A5000991231- Inflammatory mediators and NSAID effects
- Colorectal Cancer Treatments and Studies
- Ovarian cancer diagnosis and treatment
- Cancer, Lipids, and Metabolism
- Epilepsy research and treatment
- Histiocytic Disorders and Treatments
- Dermatological and COVID-19 studies
- Gestational Trophoblastic Disease Studies
- Colorectal Cancer Screening and Detection
- Global Cancer Incidence and Screening
- Intraperitoneal and Appendiceal Malignancies
- Viral-associated cancers and disorders
- Eicosanoids and Hypertension Pharmacology
- Health Systems, Economic Evaluations, Quality of Life
- Advanced Breast Cancer Therapies
- Nursing Diagnosis and Documentation
- Cancer Treatment and Pharmacology
- Bone and Joint Diseases
- Anesthesia and Sedative Agents
- Lymphoma Diagnosis and Treatment
- Hip and Femur Fractures
- Health Education and Validation
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hematological disorders and diagnostics
- Cancer Risks and Factors
School District of Palm Beach County
2024
Merck & Co., Inc., Rahway, NJ, USA (United States)
2023-2024
Mount Sinai Medical Center
2023
Imperial College London
2023
University College London
2014-2020
MRC Clinical Trials Unit at UCL
2015-2020
Queen Alexandra Hospital
2020
Imperial College Healthcare NHS Trust
2018
National Health Service
2018
Charing Cross Hospital
2018
There is a considerable body of pre-clinical, epidemiological and randomised data to support the hypothesis that aspirin has potential be an effective adjuvant cancer therapy.
Combination antiretroviral therapy (cART) is standard of care for patients with HIV diagnosed Kaposi's sarcoma (KS), but the current role systemic chemotherapy undefined.Since 1998, a prospective stage-stratified approach has been adopted 469 KS. Patients early-stage (T0) KS are treated cART alone; advanced-stage (T1) receive plus liposomal anthracycline chemotherapy. Clinical characteristics, overall survival, and progression-free survival were analyzed according to stage at presentation...
OBJECTIVES: Accumulating basic science data, early clinical findings and various feasibility considerations have provided rationales for administering ketamine as a proposed rescue medication midazolam-resistant status epilepticus (SE) in the logistically challenging prehospital environment. This report details multiyear experience of paramedics managing SE following introduction ketamine-rescue protocol. DESIGN: A 7-year, population-based, observational study was conducted to evaluate...
The population in developed countries is ageing. Cancer a disease of ageing, and this likely to lead an increase the number older patients diagnosed with cancer significant implications for resource allocation research priorities. Breast women presents challenges.This paper describes trends new breast registrations over last 38 years.Data were extracted from Office National Statistics describing aged 65 or over, 1971 2009.The diagnoses across all age groups increased 17,694 40,260 2009....
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Erythema nodosum is often associated with a distressing symptomatology, including painful subcutaneous nodules, polyarthropathy, and significant fatigue. Whilst it well-documented side-effect of estrogen therapy in females, we describe what believe to be the first report literature erythema as result male. A 64-year-old Afro-Caribbean man locally advanced carcinoma prostate agreed participate randomized controlled trial comparing patches luteinizing hormone-releasing hormone analogs achieve...
TPS1617 Background: Pre-clinical data demonstrate that aspirin inhibits tumour growth and prevents metastases. Meta-analyses of individual patient from randomized trials evaluating cardiovascular (CV) effects show reduced metastases cancer deaths for those on aspirin. Toxicity concerns have limited use as a primary anti-cancer prevention agent. In the adjuvant setting, risk:benefit ratio differs, with higher morbidity mortality recurrence potentially outweighing risks. Aspirin, an...
<h3>Introduction/Background</h3> In every woman with a hydatidiform mole pregnancy hCG-levels will be monitored after evacuation. If persist or relapse normalization gestational trophoblastic neoplasia (GTN) is diagnosed and chemotherapeutic treatment required. <h3>Purpose</h3> Following evacuation of complete (CHM), the relative risk malignant change hCG uncertain. Here we examine this question in large national data-set. <h3>Methodology</h3> All registered cases CHM Charing Cross Hospital...
Background: Red blood cells (RBC) and platelets affect the coagulation capacity in bleeding thrombotic disorders.The ( patho)physiology of interactions manifest thrombin generation (TG) process.Aims: To redefine cell contributions to clotting process.Methods: Using a new calibrated method, we directly compared TG whole platelet-rich plasma (PRP).Results: We report faster initially higher shorter time than PRP upon low concentrations coagulant triggers, including tissue factor, Russell's...