A5015130343- Neonatal Respiratory Health Research
- Birth, Development, and Health
- Infant Nutrition and Health
- Pregnancy and preeclampsia studies
- Gestational Diabetes Research and Management
- Child Nutrition and Feeding Issues
- Ovarian function and disorders
- Neonatal and Maternal Infections
- Congenital Anomalies and Fetal Surgery
- COVID-19 Impact on Reproduction
- Breastfeeding Practices and Influences
- Reproductive Biology and Fertility
- Asthma and respiratory diseases
- Dental Health and Care Utilization
- Infant Development and Preterm Care
- Forensic Anthropology and Bioarchaeology Studies
- Congenital Diaphragmatic Hernia Studies
- Prenatal Screening and Diagnostics
- Child Nutrition and Water Access
- Respiratory and Cough-Related Research
- Maternal Mental Health During Pregnancy and Postpartum
- Genetic Mapping and Diversity in Plants and Animals
- Pharmaceutical studies and practices
- Liver Disease Diagnosis and Treatment
- Central Venous Catheters and Hemodialysis
Vita-Salute San Raffaele University
2025
Istituti di Ricovero e Cura a Carattere Scientifico
2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2025
University of Turin
2017-2024
Meyer Children's Hospital
2021-2023
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2020-2023
University of Milan
2008-2022
Aziende Socio Sanitaria Territoriale Rhodense
2022
University of Pavia
2009-2021
Sapienza University of Rome
2018
This was a nationwide prospective study carried out in Italy between 2005 and 2007, involving 34 centers with neonatal intensive care unit. The reports the Italian Neonatal Study charts for weight, length, head circumference of singletons born 23 42 gestational weeks, comparing them previous data most recent from European countries.Single live babies ultrasound assessment age within first trimester, both parents origin. Only fetal hydrops major congenital anomalies diagnosed at birth were...
The management of mother-infant dyads during the ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic constitutes a major issue for neonatologists. In mothers with SARS-CoV-2 infection, current recommendations suggest either to separate dyad or encourage protected rooming-in under appropriate precautions. No data are available regarding risk mother-to-infant transmission rooming-in.To evaluate postnatal from infected their neonates following and breastfeeding.A...
Extrauterine Growth Restriction (EUGR) refers to inadequate growth during hospitalization. Current definitions for EUGR are varied and can be classified as cross-sectional (weight at a given t-time <10th centile) or longitudinal loss between birth >1SD). Different t-times also considered in literature, such 36 weeks of gestational age (GA) discharge. The aim this study is investigate whether could predict the auxological outcome 24–30 months, evaluate agreement definitions. In total,...
Purpose: To describe optical coherence tomography (OCT) features of atypical congenital hypertrophy retinal pigment epithelium (CHRPE) associated with familial adenomatous polyposis (FAP). Methods: Case report. Results: A 34-year-old patient diagnosed FAP was referred to our clinic for fundus examination. We characterized the lesions we found using multimodal imaging (infrared, autofluorescence, OCT and widefield ultra-widefield image). described 3 possible stages progression in a single...
Introduction Real-world data on children with severe asthma is scarce. We report characteristics of already biologics, enrolled in the Severe Paediatric Asthma Collaborative Europe, a clinical research collaboration European Respiratory Society. Methods describe patient's including control assessed Global Initiative for (GINA) criteria, composite severity index (CASI), exacerbations, unscheduled medical attendances, lung function and quality life, biologic treatment because asthma. also...
The purpose of the study is to characterize rate progression geographic atrophy (GA) areas in patients with age-related macular degeneration (AMD) subclinical angioid streaks (AS), compared AMD without AS. This a retrospective, longitudinal, case–control study. Among cohort AMD, we selected GA AS and followed them for 2-year follow-up. An age- sex-matched control group secondary was selected. Demographics differences between two groups were analyzed. 60 eyes affected by 20 (mean age 82 ± 5...
We planned an observational study to address the clinical question: is twinning a risk factor for acute neonatal surgical intestinal disorders (PAIC)? Multicentric casecontrol studies appear most appropriate design among ones. The target population consists of preterm infants (gestational age <37 weeks). primary endpoint PAIC occurrence from birth hospital discharge: cases are neonates with PAIC, and controls without PAIC. Data will be collected records, extracting all randomly selecting...
We carried out genome-wide association (GWA) studies in inbred mouse strains characterized for their lung tumor susceptibility phenotypes (spontaneous or urethane-induced) with panels of 12,959 (13K) 138,793 (140K) single-nucleotide polymorphisms (SNPs). Above the statistical thresholds, we detected only SNP rs3681853 on Chromosome 5, two SNPs pulmonary adenoma 1 (Pas1) locus, and rs4174648 16 spontaneous incidence, urethane-induced multiplicity, respectively, 13K panel, but Pas1 locus 140K...
