A5008244920- Renal Diseases and Glomerulopathies
- Microstructure and Mechanical Properties of Steels
- Magnetic Properties and Applications
- Renal and Vascular Pathologies
- Cell Adhesion Molecules Research
- Enzyme Catalysis and Immobilization
- Shape Memory Alloy Transformations
- Genetic and Kidney Cyst Diseases
- Catalytic Processes in Materials Science
- Analytical Chemistry and Chromatography
- Monoclonal and Polyclonal Antibodies Research
- Catalysis and Oxidation Reactions
- Physics of Superconductivity and Magnetism
- Dialysis and Renal Disease Management
- Urban and spatial planning
- Metallurgy and Material Science
- Pancreatic function and diabetes
- Chronic Kidney Disease and Diabetes
- Structural Behavior of Reinforced Concrete
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Sleep and related disorders
- Magnetic properties of thin films
- Platelet Disorders and Treatments
- Sleep and Wakefulness Research
- Lung Cancer Treatments and Mutations
The University of Tokyo
1987-2024
Shonan Kamakura General Hospital
2018-2023
Toranomon Hospital
2019-2022
Penta-Ocean Construction (Japan)
2004-2020
Mitsubishi Materials (Japan)
1999-2020
Central Research Institute
2020
Osaka University
1987-2014
Kyushu University
1996-2011
Hokkaido University
1997
Waseda University
1986-1987
The enzymatic production of biodiesel through alcoholysis triglycerides has become more attractive because it shows potential in overcoming the drawbacks chemical processes. In this study, we investigate from crude, non-edible Jatropha oil and methanol to characterize Burkholderia cepacia lipase immobilized an n-butyl-substituted hydrophobic silica monolith. We also evaluate performance a lipase-immobilized monolith bioreactor continuous biodiesel.The used contained 18% free fatty acids,...
Introduction: Indications for sodium-glucose cotransporter-2 (SGLT2) inhibitors have expanded to include heart failure and chronic kidney disease after the year 2020. Whether how demographic trends in prescription of SGLT2 changed indication expansion not been studied extensively. Methods: This study is a descriptive analysis serial, cross-sectional data on nationwide between April 2016 March 2023 obtained from NDB Open Data Japan, which contains more than 95% total health insurance...
To understand sleep mechanisms and develop treatments for disorders, investigations using animal models are essential. The architecture of rodents differs from that diurnal mammals including humans non-human primates. Sleep studies have been conducted in primates; however, these assessments were performed on animals placed a restraint chair connected via the umbilical area to recording apparatus. avoid restraints, cables, other stressful apparatuses manipulations, telemetry systems...
Electrochromic characteristics of familiar organic materials with relatively simple molecular structures, such as dimethyl terephthalate, are described. Coloration occurred at the cathode all cells examined; color spontaneously bleached upon removing voltage. Electrochemically induced optical absorption was measured for compounds various types terminal groups. As a result, found to depend type groups well its position placed in compound. The time response density during coloration and...
ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTAdsorption of Hexachloroplatinate Complex on Au(111) Electrode. An in Situ Scanning Tunneling Microscopy and Electrochemical Quartz Microbalance StudyKohei Uosaki, Shen Ye, Yasuhiro Oda, Toshio Haba, Kei-ichi HamadaView Author Information Physical Chemistry Laboratory, Division Chemistry, Graduate School Science, Hokkaido University, Sapporo 060, JapanCite this: Langmuir 1997, 13, 3, 594–596Publication Date (Web):February 5, 1997Publication History...
Microbioreactors are effective for high-throughput production of expensive products from small amounts substrates. Lipases versatile enzymes chiral syntheses, and highly activated when immobilized in alkyl-substituted silicates by the sol-gel method. For practical application lipases to a flow system, microbioreactor loaded with macroporous silica monolith is well suited, because it can be easily integrated chromatographic separator optical resolution. We attempted develop containing...
AbstractThe objective of this study was to produce biodegradable poly(lactide-co-glycolide) (PLGA; 50/50) microspheres by an oil-in-oil (o/o) solvent evaporation method prolong the in vitro release ovalbumin (OVA) as a model protein. The effects, on loading efficiency, microsphere yield, morphology and drug release, two dispersing agents, aluminum tristearate Span 80, mineral oil were examined. PLGA 50/50 containing OVA powder (sieved through 53 μm mesh) prepared using o/o method. When...
The most widely used animal models to develop sleep-disorder drugs are rodents, particularly rats and mice. However, unlike humans, these rodents nocturnal. Thus, diurnal non-human primates represent a valuable more translational model study sleep. Although have been screened in primates, the use of telemetry system is not desirable method for rapid drug efficacy assessment because need expensive equipment, complicated surgery, long time before results can be obtained from analysis by...
Abstract BACKGROUND: Sol–gel entrapment of lipases is usually performed in an aqueous solution. A novel method sol–gel coating lipase supercritical carbon dioxide (SC‐CO 2 ) proposed. RESULTS: Crude powder ( Rhizopus oryzae coated with hydrophobic silicates, derived from dimethyldimethoxysilane and tetramethoxysilane SC‐CO at 35 °C 15 MPa, exhibited 5–7 times higher esterification activity than that prepared via route. Lipase immobilized a methyl‐substituted silica monolith was also highly...
Pseudoelastic behaviour of Fe-23.8at%Ga single crystals compressed with different loading axes at room temperature was examined focusing on the activated deformation mode. In crystals, {101}<111> slip and {211}<111> twin were mainly depending axis. depended strongly If operative, sole paired 1/4<111> superpartial dislocations moved dragging antiphase boundaries (APB). During unloading, APB pulled back superpartials due to its tension resulting in pseudoelasticity. contrast, twinning...
e14110 Background: ICIs such as anti-PD-1/-L1 Inhibitor and anti-CTLA-4 have been used in many types of cancer, irAEs occur a considerable proportion patients. Predictive biomarkers could help us to manage promptly. Methods: We retrospectively analyzed the consecutive patients treated with nivolumab, pembrolizumab, atezolizumab or ipilimumab, not investigational drugs, between March 2015 December 2018 based on electric medical records our institution. evaluated relationship clinical...
In a demonstration plant for the recycling of post-use electric home appliances, authors developed primary disassembly process an air conditioner and washing machine. The purpose is to collect CFCs (chlorofluorocarbons) separate heat exchangers compressor. This employed by image processing system robotic automatic cutting system. It can disassemble with work efficiency 17 units per hour. machine motor. in which depth tank measured automatically supersonic wave sensor. 27