- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
- Macrophage Migration Inhibitory Factor
- Monoclonal and Polyclonal Antibodies Research
- Immune Response and Inflammation
- Wheat and Barley Genetics and Pathology
- Cancer-related molecular mechanisms research
- Proteoglycans and glycosaminoglycans research
- Plant Disease Resistance and Genetics
- Molecular Biology Techniques and Applications
- RNA modifications and cancer
- Plant Pathogens and Resistance
- Galectins and Cancer Biology
- Hematopoietic Stem Cell Transplantation
- CAR-T cell therapy research
- Forensic and Genetic Research
- RNA Research and Splicing
- Glycosylation and Glycoproteins Research
- Systemic Lupus Erythematosus Research
- Immunodeficiency and Autoimmune Disorders
Zhejiang University
2024
Shanghai Blood Center
2004-2018
Shanghai Public Security Bureau
2004
A novel human leukocyte antigen-A (HLA-A) allele, A*0278, has been identified in a Chinese family using DNA-based typing and molecular cloning methods. The alleles A*0278 differs from its closest matching HLA sequence of A*0256 by silent substitution at 102 > C two replacement substitutions, 98T 292 G exon 2, resulting change codon 33 Phe (TTC) to Tyr (TAC) 98 His (CAC) Asp (GAC). Serology study revealed that is associated with HLA-A2 broad specificity. polymerase chain...
Abstract: The purpose of this study was to investigate the genetic polymorphisms and haplotypes microsatellite locus in exon 5 MICA gene intron 1 MICB human leukocyte antigen‐B ( HLA‐B ) based on 106 samples Guangzhou Han population through means polymerase chain reaction fluorescent technique (6‐FAM). corresponding haplotype frequencies, linkage disequilibrium values relative were estimated data. results show that genotype distributions satisfy Hardy–Weinberg equilibrium. In total, five...
The novel HLA ‐A*02:06:13 allele shows one nucleotide difference from A *02:06:01 in exon 4 at position 657 ( T → C ).
A novel HLA-DRB1 allele, DRB1*13:26:02, has been identified by sequence-based typing in a Chinese individual.
The newly detected HLA ‐B*40:210 allele has two nucleotide changes in exon 2 compared to B*40:49 allele.
HLA ‐B*40:211 allele differs from ‐B*40:02:01 by an amino acid exchange at position 132, which has a missense mutation in exon 3 Ser to Tyr.
The HLA‐DRB1*120204 allele differs by a single synonymous nucleotide change from the DRB1*120201 at position 203 in exon 2 C to G.
HLA ‐A*11:125 allele differs from A*11:01:01 by one nucleotide substitution at nt 140 T to C.
Two nucleotide changes in codon 77 ( ACC → AAT ) of HLA‐DRB1 *14:05:03 result the allele, *14:127:01 .
The novel HLA-B*40:229 allele shows one nucleotide difference from B*40:02:01 in exon 2 at position 97 (C → T).
Abstract Chinese cabbage ( Brassica rapa L. syn. B. campestris L., AA, 2n=20) is highly popular green leafy vegetable in the triangle of U, with China serving as its primary center origin and diversification. Plant height, rosette leaf diameter, disease resistance have always been important selection criteria for cabbage. In this study, we conducted re-sequencing on 55 accessions collected from China, Japan Korea, followed population genetic evolutionary analysis genome-wide association...
The HLA-B*55:57 allele differs from HLA-B*55:02:01:01 by one nucleotide substitution at position 535.