A5077045828- Insect Pest Control Strategies
- Insect Utilization and Effects
- Insect Resistance and Genetics
- Insect and Pesticide Research
- Immune Cell Function and Interaction
- Insect-Plant Interactions and Control
- Neurobiology and Insect Physiology Research
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
- Agricultural Practices and Plant Genetics
- Entomopathogenic Microorganisms in Pest Control
- Agricultural pest management studies
- Immune cells in cancer
- Insect and Arachnid Ecology and Behavior
- Insect symbiosis and bacterial influences
- Seaweed-derived Bioactive Compounds
- MicroRNA in disease regulation
- Plant and Fungal Interactions Research
- Extracellular vesicles in disease
- Dengue and Mosquito Control Research
- Forensic Entomology and Diptera Studies
- Adenosine and Purinergic Signaling
- Plant Disease Resistance and Genetics
- Genomics, phytochemicals, and oxidative stress
- Phytochemicals and Medicinal Plants
Anhui Agricultural University
2016-2025
Shanghai Jiao Tong University
2022-2023
Shanghai First People's Hospital
2022-2023
Sichuan University
2022
State Key Laboratory of Oral Diseases
2022
Shanghai University of Traditional Chinese Medicine
2018
Shanghai Blood Center
2013-2016
Institute of Plasma Physics
2008
Chinese Academy of Sciences
2008
Insect pests negatively affect crop quality and yield; identifying new methods to protect crops against insects therefore has important agricultural applications. Our analysis of transgenic Arabidopsis thaliana plants showed that overexpression pentacyclic triterpene synthase 1, encoding the key biosynthetic enzyme for natural plant product (3E)-4,8-dimethyl-1,3,7-nonatriene (DMNT), led a significant resistance major insect pest, Plutella xylostella. DMNT treatment severely damaged...
The occurrence of colorectal cancer (CRC) is associated with a variety factors. Accumulating evidence shows that peripheral differentiation regulatory T cells (Tregs) critical in controlling tumorigenesis. Our previous studies demonstrated the Yi-Yi-Fu-Zi-Bai-Jiang-San (YYFZBJS) extract exerted potent anticancer activities by significantly enhancing immunosuppression ApcMin/+ mice. However, there limited knowledge on effect YYFZBJS prevention and underlying mechanisms action.In this study,...
Rho GTPase activating protein 9 (ARHGAP9), a member of RhoGAP family, has been identified as for Cdc42 and Rac1. Here, we aimed to clarify the expression functional role ARHGAP9 in hepatocellular carcinoma (HCC). By analyzing TCGA (The Cancer Genome Atlas) LIHC (liver carcinoma) database, found that was lower HCC tissues than normal liver tissues, patients with had significant shorter overall survival time those higher expression. Cell counting kit-8 (CCK-8), transwell assays vivo...
Abstract Our bioassays reviewed that antennae played crucial roles in the responses of maize weevil ( Sitophilus zeamais ) to food and sex volatiles. In order identify odorant‐binding protein (OBP) genes, we analyzed its antennal transcriptome. total, 21,587,928 high‐quality clean reads were obtained from RNA‐seq, 52,206 unigenes assembled, 25,744 showed significant similarity E value < 10 −5 known proteins NCBI nonredundant database. From those unigenes, identified 41 candidate OBP...
Background: Recent studies have demonstrated the contribution of non-coding RNAs (ncRNAs) to neuropathic pain. However, expression profile ncRNAs in trigeminal ganglion (TG) and their functional mechanism underlying pain are still unclear. Methods: In present study, model induced by chronic constriction injury infraorbital nerve (CCI-ION) was used study potential regulatory miRNAs, lncRNAs, circRNAs, mRNAs TG RNA-sequencing (RNA-seq) bioinformatics analysis. CCI-ION mice suffered from...
Odorant-degrading enzymes (ODEs) play an important role in rapidly degrading and inactivating odorant molecules that have completed information transmission, as well maintaining the stability sensitivity of insect olfactory sensing systems. Glutathione S-transferases (GSTs), a group ODEs, supposedly bear ability to catalyze conjugation glutathione (GSH) xenobiotic process. However, there are few reports regarding GST genes Sitophilus zeamais Thus, we characterized 13 full-length encoding...
The anti-EGFR antibody cetuximab is used as a first-line targeted therapeutic drug in colorectal cancer. It has previously been reported that the efficacy of EGFR limited by emergence acquired resistance. In our previous study transmissibility effect exosomes from resistant tumor cells to sensitive was identified. can therefore be hypothesized might affect neighboring and distant via regulation exosome composition behavior. However, mechanism KRAS-wild-type cancer (CRC) remains unknown....
