Yun-Xia Chen

ORCID: 0000-0002-6993-320X
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About
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Research Areas
  • Sepsis Diagnosis and Treatment
  • Pneumonia and Respiratory Infections
  • Emergency and Acute Care Studies
  • Hemodynamic Monitoring and Therapy
  • Trauma and Emergency Care Studies
  • Respiratory viral infections research
  • Thyroid Disorders and Treatments
  • Cytomegalovirus and herpesvirus research
  • Clinical Reasoning and Diagnostic Skills
  • Pediatric health and respiratory diseases
  • Heart Failure Treatment and Management
  • Neuropeptides and Animal Physiology
  • Endometrial and Cervical Cancer Treatments
  • Lung Cancer Diagnosis and Treatment
  • Abdominal Trauma and Injuries
  • Lung Cancer Treatments and Mutations
  • Nosocomial Infections in ICU
  • MicroRNA in disease regulation
  • Autophagy in Disease and Therapy
  • Mesenchymal stem cell research
  • Neonatal Respiratory Health Research
  • Urinary Tract Infections Management
  • Salivary Gland Disorders and Functions
  • Complement system in diseases
  • Clinical Nutrition and Gastroenterology

Army Medical University
2025

Henan Provincial People's Hospital
2006-2024

Zhengzhou University
2024

Shenzhen University
2024

South China Agricultural University
2024

Guangdong Academy of Agricultural Sciences
2024

Chongqing Medical University
2011-2024

Children's Hospital of Chongqing Medical University
2023-2024

Nanjing University
2016-2024

Guangzhou Medical University
2013-2024

Presepsin levels are known to be increased in sepsis. The aim of this study was evaluate the early diagnostic and prognostic value compared with procalcitonin (PCT), Mortality Emergency Department Sepsis (MEDS) score Acute Physiology Chronic Health Evaluation II (APACHE II) septic patients an emergency department (ED) investigate as a new biomarker sepsis.This enrolled 859 consecutive at least two criteria for systemic inflammatory response syndrome (SIRS) who were admitted Beijing Chao-yang...

10.1186/cc13070 article EN cc-by Critical Care 2013-10-20

The quick Sepsis-related Organ Failure Assessment (qSOFA) is a new screening system for sepsis that has prognostic performance equal to the full SOFA patients with suspected infection outside intensive care unit (ICU). predictive value of qSOFA mortality and site in pneumonia not clear. present study was designed investigate qSOFA, CRB-65 (confusion, respiratory rate ≥30/minute, systolic blood pressure <90 mmHg or diastolic ≤60 mmHg, age ≥65 years) CRB mmHg) mortality, hospitalisation ICU...

10.1186/s13054-016-1351-0 article EN cc-by Critical Care 2016-06-01

We hypothesised that endothelin (ET)-1 plays an important role in the pathogenesis of emphysema. attempted to apply ET-1 receptor antagonists demonstrate and further elucidate molecular pathways through which may cause emphysematous changes. Sprague-Dawley rats were divided into four groups: control, cigarette smoke extract (CSE), CSE+BQ-123 (a selective type A (ET ) antagonist) CSE+bosentan mixed ET /ET B antagonist). The CSE was injected intraperitoneally once a week for 3 weeks, BQ-123 or...

10.1183/09031936.00003909 article EN European Respiratory Journal 2009-11-06

To investigate the predictive performance of lactate, CURB-65, and a combination lactate CURB-65 (LAC-CURB-65) for mortality, hospitalisation intensive care unit (ICU) admission in pneumonia patients emergency department (ED).Consecutive adult with presenting from January 2012 to May 2014 were divided into low-, moderate- high-risk groups according (<2.0, 2.0-4.0, >4.0 mmol/L), (≤1, 2, ≥3) LAC-CURB-65 (patients two low risks, any moderate risk, high risk) values. Mortality, ICU rates...

10.1136/thoraxjnl-2014-206461 article EN Thorax 2015-02-23

Abstract Introduction The predisposition, infection, response and organ dysfunction (PIRO) staging system was designed as a stratification tool to deal with the inherent heterogeneity of septic patients. present study conducted assess performance PIRO in predicting multiple (MOD), intensive care unit (ICU) admission, 28-day mortality patients emergency department (ED), compare this scoring Mortality Emergency Department Sepsis (MEDS) Acute Physiology Chronic Health Evaluation (APACHE II)...

10.1186/cc13832 article EN cc-by Critical Care 2014-04-16

10.1016/j.ajem.2013.03.017 article EN The American Journal of Emergency Medicine 2013-05-17

<i >Objective</i>. The aim of the study was to assess adrenomedullin (AM) as a predictor for development severe sepsis and septic shock in emergency department (ED). >Method</i>. From December 2011 October 2012, 372 consecutive patients admitted ED were enrolled. AM examined every patient. All followed up 3 days. outcome variable or shock. predictive ability evaluated by binary logistic regression analysis receiver operating characteristic (ROC) curve. >Result</i>. On admission, differences...

10.1155/2013/960101 article EN cc-by BioMed Research International 2013-01-01

Hepatopulmonary syndrome (HPS) is a lung complication in various liver diseases, with high incidence, poor prognosis and no effective non-surgical treatments patients hepatocirrhosis. Therefore, assessing HPS pathogenesis to explore proper therapy strategies clinically relevant. In the present study, male Sprague-Dawley rats underwent sham operation or common bile duct ligation (CBDL). Two weeks post-surgery, following groups were set up for 2 of treatment: + normal saline, CBDL CXCR2...

10.1042/cs20160593 article EN Clinical Science 2016-11-23

Abstract Kidney transplantation (KT) is the best therapy available for patients with end-stage renal disease, but postoperative infections are a significant cause of mortality. In this retrospective study frequency, risk factors, causative pathogens, and clinical manifestations infection in KT recipients from Beijing Chao-Yang Hospital, Capital Medical University were investigated. Ninety-seven who hospitalized between January 2010 December 2016 included. Clinical characteristics, surgery...

10.1097/md.0000000000017312 article EN cc-by-nc Medicine 2019-09-01

The prevalence and molecular characteristics of Bartonella infections in small rodents the Zhongtiao Mountain, China have been explored. In this study, liver, spleen kidney tissues captured were used for spp . detection identification by combination real-time PCR transfer-mRNA ( ssrA ) gene traditional sequencing citrate synthase gltA gene. It was shown that 49.52% (52/105) positive .. infection rate different gender χ 2 = 0.079, P 0.778) 0.233, 0.890) did not statistical difference, but...

10.1371/journal.pone.0264591 article EN cc-by PLoS ONE 2022-02-28

Objective To evaluate the effectiveness and safety of Xuebijing (XBJ) injection in therapy sepsis.Methods It is a prospective,randomized controlled trial conducted multicenter.Totally 731 patients with sepsis were enrolled from January to December 2011 at 37 centers randomly (random number) separated into XBJ group (n =392) control =339).Basic was adoptd both groups,but additionally used group.The evaluated by comparing differences MEDS score,APACHE Ⅱ score,DIC score,SOFA score,coagulation...

10.3760/cma.j.issn.1671-0282.2013.02.006 article EN Zhonghua jizhen yixue zazhi 2013-02-10
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