A5063091333- Pulmonary Hypertension Research and Treatments
- Vascular Anomalies and Treatments
- COVID-19 Clinical Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Liver Disease and Transplantation
- Transplantation: Methods and Outcomes
- SARS-CoV-2 and COVID-19 Research
- Heart Failure Treatment and Management
- Tracheal and airway disorders
- COVID-19 diagnosis using AI
- Cystic Fibrosis Research Advances
- Management of metastatic bone disease
- Respiratory viral infections research
- Hematopoietic Stem Cell Transplantation
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular Issues in Pregnancy
- Atrial Fibrillation Management and Outcomes
- Pleural and Pulmonary Diseases
- Medical Imaging and Pathology Studies
- Cardiac Arrhythmias and Treatments
- Systemic Sclerosis and Related Diseases
- Vascular Malformations and Hemangiomas
- IgG4-Related and Inflammatory Diseases
- Inhalation and Respiratory Drug Delivery
- Infections and bacterial resistance
Monash University
2023
Monash Health
2023
King Faisal Specialist Hospital & Research Centre
2009-2022
University of Pittsburgh Medical Center
2021
Riyadh Armed Forces Hospital
2008
Pulmonary Associates
2005
King Khalid University Hospital
1998
King Saud University
1998
Bronchiolitis obliterans (BO) is a serious noninfectious pulmonary complication following allogeneic bone marrow transplantation (BMT). Azithromycin, macrolide antibiotic, may have beneficial effect in BO through its anti-inflammatory effect. The aim of the current study was to investigate potential azithromycin on function tests (PFTs) complicating BMT. PFTs 153 post-BMT patients were followed; eight out (12%) developed obstructive airway disease their PFTs, along with characteristic...
Adherence to COPD treatment in Turkey and Saudi Arabia: results of the ADCARE study Nurdan Kokturk,1 Mehmet Polatli,2 I Kivilcim Oguzulgen,1 Sarfraz Saleemi,3 Mohammed Al Ghobain,4 Javed Khan,5 Adam Doble,6 Luqman Tariq,7 Fayaz Aziz,7 Abdelkader El Hasnaoui7 1Department Pulmonary Medicine, School Gazi University, Besevler, Turkey; 2Department Adnan Menderes Aydin, 3Section Department King Faisal Specialist Hospital Research Center, Riyadh, Arabia; 4Department College Saud bin Abdulaziz...
Middle Eastern respiratory syndrome caused by novel coronavirus (MERS CoV) has been a major public health challenge since it was first described in 2012 Saudi Arabia. So far, there is no effective treatment for this serious illness, which features high mortality rate. We report an initial experience of the use ribavirin and interferon (IFN)-a2b management MERS CoV at tertiary care hospital.A case series 6 patients admitted with confirmed diagnosis were treated IFN-a2b addition to supportive...
Portopulmoanry hypertension (POPH) is a form of pulmonary arterial (PAH) associated with portal or without underlying chronic liver disease. POPH increasingly recognized and recent evidence suggests that it one the leading causes PAH. The pathophysiology poorly understood although pathological changes in vasculature advanced are similar to those seen idiopathic hypertension. prognosis patients disease who also suffer from significant considered be poor. Higher degree artery pressure (PAP)...
Hypertension (previously called Saudi Advisory Group for Pulmonary Hypertension) has published the first guidelines on diagnosis and treatment of pulmonary arterial hypertension (PAH) back in 2008. [1]That guideline was very detailed extensive reviewed most aspects (PH).
Hereditary hemoglobin disorders affecting the globin chain synthesis namely thalassemia syndromes and sickle cell disease (SCD) are most common genetic in human. Around 7% of world population carries genes for these disorders, mainly Mediterranean Basin, Middle Far East, Sub-Saharan Africa. An estimated 30 million people worldwide living with disease, while 60-80 carry beta trait. About 400,000 children born severe hemoglobinopathies each year.<br>Cardiovascular complications include left...
Mycobacterium tuberculosis infection (TB) masquerading as lung tumor is well reported, but its mimicry metastatic thoracic cancer rare. We report the case of a young male who presented with clinical and radiological picture investigations confirmed it TB. A 35-year-old male, 18-pack year smoking history, dry cough, anorexia, weight loss, lower back left hip pain. Chest imaging showed right upper lobe speculated mass mediastinal hilar lymphadenopathy lytic lesion in sacral area. Magnetic...
