- Advanced Radiotherapy Techniques
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Melanoma and MAPK Pathways
- Brain Metastases and Treatment
- Medical Imaging Techniques and Applications
- Advances in Oncology and Radiotherapy
- Click Chemistry and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Lymphatic Disorders and Treatments
- Head and Neck Anomalies
- Glioma Diagnosis and Treatment
- Synthesis of Tetrazole Derivatives
- Urologic and reproductive health conditions
- Global Cancer Incidence and Screening
- Surgical Simulation and Training
- Virtual Reality Applications and Impacts
- Advanced MRI Techniques and Applications
- Urinary Bladder and Prostate Research
- Cancer survivorship and care
- Ultrasound and Hyperthermia Applications
- Colorectal Cancer Surgical Treatments
- Statistical Methods in Clinical Trials
- Lymphadenopathy Diagnosis and Analysis
- Lung Cancer Diagnosis and Treatment
Marqués de Valdecilla University Hospital
2013-2024
Instituto de Investigación Marqués de Valdecilla
2021
Hospital Clínica Benidorm
2015
Abstract Background Encorafenib plus binimetinib (EB) is a standard-of-care treatment for advanced BRAFV600-mutant melanoma. We assessed the efficacy and safety of encorafenib in patients with melanoma brain metastasis (BM) explored if radiotherapy improves duration response. Methods E-BRAIN/GEM1802 was prospective, multicenter, single-arm, phase II trial that enrolled BM. Patients received 450 mg once daily 45 BID, those who achieved partial response or stable disease at first tumor...
We analyzed the long-term oncologic outcome for patients with prostate cancer and transurethral resection who were treated using low-dose-rate (LDR) brachytherapy.From January 2001 to December 2005, 57 consecutive clinically localized cancer. No received external beam radiation. All of them underwent LDR brachytherapy. Biochemical failure was defined according "Phoenix consensus". Patients stratified as low intermediate risk based on The Memorial Sloan Kettering group definition.The median...
Purpose The objective of this study was to characterize the Best Medical Canada microMOSFET detectors for their application in vivo dosimetry high‐dose‐rate brachytherapy (HDRBT) with 192 Ir. We also developed a mathematical model correct dependencies under measurement conditions these detectors. Methods analyzed linearity, reproducibility, and interdetector variability studied response dependence on temperature, source‐detector distance, angular orientation receptor respect source....
Schemes with high doses per fraction and small number of fractions are commonly used in high-dose-rate brachytherapy (HDR-BT) for prostate cancer. Our aim was to analyze the differences between published clinical results predictions radiobiological models absorbed dose required a single monotherapy HDR-BT.Published HDR-BT low- intermediate-risk patients cancer were revised. For 13 studies 16 fractionation schedules 1 9 fractions, dose-response relation terms biochemical control probability...
To evaluate the reduction in absorbed dose delivered to neurovascular bundle (NB) patients with localized prostate cancer treated only HDR brachytherapy and NB protection hyaluronic acid (HA) on side of increase distance from radioactive sources.This is first published report medical literature that studies a new approach decrease toxicity improve quality life for radical as monotherapy. Transperineal HA injection into lateral aspect fat was used consistently displace several autonomic...
Mean (%) 0.58 0.15 0.39 SD 0.98 0.08 0.38 Conclusions:The small differences allows us to state that the safety margin is adequate for a safe treatment.However, more precise feedback TPS would be appropriate reduce this of 3 mm.
The advancement of virtual reality (VR) technology can enrich pedagogical approaches and information communication. In the oncology radiotherapy treatment, medical practitioners revealed two main issues: lack training infrastructure patient comprehension treatment process. Virtual simulation assist in solving these complexities by offering an economical embodiment facility. This study aims to improve user interface experience VR applications from previous work conducting a domain expert...
Abstract Objective : To aim of the study is to determine efficacy and safety treatment with low-dose 3D external beam radiotherapy (EBRT) in patients inguinal lymphorrhea. Material methods We retrospectively analyzed a total 53 persistent lymphorrhea after conservative between 2008 2018. All were treated EBRT photons 6 - 18 MeV. The most common schedules 7.5 Gy 5 fractions (90.7%). Results complete closure fistula was achieved 100% (43/43) patients. Three required re-irradiation due...