A5088653481- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Bacterial biofilms and quorum sensing
- Bacterial Identification and Susceptibility Testing
- Antibiotic Use and Resistance
- COVID-19 and Mental Health
- Pharmaceutical and Antibiotic Environmental Impacts
- Vibrio bacteria research studies
- Mental Health Treatment and Access
- Viral gastroenteritis research and epidemiology
- Burn Injury Management and Outcomes
- Cancer Risks and Factors
- Resilience and Mental Health
- Child Nutrition and Water Access
- Healthcare professionals’ stress and burnout
- Nutritional Studies and Diet
- Biochemical and Structural Characterization
- Liver Disease Diagnosis and Treatment
- Infections and bacterial resistance
- Escherichia coli research studies
- Antimicrobial agents and applications
- Wound Healing and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Parasitic Infections and Diagnostics
- Medical Device Sterilization and Disinfection
Al-Azhar University – Gaza
2015-2025
Al-Azhar University
2022
Rutgers, The State University of New Jersey
2015
International Center for Public Health
2013
University of Münster
2006-2009
University at Buffalo, State University of New York
2009
University Hospital Münster
2006
Nasal carriage of Staphylococcus aureus among hospital personnel is a common cause acquired infections. Emergence drug resistant strains especially methicillin S. (MRSA) serious problem in environment. Therefore, the aim this study was to determine nasal rate and MRSA Health Care Workers (HCWs) at Al Shifa Hospital, major Gaza Strip.A cross sectional conducted on 200 HCWs. swabs were collected during February - April 2015, cultured blood mannitol salt agar. The isolates identified as based...
Abstract Background The current pandemic of COVID-19 impacted the psychological wellbeing populations globally. Objectives We aimed to examine extent and identify factors associated with distress, fear coping. Methods conducted a cross-sectional study across 17 countries during Jun-2020 Jan-2021. Levels distress (Kessler Psychological Distress Scale), (Fear coping (Brief Resilient Coping Scale) were assessed. Results A total 8,559 people participated; mean age (±SD) was 33(±13) years, 64%...
Klebsiella pneumoniae carbapenemase (KPC)-producing K. strains have spread worldwide and become a significant public health threat. blaKPC, the plasmid-borne KPC gene, was frequently identified on numerous transferable plasmids in different incompatibility replicon groups. Here we report complete nucleotide sequence of novel blaKPC-3-harboring IncI2 plasmid, pBK15692, isolated from multidrug-resistant ST258 strain New Jersey hospital 2005. pBK15692 is 78 kb length carries backbone that...
Extended-spectrum β lactamases (ESBLs), have the ability to hydrolyze and cause resistance various types of β-lactam antibiotics, including extended-spectrum (or third-generation) cephalosporins (e.g., cefotaxime, ceftriaxone, ceftazidime) monobactams aztreonam). ESBL-producing Gram negative bacteria is still posing significant therapeutic challenges.To assess prevalence molecular characteristics ESBL producing bacilli, isolated from a cohort pediatric patients in Gaza hospitals.A total 322...
Background Methicillin-resistant Staphylococcus aureus (MRSA) is an important pathogen in both community and healthcare-related settings worldwide. Current knowledge regarding the epidemiology of S. MRSA Gaza based on a single community-based carriage study. Here we describe cross-sectional analysis 215 clinical isolates collected from Al-Shifa Hospital during 2008 2012. Methods All were characterized by spa typing, SCCmec detection genes encoding Panton-Valentine leukocidin (PVL) toxic...
Carbapenem-resistant Klebsiella pneumoniae (CRKP) is a difficult to treat organism owing limited therapeutic options. So far, little known about the molecular characteristics of CRKP in Palestine. The aim this study was investigate antimicrobial resistance patterns, multilocus sequence types (ST) and genes among clinical K. isolates from hospitalized patients Gaza Strip, blood cultures (n = 55) were collected at two hospitals Strip (2023) identified by MALDI-TOF-MS. Antimicrobial...
In this study, full-genome DNA microarrays based on the sequence of Staphylococcus aureus N315 were used to compare transcriptome a clinical S. strain with normal phenotype that its isogenic mutant stable small-colony-variant (SCV) (hemB::ermB). addition standard statistical analyses, systems biology advances applied identify reporter metabolites and achieve more detailed survey genome-wide expression differences between hemB parental strain. Genes enzymes involved in glycolytic fermentative...
Infections due to small-colony variants (SCVs) of Staphylococcus aureus in patients with chronic and recurrent infections are an emerging problem; however, studies this subpopulation hampered by the fact that SCVs may exhibit unstable phenotypes, making them difficult study, particularly broth media. In two S. sets comprising (i) normal (ii) SCV phenotype (clonal phenotype) recovered from clinical specimens, as well (iii) corresponding site-directed mutants displaying (knockout hemB) (iv)...