Background Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, progressive vascular disease with poor prognosis if left untreated. This study aims to assess the patient characteristics, treatment approach and clinical survival outcomes for CTEPH patients enrolled in Systematic Prospective Follow Up Better Understanding of Clinical Characteristics Patients Pulmonary Hypertension Disease (SAUDIPH) registry. Methods presents subanalysis SAUDIPH registry hypertension, established...
This is a retrospective review of consecutive patients admitted with diagnosis COVID-19 confirmed by Real Time Reverse Transcription Polymerase Chain Reaction (RT-PCR). Clinical, laboratory, radiology and treatment outcome data were obtained reviewing electronic medical record.
ABSTRACT Background and objective This study presents the first results of ‘SAUDIPH’ registry, aiming to assess patient characteristics, treatment approach clinical survival outcomes in patients with PAH. Methods The registry enrolled Group 1 4 PH under management a specialized tertiary care centre from 2004 2018. Changes baseline last follow‐up visit were assessed. Results A total 222 enrolled, was most frequent aetiology (57.7%). Mean age at diagnosis 32 years. mPAP 55.0 mm Hg higher for...
Bronchiolitis obliterans syndrome is a significant postallogeneic hematopoietic stem cell transplant problem. Recent data in lung patients suggest an association with gastroesophageal reflux disease and bronchiolitis syndrome. We studied posthematopoietic for its response to proton pump inhibitor.Seven were studied. Gastroesophageal was assessed by 24-hour pH monitoring Bravo catheter-free radio capsule. Patients positive started on omeprazole. Pretreatment posttreatment pulmonary function...
Even though pulmonary arterial hypertension (PAH) remains an incurable disease, the combination of PAH-specific therapies allowed evolving from symptom-based strategies to others aiming move patients low-risk conditions. Endothelin-1 (ET-1) receptor antagonists emerged as specific-PAH drugs that can be used in with other specific therapies. This work aimed perform a prospective clinical assessment PAH switched bosentan macitentan (POTENT), due inadequate response. POTENT is prospective,...
Extensive research has been devoted to cystic fibrosis-related brochiectasis, compared with non-cystic fibrosis bronchiectasis but the latter is more common and results in significant morbidity mortality. We assessed relationship between pulmonary function test (PFT) findings sputum bacteriology, blood gases, number of hospital admissions mortality patients bonchiectasis (NCFB).We conducted a retrospective review 88 consecutive admitted exacerbation over 5 years from 1996 2001. Demographic...
Portopulmonary hypertension (POPH) is defined as pulmonary arterial (PAH) complicated by portal hypertension, with or without advanced hepatic disease. Significant percentage of patients cirrhotic liver disease has high cardiac output and subsequently elevated pressures (PAP). However, POPH develop a progressive increase in vascular resistance (PVR), which generally lower than that observed other forms PAH. <br>The prognosis untreated very poor the outcome transplant (LT) those determined...
Pulmonary arterial hypertension (PAH) is a major cause of morbidity and mortality in patients with systemic sclerosis (SSc). The objective this study to describe the clinical characteristics, mortality, predictors SSc-PAH Saudi patients.Retrospective chart review SSc who were followed for at least 1 year three tertiary care centers Arabia was conducted. Clinical information, echocardiographic findings, right heart catheterization (RHC) results collected. Descriptive statistics used...
ABSTRACT Background The role of hydroxychloroquine (HCQ) and azithromycin in the treatment COVID-19 its effect on SARS-CoV-2 viral clearance is not known. Methods This a retrospective observational study to assess HCQ Azithromycin duration from symptom onset negative PCR using nasopharyngeal swab hospitalized patient with COVID-19. Eighty-five patients were included study, 65 (Hydroxychloroquine + Azithromycin) 20 non-HCQ group. Measurement gender, age disease severity time was measured....
We report a rare case of IgG4-associated mediastinal fibrosis with complete superior vena cava (SVC) obstruction successfully managed by thrombolysis and stenting in 33-year-old male. The patient presented mass lesion clinical findings SVC obstruction. Surgical biopsy the histology immunohistochemistry staining established diagnosis IgG4 associated fibrosis. was treated systemic steroid rituximab, but despite treatment, thromboses persisted, surgical intervention declined thoracic surgeon...
<i>Background:</i> COVID-19 caused by SARS CoV-2 involves respiratory system leading to failure and Acute Respiratory Distress Syndrome (ARDS) in critical patients. Several chest imaging features have been reported patients with ranging from focal diffuse lung opacities. There is no data Saudi Arabia on the findings these <i>Material Methods:</i> CT of 29 who were admitted confirmed diagnosis real-time reverse transcriptase polymerase chain reaction (RT-PCR) was reviewed. Radiology...