A5052987605- Infant Nutrition and Health
- Neonatal Respiratory Health Research
- Cytomegalovirus and herpesvirus research
- Neonatal and Maternal Infections
- Neonatal Health and Biochemistry
- Breastfeeding Practices and Influences
- Infant Development and Preterm Care
- Herpesvirus Infections and Treatments
- Birth, Development, and Health
- Infant Health and Development
- Toxoplasma gondii Research Studies
- Parvovirus B19 Infection Studies
- Neonatal and fetal brain pathology
- Maternal Mental Health During Pregnancy and Postpartum
- Gut microbiota and health
- Pediatric health and respiratory diseases
- Congenital Heart Disease Studies
- Diet and metabolism studies
- Clinical Nutrition and Gastroenterology
- Metabolism and Genetic Disorders
- Respiratory Support and Mechanisms
- Congenital Diaphragmatic Hernia Studies
- Retinopathy of Prematurity Studies
- Inflammatory Bowel Disease
- Obesity, Physical Activity, Diet
Policlinico San Matteo Fondazione
2015-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2009-2021
Amsterdam UMC Location University of Amsterdam
2017
Emma Kinderziekenhuis
2017
Hospital Universitario 12 De Octubre
2017
Research Institute Hospital 12 de Octubre
2017
Ospedale Sant'Anna
2011
University of Pavia
1992-2010
Medica (Italy)
1993
Abstract Bronchiolitis is a common cause of hospitalization in infants. The long-lasting impact hygiene and social behavior changes during the pandemic on this disease debated. We investigated prevalence hospitalized cases, clinical severity, underlying risk factors before pandemic. study was conducted 27 hospitals Italy included infants for bronchiolitis following four periods: July 2018-March 2019, 2020-March 2021, 2021-March 2022, 2022-March 2023. Data demographics, neonatal gestational...
To clarify the links between parents' prenatal attachment and psychosocial perinatal factors such as maternal depression, anxiety social support.Cross-sectional study including 43 couples with high-risk pregnancy (RP) 37 physiologic (PP). Self-report measures (depression, anxiety, support attachment) are completed by mothers, questionnaire fathers.Depression (p < 0.001) state higher in RP. Both, paternal antenatal is significantly lower RP 0.001; p 0.005) but not related to depression or...
Abstract Background Fetal programming during in utero life defines the set point of physiological and metabolic responses that lead into adulthood; events happening “the first 1,000 days” (from conception to 2-years age), play a role development non-communicable diseases (NCDs). The infant gut microbiome is highly dynamic organ, which sensitive maternal environmental factors one elements driving intergenerational NCDs’ transmission. A.MA.MI (Alimentazione MAmma e bambino nei primi MIlle...
Abstract Purpose With the aim of characterizing gastrointestinal (GI) microbiota and contextually determine how different prenatal, perinatal, postnatal factors affected its composition in early childhood, infants were enrolled a longitudinal-prospective study named “A.MA.MI.” ( Alimentazione MAmma e bambino nei primi MIlle giorni ; NCT04122612, October 2019). Methods Forty-five fecal samples collected at 12 months infants’ age, identified as 3rd follow-up (T3). The evaluated variables...
Endocrine disruptors (EDCs) are chemicals that interfere with the endocrine system. EDC exposure may contribute to development of obesity, type 2 diabetes, and cardiovascular diseases by impacting composition an infant’s gut microbiota during first 1000 days life. To explore relationship between maternal urinary levels Bisphenol-A phthalates (UHPLC-MS/MS), infant (16S rDNA) at age 12 months (T3) and, retrospectively, birth (T0), 1 month (T1), 6 (T2), stool samples from 20 infants breastfed...
To measure the red cell distribution width (RDW) ranges at birth and to evaluate potential association with typical neonatal diseases: patent of ductus arteriousus (PDA), bronchopulmonary dysplasia (BPD), late-onset sepsis (LOS) mortality.Forty-six full-term, 41 preterm, 35 intrauterine growth restricted (IUGR) infants participated in this retrospective, observational study. RDW was measured before 3 days life (T0) all infants, first month (T1) preterm/IURG patients.RDW% mean (standard...
Early diagnosis of congenital toxoplasma infection is difficult to establish using serological methods. We explored specific T cell immunity Toxoplasma gondii antigens identify more accurate diagnostic tests for an early in newborns at risk toxoplasmosis.T lymphocyte proliferation, interferon (IFN)-gamma production and activation expression were evaluated 23 infected 65 uninfected neonates different times, the first year life.The immunologic accurately discriminated when tested <or=90 >90...
Forty breastfed full-term infants were randomly, double blind assigned to receive orally Lactobacillus reuteri (L. reuteri) DSM 17938, 5 drops/daily (108 colony-forming units), for 4 weeks (n = 20) or an identical placebo 20), starting before third day of life. They underwent basal and final visit monitor growth parameters gastrointestinal (GI) disease. Parents registered daily: crying minutes, stool frequency consistency, numbers regurgitations, adverse events. Secretory IgA (sIgA) has been...
Background Early life gut microbiota is involved in several biological processes, particularly metabolism, immunity, and cognitive neurodevelopment. Perturbation the infant’s increases risk for diseases early later life, highlighting importance of understanding connections between perinatal factors with microbial composition. The present research paper aimed at exploring prenatal postnatal influencing infant composition six months age. Methods Gut infants enrolled longitudinal, prospective,...
Importance Respiratory distress syndrome and feeding intolerance are common conditions that often associated with preterm infants. Showing similar efficacy, nasal continuous positive airway pressure (NCPAP) heated humidified high-flow cannula (HHHFNC) the most widespread noninvasive respiratory support (NRS) in neonatal intensive care units, but their effect on is unknown. Objective To evaluate of NCPAP vs HHHFNC high-risk infants syndrome. Design, Setting, Participants This multicenter...
NMR-based metabolomics was used to compare the metabolic urinary profiles of exclusively breast-fed term infants (n = 11) with those a double-blinded controlled trial 49 formula-fed newborns randomized receive either an infant formula enriched by functional ingredients 24) or standard 25). Anthropometric measurements and urine samples were taken at enrollment (within first month life), around 60 days life, end study period (average age 130 days). The examined in relation time diet strategy....
CD64 index and triggering receptor expressed on myeloid cells-1 are biomarkers neutrophil polymorphonuclear cells with crucial role in sepsis. The study aim is to assess diagnostic performance, individually combined, of (surface marker/soluble form), late-onset sepsis preterm infants.Observational study.Neonatal ICU.Sixteen septic 16 control infants, gestational age younger than 32 weeks and/or birth weigh less 1500 g.Seventy free were enrolled into the study. measured once between day 5 15...