A5045589184- Urinary Bladder and Prostate Research
- Pelvic floor disorders treatments
- Urinary Tract Infections Management
- Advanced Radiotherapy Techniques
- Bladder and Urothelial Cancer Treatments
- Gut microbiota and health
- Urological Disorders and Treatments
- Circadian rhythm and melatonin
- Prostate Cancer Treatment and Research
- Ureteral procedures and complications
- Diet and metabolism studies
- Radiomics and Machine Learning in Medical Imaging
- Prostate Cancer Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Clostridium difficile and Clostridium perfringens research
- Pelvic and Acetabular Injuries
- Advanced Glycation End Products research
- Urinary and Genital Oncology Studies
- Polyomavirus and related diseases
- Cancer survivorship and care
- Mobile Health and mHealth Applications
- Colorectal Cancer Treatments and Studies
- Management of metastatic bone disease
- Hormonal Regulation and Hypertension
- Physical Activity and Health
University of the Ryukyus
2017-2025
National Hospital
2022
University of the Ryukyus University Hospital
2019
Seoul Medical Center
2018
Royal Oak Community Coalition
2017
Tokyo Medical Center
2011-2012
National Hospital Organization
2011
Abstract This study aimed to investigate the long‐term physiological and morphological changes in bladders of diabetic rats. Sixty‐nine female Sprague–Dawley rats were divided into a control six (3 days 2, 4, 8, 12, 24 weeks after induction type 1 diabetes) groups. Metabolic cages cystometry used evaluate bladder function. Bladder contractility was assessed using an organ bath test, Masson's trichrome staining performed. In metabolic cage study, urination frequency during dark period...
In this study, we evaluated the prevalence of lower urinary tract symptoms and associated clinical features in patients with chronic stroke.Patients stroke who had been regularly followed up at general medical hospitals Okinawa, Japan were enrolled study. The asked to complete a self-reported questionnaire regarding their physical activity, history, core symptom score (CLSS) questionnaire, anonymity. association between each disturbance category characteristics such as age, gender,...
Abstract Objective Collagen and elastin are the main components of female pelvic tissue. We investigated whether single nucleotide polymorphisms (SNPs) collagen type 1 alpha (COL1A1), 3 (COL3A1), lysyl oxidase-like (LOXL) 4 were associated with onset organ prolapse (POP) in Japanese women. Fifty-two women POP 28 without included. SNPs identified using TaqMan® SNP genotyping assay. Results Age, parity, lower urinary tract symptoms significantly higher group than control group. The prevalence...
To confirm changes in urethral activity with age, both intravesical pressure and perfusion (UPP) were recorded external sphincter electromyography (EUS-EMG) was performed. A total of 33 female Sprague Dawley rats aged 3 months (young rats), 12 (middle-aged 24 (aged rats) used. Bladder evaluated using continuous cystometry. Urethral by simultaneously recording UPP isovolumetric conditions under urethane anesthesia each group. Additionally, EUS-EMG monitored the same conditions. In cystometry,...
Numerous studies have revealed distinct differences in the profiles of gut microbiota between non-obese and obese individuals. To date, however, little is known if any disparities community exist metabolically healthy (MHO) unhealthy (MUO) subjects. We therefore aimed to comprehensively characterize circulating metabolites serum from both MHO MUO residing remote island, Kumejima, where prevalence obesity one highest Japan, explored possible correlations profile markers metabolic syndrome....
Aims We aimed to investigate the age‐associated changes in movement coordination between urinary bladder and urethra rats. Methods A total of 17 female Sprague‐Dawley rats were used. The divided into young (3 months old) middle‐aged (12‐15 groups. In both groups, isovolumetric cystometry urethral perfusion pressure (UPP) measurements performed under urethane anesthesia. After rhythmic contractions stabilized, L‐arginine, a nitric oxide (NO) substrate (100 mg/kg), was administered...
Abstract Aim To validate a novel digital health monitoring system to measure the volume of voided urine. Methods Micturition was calculated using our self‐health urine excretion (s‐HMSU) in 18 participants (16 women and 2 men; average age, 40.8 years), without history voiding symptoms. Participants completed self‐reported questionnaire regarding their medical water intake during period observation, as well Core Lower Urinary Tract Symptom Score (CLSS) questionnaire. assess reliability...
