induce lesions sacrificed perform...

10.1186/s13046-019-1205-0 article EN cc-by Journal of Experimental & Clinical Cancer Research 2019-05-09

Long-term daily use of aspirin reduces incidence and mortality due to colorectal cancer (CRC). This study aimed analyze the effect on tumor microenvironment, systemic immunity, healthy mucosa surrounding cancer.

10.1002/cncr.35297 article EN Cancer 2024-04-22

Abstract Background This study examined the outcome of surgery for symptomatic Crohn's rectovaginal fistula (RVF) and assessed effect therapy with antibody against tumour necrosis factor (TNF) on healing. Methods Fifty-six patients disease underwent a RVF between January 1993 December 2006. Outcome analysis was performed in February 2008 relation to surgical procedures used anti-TNF treatment. Results Four healed still had stoma at final follow-up other reasons were excluded from analysis....

10.1002/bjs.6661 article EN British journal of surgery 2009-08-17

// Marco Scarpa 1,* , Cesare Ruffolo 2,* Fabio Canal 3 Melania 1 Silvia Basato 4 Francesca Erroi Alain Fiorot 2 Lucia Dall'Agnese Anna Pozza Andrea Porzionato 5 Ignazio Castagliuolo Angelo P. Dei Tos Nicolò Bassi and Carlo Castoro Surgical Oncology Unit, Veneto Institute of IOV-IRCCS, Padova, Italy General Surgery Unit (IV), "Ca' Foncello" Hospital, Treviso, Pathology Department Surgical, Oncological Gastroenterological Sciences, University Molecular Medicine, * These authors have...

10.18632/oncotarget.6179 article EN Oncotarget 2015-10-19
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