A5083404022- Endometrial and Cervical Cancer Treatments
- Glioma Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Brain Metastases and Treatment
- Ovarian cancer diagnosis and treatment
- Prostate Cancer Treatment and Research
- Head and Neck Cancer Studies
- Prostate Cancer Diagnosis and Treatment
- Melanoma and MAPK Pathways
- Head and Neck Surgical Oncology
- Advanced Radiotherapy Techniques
- Uterine Myomas and Treatments
- Angiogenesis and VEGF in Cancer
- Advanced MRI Techniques and Applications
- Cancer Diagnosis and Treatment
- Medical Imaging Techniques and Applications
- MRI in cancer diagnosis
- Management of metastatic bone disease
- Tracheal and airway disorders
- Ultrasound Imaging and Elastography
- Salivary Gland Tumors Diagnosis and Treatment
- Lung Cancer Research Studies
- RNA modifications and cancer
- Cancer Treatment and Pharmacology
- S100 Proteins and Annexins
Universitat de Barcelona
2007-2025
Hospital Clínic de Barcelona
2014-2025
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2008-2021
Agència de Gestió d'Ajuts Universitaris i de Recerca
2021
Azienda Ospedaliero Universitaria Maggiore della Carita
2015
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2015
Hospital Universitari de Vic
2011-2014
Abstract Background The aim of the present study was to evaluate sex-disparities in larynx cancer patients treated with CO 2- Transoral Laser Microsurgery (CO 2 -TOLMS). Methods Retrospective analysis 1290 consecutive patients. Oncologic and functional outcomes were evaluated according sex groups. Survival rates compared by propensity-score matching approach multivariable Cox regression analysis. Results Among patients, 122 (9.5%) females. No significant differences observed tumor exposure,...
Head and neck squamous cell carcinoma (HNSCC) is characterized by high rates of mortality treatment-related morbidity, underscoring the urgent need for innovative safe treatment strategies diagnosis practices. Mitochondrial dysfunction a hallmark cancer can lead to accumulation tricarboxylic acid cycle intermediates, such as succinate, which function oncometabolites. In addition its role in development through epigenetic events, succinate an extracellular signal transducer that modulates...
TPS2096 Background: The receptor for advanced glycation end-products (RAGE) and its ligand high mobility group box 1 (HMGB1) promotes cell proliferation, invasion angiogenesis through mitogen-activated protein kinase (MAPK), nuclear factor kappa B (NF-κB), Akt / mTOR signaling pathways contributes to the rise of glioblastoma (GBM) resistance temozolomide (TMZ). Direct inhibition RAGE showed antitumor antiangiogenic activity in cell-based animal preclinical models GBM. Azeliragon, an orally...
Abstract Background Encorafenib plus binimetinib (EB) is a standard-of-care treatment for advanced BRAFV600-mutant melanoma. We assessed the efficacy and safety of encorafenib in patients with melanoma brain metastasis (BM) explored if radiotherapy improves duration response. Methods E-BRAIN/GEM1802 was prospective, multicenter, single-arm, phase II trial that enrolled BM. Patients received 450 mg once daily 45 BID, those who achieved partial response or stable disease at first tumor...
Objective: To evaluate the analgesic efficacy of low-dose radiotherapy in refractory cases trochanteritis. Methods: We evaluated a total 60 consecutive patients who received to achieve an anti-inflammatory and effect for recurrent trochanteritis following scarce response conventional therapy. All were at baseline (prior radiotherapy) 1 4 months after then yearly thereafter pain assessment using visual analogue scale (VAS) determine administration treatment. Results: An improvement...
Abstract Background To evaluate the importance of larynx compartments in prognosis T3‐T4a laryngeal cancer treated with transoral laser microsurgery. Methods Two hundred and two consecutive pT3‐T4a carcinomas. Pre‐epiglottic space involvement, anterior posterior paraglottic (PGS) vocal cord, arytenoid mobility were determined. Local control (LC), overall survival (OS), disease‐specific (DSS), laryngectomy‐free (LFS) evaluated. Results The lowest LC was found tumors fixed arytenoid. In...
Glioblastoma is the most aggressive brain tumor in adults and has few therapeutic options. The study of molecular subtype classifications may lead to improved prognostic classification identification new targets. Cancer Genome Atlas (TCGA) mainly been applied U.S. clinical trials, while intrinsic glioma (IGS) European trials.From paraffin-embedded samples 432 patients with uniformly treated, newly diagnosed glioblastoma, we built tissue microarrays for IHC analysis RNA sequencing best...
Radiation pneumonitis (RP) is a lung disease that appears after thoracic irradiation of different malignancies. Pathophysiology, clinical aspects, outcome, and treatment are reported. Clinical RP related to factors, the most important being irradiated volume radiotherapy dose. appearing in cancer, breast Hodgkin disease, esophageal head neck total body irradiation, also future trends avoid this complication discussed.