The lepidopteran crop pest Plutella xylostella causes severe constraints on Brassica cultivation. Here, we report a novel role for RPX1 (resistance to P. xylostella) in resistance this Arabidopsis thaliana. rpx1-1 mutant repels larvae, and feeding the severely damages peritrophic matrix structure midgut of thereby negatively affecting larval growth pupation. This results from accumulation defence compounds, including homoterpene (3E)-4,8-dimethyl-1,3,7-nonatriene (DMNT), due upregulation...
Odorant-binding proteins (OBPs) are important in insect chemical communication. The objective of this research was to identify the functions two OBPs Sitophilus zeamais. qRT-PCR and western blot (WB) were performed investigate expression profiles at transcript protein levels, respectively. Fluorescence competitive binding assays used measure ability bind host volatiles, a Y-tube olfactometer verify results (attraction/no response) via behavioral experiments. RNAi function by knocking down...
This paper reported the immunnodulation tests of Eupolyphaga sinensis Walker in immunity. Mice were fed with E. water-decoction at a dose 1.89, 3.78 and 7.56 g/kg/d for 4 weeks, then their immune function was studied. The results effects on spleen index, thymus index carbon expurgation experiments mice, indicated that did not affect visceral index, but enhanced observably expurgatory phagocytic index. could stimulate response delayed hypersensitivity. proliferation concanavalin A...
In order to take full advantage of Tenebrio molitor larvae (yellow mealworm) resources, the supercritical CO2 fluid freeze-dried powder T. (fdTML) extraction on immune systems mice was carried out. The results about effects fdTML carbon expurgation and phagocytosis peritoneal macrophages experiments indicated that enhanced observably expurgatory index, phagocytic rate index. could stimulate response delayed hypersensitivity. proliferation ConA-induced mitogenic reponse for spleen lymphocyte...
Abstract During Bt transgenic rice storage, Cry1Ab/Cry1Ac fused protein is exposed to the maize weevil Sitophilus zeamais and parasitoid wasp Theocolax elegans . We have carried out a long-term risk assessment for these non-target organisms in storehouse. Effects of on S T been carefully detected laboratory experiment over 5 years. The survival, development, fecundity, longevity were compared between non- treatments every generations from generation 1 25. Moreover, adult body size sex ratio...
The density and composition of lymphocytes infiltrating colon tumors serve as predictive factors for the clinical outcome cancer. Our previous studies highlighted potent anti-cancer properties principal compounds found in
The fall armyworm (FAW), Spodoptera frugiperda , is a highly polyphagous lepidopteran pest, with its growth and adaptation affected by different host plants. However, little known about the effects of plants on ovarian development in this species. Thus, we evaluated feeding corn ( Zea mays L. ) goosegrass Eleusine indica ), S. . Using various stages also larval pupal weights, number eggs, differentiation ovarioles over time. Results showed that females fed had shorter laid less eggs than...
Behavioral responses of S. zeamais to odours from pulverized wheat, brown rice, sorghum, buckwheat, peanut and cork were compared in a Y-tube-olfactometerbioassay. Results showed that both sexes responded host volatiles males more sensitive than females. The strongest grains wheat rice found, insects reared on these dramatically heavier other tested materials (grain cork). Multiple-choices tests, which removed the within different minutes simultaneously presented chamber, used study whether...
Sensory neuron membrane proteins (SNMPs) play an important role in pheromone detection and are considered a component of reception insects. However, the SNMPs Sitophilus zeamais Motschulsky, pest stored cereals, have not previously been reported. In this study, we report four (named SzeaSNMP1a, SzeaSNMP1b, SzeaSNMP2a, SzeaSNMP2b) from antennal transcriptome adult S. zeamais, including their full-length open reading frames. Sequence alignment phylogenetic analysis suggest that these SzeaSNMPs...
The novel HLA ‐A*02:06:13 allele shows one nucleotide difference from A *02:06:01 in exon 4 at position 657 ( T → C ).
A novel HLA-DRB1 allele, DRB1*13:26:02, has been identified by sequence-based typing in a Chinese individual.
This paper describes the results of experiments to test effect larvae Tenebrio molitor Linnaeus on immune systems mice. Mice were given a decoction T. in water at doses 1.87, 3.75 and 7.50 g/kg/d for four weeks, after which their function was studied. The indicate that observably enhanced carbon expurgatory index phagocytic index. half hemolysis values serum treated mice increased compared control group. Furthermore, nitric oxide (NO) content all treatment groups higher than group whereas...