A5011212448- Glioma Diagnosis and Treatment
- Brain Metastases and Treatment
- IgG4-Related and Inflammatory Diseases
- CNS Lymphoma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Traumatic Brain Injury and Neurovascular Disturbances
- Meningioma and schwannoma management
- Neurofibromatosis and Schwannoma Cases
- Mosquito-borne diseases and control
- Vasculitis and related conditions
- Spine and Intervertebral Disc Pathology
- Histone Deacetylase Inhibitors Research
- Vascular Malformations Diagnosis and Treatment
- Spinal Dysraphism and Malformations
- Ocular Oncology and Treatments
- Traumatic Brain Injury Research
- Head and Neck Surgical Oncology
- Ocular Diseases and Behçet’s Syndrome
- Autoimmune Neurological Disorders and Treatments
- Spinal Hematomas and Complications
- Migraine and Headache Studies
- Microtubule and mitosis dynamics
- Vibrio bacteria research studies
- Pericarditis and Cardiac Tamponade
- Management of metastatic bone disease
Mayo Clinic in Arizona
2018-2025
Mayo Clinic
2018-2024
Mayo Clinic in Florida
2014-2024
Neurological Surgery
2024
WinnMed
2018-2024
Neurology, Inc
2019-2024
Hawke's Bay Hospital
2018
Pulmonary hypertension (PH) has been found to have significant morbidity and mortality. The treatment of PH advanced considerably with increasingly more effective safer options. With an increasing effort diagnose patients early, non-invasive techniques are often used screen those likely PH. Computerized tomography (CT) chest scans utilized in the evaluation exertional dyspnea, including suspected main role CT scan is evaluate for any associated underlying diseases. There attempts address...
Medulloblastomas are embryonal tumors predominantly affecting children. Recognition of molecularly defined subgroups has advanced management. Factors influencing the management and prognosis adult patients with medulloblastoma remains poorly understood.
To assess the long-term outcomes of patients hospitalized with severe West Nile neuroinvasive disease.Retrospective cohort.Patients admitted to a referral center (Saint Mary's Hospital, Mayo Clinic).Twenty-six disease were identified by retrospective search electronic database Saint Hospital from January 1999 November 2016.Retrospective medical records review and prospective telephone follow-up.Functional disability cognitive evaluated modified Rankin Scale Telephone Interview for Cognitive...
Introduction: Glioblastoma is a uniformly lethal primary central nervous system neoplasm. Despite the increased understanding of its pathophysiology and treatment advancements, median overall survival for patients with glioblastoma, IDH-wild type remains 14 to 21 months from diagnosis. Case Report: We present case 48-year-old female who presented focal seizure was found have right frontal lobe mass on brain magnetic resonance imaging. She underwent gross total resection received histological...
A woman in her 30s presented with acute-onset encephalopathy immediately following bilateral CT digital subtraction myelogram performed to identify a suspected cerebrospinal fluid leak. On examination, the patient's level of consciousness fluctuated between lethargy and stupor. When eyes were
Background: Survival of patients with glioblastoma (GBM) increased in the 2000s, most prominently after addition temozolomide to standard-of-care treatment protocol. The reason for subsequent improvements survival late 2000s and early 2010s was less clear, explanations including introduction bevacizumab, better surgical methods, advances supportive care. It is uncertain whether trend improving population-level has continued. Materials Methods: Data from Surveillance, Epidemiology, End...
Pilocytic astrocytomas (PA) are highly vascular tumors with endothelial growth factor (VEGF)-vascular receptor-2 (VEGFR-2) signaling present in the tumor vasculature. PA may, therefore, be responsive to VEGF blockade bevacizumab (BEV). Data regarding use of BEV refractory adults limited primarily case reports and series patients recurrent PA. We conducted a single-center, retrospective cohort study from 2009 2018. screened 426 pathologically confirmed identified 5 adult who received at our...
To determine whether there is a drug-drug interaction precluding the concomitant use of levetiracetam and high-dose methotrexate (HDMTX).Retrospective analysis.Large academic tertiary care medical center.Adult lymphoma patients who received HDMTX as 4-h infusion with or without levetiracetam.Generalized estimating equations clustered on patient were used to assess each outcome. The primary outcome was incidence delayed MTX elimination (MTX level >1 µmol/L at 48 h). Secondary outcomes...
Isolated spinal pachymeningitis is rarely encountered in clinical practice. Narrowing down the specific cause individual patients challenging as possible etiologies are broad, there substantial overlap presentation, and obtaining adequate data complex, often affected by prior empiric treatments, including steroids. Here, we describe a rare patient with resulting subacute to chronic progressive lower extremity weakness eventually paraplegia. We discuss how obtained final diagnosis, provide...
We report a case highlighting key clinical, CSF, and imaging findings of primary diffuse leptomeningeal gliomatosis the spine.
A 66-year-old man presented with a 1-year history of progressive cognitive decline, gait instability, and hearing loss.MRI the brain showed extensive pachymeningeal thickening enhancement marked occlusion intracranial dural venous sinuses (Figure 1).Lumbar puncture revealed pleocytosis at 140 cells/mm 3 (96% lymphocytes) elevated protein 560 mg/dL.Serum syphilis screen, immunoglobulin G4, proteinase antibody were negative.Myeloperoxidase was borderline positive.Systemic evaluation evidence...