A5008241117- Pain Mechanisms and Treatments
- Neuropeptides and Animal Physiology
- Dental materials and restorations
- Ion channel regulation and function
- Nerve injury and regeneration
- Dental Implant Techniques and Outcomes
- Dental Radiography and Imaging
- Adenosine and Purinergic Signaling
- Temporomandibular Joint Disorders
- Neuroscience and Neuropharmacology Research
- Nicotinic Acetylcholine Receptors Study
- Cancer, Stress, Anesthesia, and Immune Response
- Laser Applications in Dentistry and Medicine
- Ion Channels and Receptors
- Dental Erosion and Treatment
- Bone Metabolism and Diseases
- Myofascial pain diagnosis and treatment
- Botulinum Toxin and Related Neurological Disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Connexins and lens biology
- Electrospun Nanofibers in Biomedical Applications
- Mesenchymal stem cell research
- Cancer-related molecular mechanisms research
- Neuroscience of respiration and sleep
- Orthodontics and Dentofacial Orthopedics
Sichuan University
2016-2025
State Key Laboratory of Oral Diseases
2016-2025
National Clinical Research Center for Digestive Diseases
2021-2025
Stomatology Hospital
2017-2024
West China Hospital of Sichuan University
2023-2024
Nanjing Tech University
2022
Zhaoqing University
2022
National Clinical Research
2017
Chengdu University
2017
Nippon Dental University
2011-2015
To measure the surface loss of dental restorative zirconia and short-term bond strength between an indirect composite resin (ICR) ceramic after various sandblasting processes.Three hundred bars were randomly divided into 25 groups according to type performed with pressures 0.1, 0.2, 0.4 0.6 MPa, times 7, 14 21 seconds, alumina powder sizes 50 110 µm. The control group did not receive sandblasting. volume height on shear (SBS) sandblasted ICR 24-h immersion measured for each using...
In this study, a novel dental composite based on the unsaturated bismethylene spiroorthocarbonate expanding monomer 3,9-dimethylene-1,3,5,7-tetraoxa-spiro[5,5]undecane (BMSOC) and bisphenol-S-bis(3-meth acrylate-2-hydroxypropyl)ether (BisS-GMA) was prepared. CQ (camphorquinone) of 1 wt % DMAEMA (2-(dimethylamino)ethyl methacrylate) 2 were used in photoinitiation system to initiate copolymerization matrix resins. Distilled water contact angle measurements performed for wettability...
We evaluated the correlation between oral health-related quality of life (OHRQoL) and Helkimo clinical dysfunction index (HDI) in patients with temporomandibular joint osteoarthritis (TMJ OA). Clinical data scores for Chinese version 14-item Oral Health Impact Profile (OHIP-C14) were recorded analyzed 541 TMJ OA. Each patient was assigned an HDI score 1 to 25, which used classify severity into three categories. OHRQoL assessed by using OHIP-C14 score, ranged from 0 56. Both significantly...
Abstract Inflammatory orofacial pain, in which substance P (SP) plays an important role, is closely related to the cross-talk between trigeminal ganglion (TG) neurons and satellite glial cells (SGCs). SGC activation emerging as key mechanism underlying inflammatory pain through different signalling mechanisms, including fibrillary acidic protein (GFAP) activation, phosphorylation of mitogen-activated kinase (MAPK) pathways, cytokine upregulation. However, TG, SP-mediated generated by SGCs...
Abstract Satellite glial cells (SGCs) activation in the trigeminal ganglia (TG) is critical various abnormal orofacial sensation nerve injury and inflammatory conditions. SGCs express several subtypes of P2 purinergic receptors contributing to initiation maintenance neuropathic pain. The P2Y 14 receptor, a G‐protein‐coupled receptor activated by uridine diphosphate (UDP)‐glucose other UDP sugars, mediates physiologic events such as immune, inflammation, However, expression, distribution,...
To investigate how surface treatment affects the color of enamel and dentin, to evaluate whether differences are acceptable.
Introduction Temporomandibular disorders (TMDs) refer to a range of conditions caused by anatomical and functional abnormalities the temporomandibular joints. Anterior disc displacement with reduction (ADDwR) is one most common TMDs, characterized symptoms such as jaw pain audible clicking during movements. Case report A 38-year-old female was admitted our hospital in April 2023 chief complaint joint snapping persisting for nearly decade. After comprehensive examination, she diagnosed ADDwR...
To compare the sagittal condylar inclination (SCI) in dentate individuals measured by different methods with mechanical articulator (MA), virtual (VA), and a jaw tracking device (JTD) system.A total of 22 healthy participants were enrolled this study. For MA workflow, SCI was obtained semi-adjustable protrusive interocclusal records. The also set on VA aligning intraoral scan (IOS) cone beam computed tomography (CBCT) facial (FS), respectively. These workflows conducted dental design...
The cross talk between trigeminal ganglion (TG) neurons and satellite glial cells (SGCs) is crucial for the regulation of inflammatory orofacial pain. Substance P (SP) plays an important role by activating neurokinin (NK)-I receptors in this talk. activation extracellular signal-regulated kinase (ERK) 1/2, protein A (PKA) C (PKC) SGCs peripheral ganglions inflammation associated with hypersensitivity. This study tested hypothesis that SP evoked SP-NK-I receptor positive feedback via...