A5107944077- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Neurological Disease Mechanisms and Treatments
- Ferroptosis and cancer prognosis
- Pharmacological Effects of Natural Compounds
- Traumatic Brain Injury and Neurovascular Disturbances
- Cancer, Lipids, and Metabolism
- Immune cells in cancer
- Advanced Breast Cancer Therapies
- Cancer-related Molecular Pathways
- Cancer Mechanisms and Therapy
- Acute Ischemic Stroke Management
- Mycobacterium research and diagnosis
- Cancer-related gene regulation
Army Medical University
2023-2025
Yunnan University
2025
Yunnan University of Traditional Chinese Medicine
2021-2023
Abstract SFTA1P is a pseudogene-derived lncRNA and has become master regulator in tumor carcinogenesis progression processes. been reported as potential diagnostic prognostic biomarker non-small cell lung cancer (NSCLC). The down-regulation of tissue associated with poor prognosis, however, the detailed molecular mechanism biological functions still need to be investigated. We demonstrated that inhibited growth metastasis NSCLC vitro vivo. played dual cytoplasm nucleus: cytoplasm, can serve...
The KunMingShanHaiTang Formula (KMSHTF), adjusted by Professor Zhong Chuanhua for the treatment of ulcerative colitis (UC), is work a renowned veteran practitioner Chinese medicine. However, its specific mechanism remains unknown. Consequently, it intriguing to investigate molecular which KMSHTF treats UC. To elucidate in UC rats. Initially, active ingredients and key target genes treating were analyzed using network pharmacology. Protein-Protein interaction gene enrichment analyses...
Cyclin-dependent kinases (CDKs) are hyperactive in many cancers and have served as cancer therapeutic targets for decades. Palbociclib (Palb) is the first approved CDK4/6 inhibitor to treat hormone receptor (HR)-positive, HER2-negative advanced breast cancer. Acquired drug resistance one obstacle of Palb be utilized other CDK2 compensation loss causes that cells resistant Palb. Hence, targeting multiple CDKs could a novel strategy prevent expand application In this study, we initially...
Hepatocellular carcinoma (HCC) is a frequently occurring malignant gastrointestinal cancer. The 5-year survival rate of HCC still below 8%, and thus, identifying more effective therapeutic methods needed. Here, we evaluated the effects Stigmast-4-en-6β-ol-3-one (S463) on viability colony formation liver cancer cells. S463 treatment decreased induced apoptosis ferroptosis in cells, also increased cellular malondialdehyde (MDA) lipid peroxidation levels. In treated expression level Bax was...
<ns3:p><ns3:bold>Background: </ns3:bold>Middle cerebral artery occlusion (MCAO) ischemia-reperfusion in rats is a commonly used <ns3:italic>in vivo</ns3:italic> model stroke research, but the problems of long time-consuming, unstable neurological injury and high mortality are not conducive to an experimental animal study. In this study, success rate MCAO was improved by changing surgical approach giving preoperative as well postoperative care support.<ns3:bold> </ns3:bold></ns3:p><ns3:p>...