ABSTRACT We report the first multidrug-resistant Proteus mirabilis strain producing carbapenemase OXA-48 (Pm-OXA-48) isolated at Al-Shifa hospital in Gaza, Palestine. Draft genome sequencing of Pm-OXA-48 identified 16 antimicrobial resistance genes, encoding to β-lactams, aminoglycosides, fluoroquinolones, phenicols, streptothricin, tetracycline, and trimethoprim-sulfamethoxazole. Complete bla -harboring plasmid revealed that it is a 72 kb long IncL/M plasmid, harboring gene , extended...
Liquefied petroleum gas (LPG) is widely used in the Gaza Strip for domestic purposes, agriculture and industry and, illegally, cars.This study aimed to identify possible health effects on workers exposed LPG governorates.Data were collected by a questionnaire interview, haematological biochemical analyses of venous blood samples made from 30 at filling distribution stations apparently healthy controls.Statistically significant differences found all self-reported healthrelated complaints...
Abstract Background The ongoing global crisis of Higher Education (HE) institutions during the post-COVID-19 pandemic period has increased likelihood enduring psychological stressors for staff. This study aimed to identify factors associated with job insecurity, burnout, distress and coping amongst staff working at HE globally. Methods An anonymous cross-sectional was conducted in 2023 across 16 countries. Job insecurity measured using Insecurity Scale (JIS), burnout Perceived Burnout...
ABSTRACT While coagulase-negative staphylococci (CoNS), with their ability to form a thick, multilayered biofilm on foreign bodies, have been identified as the major cause of implant-associated infections, no data are available about formation by staphylococcal small-colony variants (SCVs). In past years, number device-associated infections due SCVs were described, among them, several pacemaker CoNS auxotrophic hemin. To test characteristics CoNS, in particular, study we generated stable...
Extended-spectrum β-lactamase-producing organisms causing urinary tract infections are increasing in incidence and pose a major impendence to health-care facility, having limited therapeutic options. This study aimed assess the prevalence of ESBLs Enterobacteriaceae isolates Gaza strip, Palestine, characterize β-lactamase types associated resistance genes.Eighty-five were recovered from within three months Strip hospitals. The characterization genes genetic environments CTX-M, identification...
Gastroenteritis is considered as one of the leading causes illness and death in children under 5 years age, especially developing countries. It major public health problems among childhood Gaza strip, Palestine. This study was conducted to determine prevalence enteric pathogen-associated community gastroenteritis kindergarten Gaza. A total 150 stool samples were collected investigated for parasitic, viral bacterial pathogens at Al Azhar microbiology laboratories by using standard...
Healthcare workers (HCWs) have been impacted psychologically due to their professional responsibilities over the prolonged era of coronavirus disease 2019 (COVID-19) pandemic. The study aimed identify predictors psychological distress, fear, and coping during COVID-19 pandemic among HCWs.A cross-sectional online survey was conducted self-identified HCWs across 14 countries (12 from Asia two Africa). Kessler Psychological Distress Scale, Fear Brief Resilient Coping Scale were used assess...
ABSTRACT Carbapenemase-producing Gram-negative bacteria (CP-GNB) have increasingly spread worldwide, and different families of carbapenemases been identified in various bacterial species. Here, we report the identification five VIM metallo-β-lactamase-producing Alcaligenes faecalis isolates associated with a small outbreak large hospital Gaza, Palestine. Next-generation sequencing analysis showed bla VIM-2 is harbored by chromosomal genomic island among three strains, while VIM-4 carried...
Background The world is threatened by the ongoing emergence of carbapenem resistant organisms, which are contributing to increasing morbidity and mortality rates.The main objective this study was highlight resistance among clinical environmental Gram-negative bacteria (GNB) isolates.Methods A cross-sectional wherein 210 isolates, 150 swabs, 110 air samples were collected from three major hospitals in Gaza strip: Al-Shifa, AlNaser European hospitals.The lasted for seven months (September 2016...
Gastroenteritis is considered one of the leading causes morbidity and mortality in children especially developing countries. It a major childhood problem Gaza most common etiologic agents iron deficiency anemia (IDA).This study was conducted to investigate possible changes blood parameters that are associated with gastroenteritis infection among kindergarten Gaza.A cross-sectional case-control performed including suffering from matched healthy control group. Types etiological were identified...
Background: Infection is an important cause of death in burns. The emergence antimicrobial resistant pathogens like ESBL producers leading to inappropriate/or treatment failure and increased morbidity mortality.Objective: the purpose this study was determine susceptibility pattern with identification Extended spectrum Beta-lactamase (ESBL) among isolated from burn patients at Al-Shifa unit Gaza, Palestine.Methods: A total 40 gram-negative bacterial isolates were obtained wound Hospital...