To evaluate the effect of a mobile digital intervention on voiding patterns, we performed 24-h voided volume monitoring in individuals with metabolic disorders.Participants disorders were grouped into either group (n = 17), who had access to smartphone app (CARADA), or non-intervention 11), did not. Urine was conducted for 24 h using novel self-health system urine excretion (s-HMSU). Body weight, abdominal circumference, blood pressure, and biomarkers measured.Physical findings test results...
Aims We examined the efficacy of tramadol on urethral reflex during sneezing, as well role µ‐opioid receptors in spinal cord, rats. Methods Forty‐one female Sprague‐Dawley rats were used. The divided into normal and with vaginal distension (VD), which mimics stress urinary incontinence (SUI) humans. Under urethane anesthesia, sneeze‐induced amplitude responses (AUR) baseline pressure (BP) after intravenous injection using a microtransducer‐tipped catheter both rat groups. effect intrathecal...
Abstract Numerous studies have revealed distinct differences in the profiles of gut microbiota between non-obese (NO) and obese (OB) individuals. To date, however, little is known if any disparities community exist metabolically healthy (MHO) unhealthy (MUO) subjects. We therefore aimed to comprehensively characterize circulating metabolites serum from both MHO MUO residing remote island, Kumejima, where prevalence obesity one highest Japan, explored possible correlations profile markers...
(症例1) 患者は82歳，男性．2000年に根治的腎摘除術を施行し経過を見ていたが，2005年に肺転移が出現し免疫療法を実施した．2008年6月に膵，骨転移を認めソラフェニブ400 mg/日，NSAIDsを開始した．2009年10月，癌性疼痛が増悪し第4腰椎に放射線照射30 Gyを施行したが著効しなかった．同年12月，疼痛管理目的に入院中に嘔吐，腹痛を認めCT施行し，腹腔内にfree airを認め消化管穿孔と診断した．経鼻胃管留置及び抗生剤投与にて保存的に軽快した． (症例2) 患者は62歳，男性．術前に肺転移を認めた腎細胞癌に対し2006年12月に根治的腎摘除術施行し，直後より免疫療法を開始した．2008年7月にソラフェニブ800 mg/日を開始し一旦は転移巣縮小したが，2010年1月より転移巣が増大しスニチニブ50 mg/日に変更した．10月に胸水貯留を認め入院した．胸水ドレナージにて加療中，突然の上腹部痛を認めCT施行，腹腔内にfree...
Objective To report a multicenter experience with the management of urachal abscess treatment in Japan. Methods This was retrospective study 263 cases managed at 12 university hospitals Kyushu–Okinawa region over 10‐year period. Age, sex, size, clinical symptoms, type remnants, and were collected analyzed. Results The average age 29.8 ± 18.1 years, males accounting for approximately two‐thirds population. size 1.7 cm (range 0–11 cm). most common presenting symptom umbilical secretion (66%),...
You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Basic Research & Pathophysiology II1 Apr 2018MP38-02 AGE-ASSOCIATED CHANGES OF NITRIC OXIDE-MEDIATED URETHRAL SMOOTH MUSCLE RELAXATION AND EXTERNAL SPHINCTER FUNCTION IN RATS Takuma Oshiro, Minoru Miyazato, Ryu Kimura, Asuka Ashikari, and Seiichi Saito OshiroTakuma Oshiro More articles by this author , MiyazatoMinoru Miyazato KimuraRyu Kimura AshikariAsuka Ashikari SaitoSeiichi View All...
We investigated the changes in bladder and urethral function after cerebral infarction (CI) influence of tramadol on these functions.Twenty-eight female Sprague Dawley rats were divided into normal CI groups. In awake condition, metabolic cage study blood pressure evaluated. Under urethane anesthesia, intravenous effect (0.01-1 mg/kg), which has both µ-opioid receptor stimulation inhibition norepinephrine serotonin reuptake, continuous cystometry, simultaneous measurements perfusion (UPP)...
You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Basic Research & Pathophysiology II1 Apr 2016MP68-11 URETHRAL DYSFUNCTION IN AGING RATS Ryu Kimura, Takuma Oshiro, Asuka Ashikari, Minoru Miyazato, and Seichi Saito KimuraRyu Kimura More articles by this author , OshiroTakuma Oshiro AshikariAsuka Ashikari MiyazatoMinoru Miyazato SaitoSeichi View All Author Informationhttps://doi.org/10.1016/j.juro.2016.02.1348AboutPDF ToolsAdd to...