A5087829608- Neonatal Respiratory Health Research
- Retinopathy of Prematurity Studies
- Congenital Heart Disease Studies
- Neonatal and fetal brain pathology
- Mechanical Circulatory Support Devices
- Cardiovascular Conditions and Treatments
- Infant Nutrition and Health
- Clinical Nutrition and Gastroenterology
- Pediatric Hepatobiliary Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Retinal Diseases and Treatments
- Neonatal Health and Biochemistry
- Congenital Diaphragmatic Hernia Studies
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Sepsis Diagnosis and Treatment
- Assisted Reproductive Technology and Twin Pregnancy
- Preterm Birth and Chorioamnionitis
- Neonatal and Maternal Infections
- Chronic Disease Management Strategies
- Genomic variations and chromosomal abnormalities
- Renal and related cancers
- Cardiac and Coronary Surgery Techniques
- Cardiac Ischemia and Reperfusion
- Ion Transport and Channel Regulation
Albany Medical Center Hospital
2015-2025
University of Pennsylvania
2024
Robert Wood Johnson Foundation
2023
Eaton (United States)
2023
University of Miami
2023
University College London
2019
Thrombosis Research Institute
2019
KLE Society Hospital
2018
Sir Ganga Ram Hospital
2018
Background/Objectives: Pneumothorax is a common complication of neonatal respiratory distress syndrome, which decreased by surfactant therapy. Rescue administration in neonates with severe RDS complicated pneumothorax requires management the to optimize distribution while avoiding positive pressure ventilation minimize iatrogenic exacerbation air leak. Methods: We retrospectively reviewed our center’s experience who had clinically significant complicating RDS, whom we used novel technique...
Background Human milk-derived fortifier (HMDF) coupled with human milk feeding in extremely premature infants reduces the adverse outcome risks of early exposure to bovine ingredients but may not provide enough nutrients for adequate catch-up growth compared (BMDF). Objective This study aims compare HMDF and BMDF effects on parameters serum 25-hydroxy vitamin D (25OHD) levels preterm very low birth weight (VLBW) during first 8 weeks life. Methods We present a retrospective chart review...
Pseudohypoaldosteronism (PHA) is a rare disease that can cause life-threatening hyperkalemia, which could lead to cardiac arrest and death if not recognized treated quickly. We report case of neonate who was diagnosed with PHA type 1 found have novel variant gene mutation on the NR3C2 gene. A 5-day-old newborn presented in severe hyponatremia, metabolic acidosis. Hypothermia treatment initiated due suspected hypoxic-ischemic encephalopathy as well electrolyte management IV fluids bicarbonate...
Patent ductus arteriosus (PDA) is a common finding in preterm infants. Some PDAs will close spontaneously but those that remain open can be associated with significant morbidities and mortality.1-4 The current standard of care to treat hemodynamically PDA (hsPDA) use either intravenous (IV) ibuprofen or IV indomethacin. These medicines have nonselective mechanism COX inhibition which lead side effects.5-7 To avoid this, researchers explored using acetaminophen, has COX-2 selectivity.8, 9...
Continuous improvement in the clinical performance of neonatal intensive care units (NICU) depends on use locally relevant, reliable data. However, databases with these characteristics are typically unavailable NICUs using paper-based records, while those electronic inaccuracy data and inability to customize commercial systems limit their usability for quality or research purposes. We describe uses a simple, neonatologist-centered system that has been successfully maintained 30 years,...
Abstract Aim Few published reports have established B‐type natriuretic peptide ( BNP ) levels in preterm infants without a patent ductus arteriosus PDA ). This study addressed that gap our knowledge by establishing reference range for during the first two weeks of life . Methods We enrolled 36 between 24 and 32 gestation this prospective, noninterventional study. Infants with , congenital heart disease, possible or confirmed sepsis and, or, meningitis, perinatal depression requiring chest...
Abstract The phenotypic variability associated with pathogenic variants in Lysine Acetyltransferase 6B ( KAT6B , a.k.a. MORF MYST4 ) results several interrelated syndromes including Say‐Barber‐Biesecker‐Young‐Simpson Syndrome and Genitopatellar Syndrome. Here we present 20 new cases representing 10 novel variants. These patients exhibit a range of clinical phenotypes intellectual disability, mobility language difficulties, craniofacial dysmorphology, skeletal anomalies. Given the features...
In neonates, blood flow to the brain as measured by peak systolic velocity (PSV) in middle cerebral artery (MCA) is altered pregnancies affected chorioamnionitis.We aim determine whether PSV and other measures of MCA fetus are prior development clinical chorioamnionitis following preterm prelabor rupture membranes (PPROM). This was a prospective observational study. Fifty patients from one institution were recruited after being diagnosed with PPROM between 23 weeks zero days 33 six...
Elevation of serum troponin I has been reported in newborns with hypoxic ischemic encephalopathy (HIE), but it is diagnostic and prognostic utility for newborn under 6 hours not clear. Study the predictive value early levels HIE undergoing therapeutic hypothermia (TH) persistent residual (RE) at discharge.Retrospective chart review admitted diagnosis to neonatal intensive care unit (NICU) TH over a period 3 years. Troponin were drawn initial set admission laboratories while initiating TH....
OBJECTIVE In preterm infants, the standard pharmacologic treatment for a hemodynamically significant patent ductus arteriosus (hsPDA) is either ibuprofen or indomethacin. However, these medications may be less effective after 2 weeks of age. We investigated use acetaminophen in hsPDA closure beyond METHODS An observational study 11 <30 weeks' gestation at birth and postnatal age > weeks, who received their hsPDA. Echocardiograms (ECHOs), B-type natriuretic peptide (BNP) levels,...
We investigated whether a standardized feeding bundle reduces central line utilization in very low birth weight neonates. A chart review of infants ≤1500 g requiring was prepared for 2009 to 2012. Infants were stratified into 3 groups: ≤750 g, 751 1000 and 1001 1500 g. The number line-associated bloodstream infections (CLABSIs) recorded. Central decreased all the 0.45 0.28 infants, 0.4 0.27 0.39 0.3 (all P < 0.001). CLABSIs rate unchanged. Implementation utilization. had no effect on CLABSIs.