A5022669179- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Cervical Cancer and HPV Research
- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- Breast Cancer Treatment Studies
- Sarcoma Diagnosis and Treatment
- HER2/EGFR in Cancer Research
- Colorectal and Anal Carcinomas
- Breast Lesions and Carcinomas
- Cancer Treatment and Pharmacology
- Cancer Diagnosis and Treatment
- Reproductive Biology and Fertility
- Cancer Risks and Factors
- Angiogenesis and VEGF in Cancer
- Urinary and Genital Oncology Studies
- Monoclonal and Polyclonal Antibodies Research
- Genital Health and Disease
- Lung Cancer Research Studies
- Breast Implant and Reconstruction
- Glycosylation and Glycoproteins Research
- Cutaneous Melanoma Detection and Management
- Management of metastatic bone disease
- Head and Neck Cancer Studies
- Renal cell carcinoma treatment
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer
2010-2022
Hospital Clínic de Barcelona
2010-2022
Universitat de Barcelona
2010-2022
Australia New Zealand Gynaecological Oncology Group
2020
Gynecologic Oncology Group
2020
Hospital Universitari de Vic
2002-2016
Hospital de Clínicas
2013
University Hospital and Clinics
2011
Laboratoire de Biochimie
1996
Clínica Rementería
1993
Objective Using highly sensitive polymerase chain reaction ( PCR ) techniques, we reanalysed all cervical carcinomas CC s) found to be human papillomavirus HPV )‐negative by Hybrid Capture 2 HC 2) determine the prevalence of true ‐negativity. We also evaluated characteristics patients with tumours confirmed Design Observational study. Setting Barcelona, Spain. Population A cohort 136 women (32 adenocarcinomas, 104 squamous cell carcinomas) who had pre‐treatment testing. Methods All negative...
BACKGROUND Human epididymis protein 4 (HE4), a precursor of human protein, has been proposed as tumor marker for ovarian cancer. We evaluated HE4 in comparison with cancer antigen 125 (CA 125) healthy individuals and patients benign malignant diseases. METHODS CA serum concentrations were determined 101 individuals, 535 pathologies (292 gynecologic diseases) 423 diseases (127 cancers). cutoffs 35 kU/L 140 pmol/L, respectively. RESULTS results abnormal 1.1% 9.9% 12.3% 37% diseases, Renal...
The aim of this study is to evaluate a new tumour marker, HE4, in comparison with CA 125 and the Risk Ovarian Malignancy Algorithm (ROMA) healthy women patients benign malignant gynaecological diseases. HE4 serum levels were determined 66 women, 285 diseases (68 endometriosis, 56 myomas, 137 ovarian cysts 24 other diseases), 33 non-active cancer 143 active (111 cancers). cut-offs 35 U/mL 150 pmol/L, respectively. ROMA algorithm cut-off was 13.1 27.7 for premenopausal or postmenopausal...
Localization of sentinel lymph nodes can be challenging if they are in difficult anatomic locations or near high radiotracer activity. The purpose this study was to assess the value intraoperative real-time imaging using a portable γ-camera conjunction with conventional γ-counting probe when it is localize node. <b>Methods:</b> After <sup>99m</sup>Tc-nanocolloid injection, patients various malignancies underwent presurgical lymphoscintigraphy followed by surgery (usually next day). We...
Mesonephric (wolffian) neoplasms of the female genital tract are infrequent and found in sites where embryonic remnants wolffian origin usually detected, such as uterine cervix, broad ligament, mesosalpinx, ovary. Their diagnosis is difficult because absence specific immunohistochemical markers for mesonephric derivatives. We present first report adenocarcinoma type arising a purely myometrial mass without endometrial or cervical involvement corpus 33-year-old woman. The tumor showed...
The objective of this study was to determine the value myometrial invasion by magnetic resonance imaging (MRI), histologic typing and grading endometrial biopsy, intraoperative evaluation both parameters frozen section in cancer. preoperative records 180 patients with cancer were used compare MRI, sections, final histopathologic findings. biopsy gave us tumor type grade. MRI depth invasion. sections type, grade, also Patients classified as low risk (grade 1 2, <50%) high 3 or >50%). Standard...
The utility of carcinoembryonic antigen (CEA) and carbohydrate 15.3 (CA 15.3) as prognostic factors in primary breast cancer is unclear.We prospectively studied CEA CA the sera 2062 patients with untreated diagnosed between 1984 2008.Increased (>5 microg/L) (>30 kU/L) concentrations were found 12.7% 19.6% patients, respectively, 1 or both tumor markers increased 28% (570 2062). Increases each marker correlated larger sizes nodal involvement. Tumor size, estrogen receptor (ER), independent by...
Tumor markers were studied in the sera of 883 untreated patients with primary breast cancer diagnosed between 1989 and 2007. Abnormal human epidermal growth factor receptor 2 (HER-2)/neu levels (>15 ng/mL) found 9.5%, carcinoembryonic antigen (CEA) 15.9%, (CA) 15.3 19.7% patients. One or more tumor abnormal 305 (34.5%) Significantly higher serum HER-2/neu tissue overexpression this oncoprotein (p < 0.0001). CEA, CA 15.3, (only those overexpression) related stage (tumor size nodal...
The aim of this study was to evaluate the feasibility, efficacy, and morbidity laparoscopic ovarian transposition on preservation hormonal function in patients younger than 45 years operated for early cervical cancer. According risk factors pathologic evaluation specimen, some them will receive postoperative pelvic radiotherapy. This subset could benefit from taking ovaries away irradiation field an effort preserve their functionality. prospective included 28 FIGO stage IB1 cancer patients,...
To describe and analyze the diagnostic performance of uterine virtual navigation with three-dimensional (3D) ultrasonography (US) for assessment depth myometrial infiltration by endometrial cancer.Institutional review board approval was obtained; patients gave oral informed consent. Women cancer were evaluated using 3D US prior to surgical staging. A volume whole uterus obtained analyzed software. Virtual through three orthogonal planes performed identify shortest tumor-free distance serosa...
The aim of this study was to compare the feasibility, safety, and survival outcomes Coelio-Schauta (CS) procedure versus open Wertheim-Meigs (WM) as primary surgical treatment early-stage cervical cancer.Observational on consecutive cases cancer undergoing CS during last 11 years at our institution performed. Data clinical characteristics patients, performance, long-term morbidity, were prospectively analyzed compared with a historical series 23 WM performed same hospital in immediate...