- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Systemic Lupus Erythematosus Research
- Advanced MRI Techniques and Applications
- Multiple Sclerosis Research Studies
- Peripheral Neuropathies and Disorders
- Biomedical Text Mining and Ontologies
- EEG and Brain-Computer Interfaces
- Neural dynamics and brain function
- Health Systems, Economic Evaluations, Quality of Life
- Color Science and Applications
- Brain Metastases and Treatment
- Neurological Complications and Syndromes
- Autoimmune Neurological Disorders and Treatments
- Myasthenia Gravis and Thymoma
- Transcranial Magnetic Stimulation Studies
- Medical and Biological Ozone Research
- Effects of Environmental Stressors on Livestock
- Heat Transfer Mechanisms
- Autoimmune Bullous Skin Diseases
- Autoimmune and Inflammatory Disorders
- Galectins and Cancer Biology
- Bioinformatics and Genomic Networks
- Spatial Neglect and Hemispheric Dysfunction
- Thyroid and Parathyroid Surgery
Institut de l’Elevage
2023
Assistance Publique – Hôpitaux de Paris
2021
Inserm
1988-2021
Université Sorbonne Nouvelle
2021
Pitié-Salpêtrière Hospital
2021
Sorbonne Université
2018-2021
Institut du Cerveau
2017-2021
Centre National de la Recherche Scientifique
2017-2021
Laboratoire Plasticité du Cerveau
2021
Institut Curie
2021
The administration of the immunosuppressive humanized monoclonal antibody CAMPATH 1-H, which recognizes CD52 on lymphocytes and monocytes, is associated with a first-dose cytokine-release syndrome involving TNFalpha, IFNgamma, IL-6 clinically. In vitro models have been used to establish cellular source mechanism responsible for cytokine release, demonstrating that release isotype dependent, rat IgG2b human IgG1 inducing highest levels was inhibited CD16, low affinity Fc-receptor IgG...
We present Clinica ( www.clinica.run ), an open-source software platform designed to make clinical neuroscience studies easier and more reproducible. aims for researchers (i) spend less time on data management processing, (ii) perform reproducible evaluations of their methods, (iii) easily share results within institution with external collaborators. The core is a set automatic pipelines processing analysis multimodal neuroimaging (currently, T1-weighted MRI, diffusion PET data), as well...
The changing incidence of ischemic stroke is major concern in view its public health impact, to define the population concerned, identify risk factors, and set up health-care systems. aim this study was evaluate time trends associated with all subtypes transient attacks a well-defined for 10 years.Since 1985, registry has recorded each patient living Dijon (France) who suffered from cerebrovascular disease (CVD) regardless type management. This involved patients suffering their first (TIAs)...
The immune and hormonal systems are closely linked. In several animal models of diseases as well in multiple sclerosis (MS), sex hormones have been shown to modulate clinical course.1,2 Some women followed for MS may infertility resulting treatment vitro fertilization (IVF). this regard, the type drugs used, which modify status, might affect disease activity patients with MS. By matching IVF databases from University Hospital Nantes, France, we found four who had undergone six cycles over...
Abstract White matter bundles linking gray nodes are key anatomical players to fully characterize associations between brain systems and cognitive functions. Here we used a multivariate lesion inference approach grounded in coalitional game theory (multiperturbation Shapley value analysis, MSA) infer causal contributions of white visuospatial orienting attention. Our work is based on the characterization patterns 25 right hemisphere stroke patients analysis their impact three...
Incidence of multiple sclerosis (MS) was prospectively determined within the population city Dijon (94,000 inhabitants under 60 years old) at 47 degrees northern latitude, in Burgundy, France. All incident cases were diagnosed according to criteria Poser, associated study cerebrospinal fluid, evoked potentials and cerebral magnetic resonance imaging. Diagnosis assessed all by a neurologist working either University Hospital (four neurologists) or private offices (seven neurologists). The...
Résumé La validité du diagnostic psychiatrique a, depuis toujours, soulevé des objections et critiques. Malgré tous les progrès récents dans ce domaine, on est encore loin d’une nosologie acceptée par pays. Dans le domaine psychoses non affectives, nosologies française américaine sont différentes. un premier temps auteurs décrivent épisodes classées «bouffée délirante aiguë», entité clinique traditionnellement française, au moyen DSM III. Le reclassement, selon critères III, de 55 patients...
Different non-invasive neuroimaging modalities and multi-level analysis of human connectomics datasets yield a great amount heterogeneous data which are hard to integrate into an unified representation. Biomedical ontologies can provide suitable integrative framework for domain knowledge as well tool facilitate information retrieval, sharing comparisons across scales, species. Especially, it is urgently needed fill the gap between neurobiology in vivo order better take account reality...
ABSTRACT Theoretical and experimental evidence suggest that the induction of oscillatory activity by an external rhythmic source on a specific brain area is maximally efficient if input pattern matches its so-called ‘natural’ frequency, defined as predominant neural rhythm at which this tends to fluctuate spontaneously. Based principle, single pulse Transcranial Magnetic Stimulation (TMS) coupled scalp electroencephalography (EEG) has provided frequency-specific power increases within unique...