Fortification of human milk is a standard practice for feeding very low birth weight infants. However, preterm infants often still experience suboptimal growth and intolerance. New fortification strategies different commercially available fortifiers have been developed. Commercially are constituted by blend ingredients from sources, including plant oils bovine proteins, thus presenting remarkable differences in the quality macronutrients with respect to milk. Based on consideration that...
The aim of this study was to determine if Häävikko's maturation standards are applicable Italian children. sample included 500 healthy Caucasian children 3.9-15.4 years age: 267 girls [mean age 9.6 years, standard deviation (SD) 2.1] and 233 boys (mean 9.9 SD 2.1), living in Italy. All dental ages were assessed from panoramic films by one examiner using method. A second independently scored 48 evaluate the reproducibility measurements. good correlation (0.95) found, as shown Cohen's kappa....
This study was carried out to investigate growth indicators of fetal lean mass and fat in the second half gestational period pregnancies complicated by diabetes mellitus (GDM) comparison normal control pregnancies.Forty-three 171 GDM were followed longitudinally ultrasound examinations, measuring both traditional biometric parameters six non-traditional for evaluation mass. A mixed linear model derived from log-Count function used make comparisons between groups. Factor analysis evaluate...
Abstract Aim: To assess the effect of maternal age, height, early pregnancy body mass index (BMI) and ethnicity on birth weight. Subjects methods: A cross-sectional study was conducted more than 42,000 newborns. Ethnicity defined by country or, when missing (<0.6% records), citizenship. The characteristics weight evaluated with general linear models. Results: Maternal height BMI, although not significantly affected Among Italian babies, 4.7% newborns were classified as...
Objectives: The purpose of the present randomized controlled clinical trial was to compare use donkey milk–derived fortifier (DF) with commercial bovine (BF) in very preterm or very-low-birth-weight newborns, terms feeding tolerance. Methods: This included 156 newborns born at <32 weeks gestational age and/or a birth weight ≤1500 g. Newborns were 1:1 receive enteral either BF-arm, new, DF-arm for 21 days. fortification protocol same both study arms, and 2 diets designed be isoproteic...
In the context of suspected neonatal sepsis, early diagnosis and stratification patients according to clinical severity is not yet effectively achieved. this diagnostic trial, we aimed assess accuracy presepsin (PSEP) for supposedly septic neonates. PSEP, C-reactive protein (CRP), procalcitonin (PCT) were assessed at onset sepsis suspicion (T0), every 12–24 h first 48 (T1–T4), end antibiotic therapy (T5). Enrolled neonates stratified into three groups (infection, shock) Wynn Wong’s...
Importance Respiratory distress syndrome and feeding intolerance are common conditions that often associated with preterm infants. Showing similar efficacy, nasal continuous positive airway pressure (NCPAP) heated humidified high-flow cannula (HHHFNC) the most widespread noninvasive respiratory support (NRS) in neonatal intensive care units, but their effect on is unknown. Objective To evaluate of NCPAP vs HHHFNC high-risk infants syndrome. Design, Setting, Participants This multicenter...
Preterm birth (PTB) can be defined as the endpoint of a complex process that could influenced by maternal and environmental factors. Epigenetics recently emerged an interesting field investigation since it represents important mechanism regulation. This study evaluates epigenetic impact preterm on DNA methylation. Genome-wide DNAm was measured using Illumina 450K array in cord blood samples obtained from 72 full term 18 newborns. Lymphocyte composition calculated based specific markers are...
High serum day 3 FSH levels are associated with poor ovarian reserve and reduced fertility, but the interpretation of values according to age is still not univocal. The purpose this study was determine age-dependent reference in women regular menstrual cycles as a guide for specialists. performed at Department Mother–Infant University-based tertiary care centre. One-hundred ninety-two healthy normal menstruating were recruited study. All patients attended department on cycle blood sample...
Strategies to prevent anaemia in preterm infants include drawing fewer blood samples, the use of recombinant human erythropoietin and iron supplementation. Although sulfate is most commonly used pharmaceutical formulation for supplementation, there are few studies comparing different salts infants.This a study retrospective data comparison two groups receiving evaluate efficacy bisglycinate chelate sulfate.Three-hundred gestational age ≤32 weeks were enrolled: 225 supplemented with (3...
The magnitude of mother-to-infant transfer anti-SARS-CoV-2 antibodies through breast milk (BM) after maternal vaccination during breastfeeding, in the absence transplacental IgG, remains unclear. Here, we quantified anti-S and anti-RBD IgA, IgA1, IgA2 serum, saliva, BM, infant buccal swabs, feces up to 90 days second vaccine dose. BNT162b2 induced long-lasting IgG but weaker mucosal antibody production, with IgA amounts BM between 10- 150-fold lower compared serum. were exclusively IgA1...