A5057700406- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Respiratory Support and Mechanisms
- Neuroscience of respiration and sleep
- Nitric Oxide and Endothelin Effects
- Infant Nutrition and Health
- Neonatal and Maternal Infections
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Preterm Birth and Chorioamnionitis
- Congenital Heart Disease Studies
- Clinical Nutrition and Gastroenterology
- Airway Management and Intubation Techniques
- Neonatal and fetal brain pathology
- Mechanical Circulatory Support Devices
- Infant Development and Preterm Care
- Pediatric Hepatobiliary Diseases and Treatments
- Neonatal Health and Biochemistry
- Palliative Care and End-of-Life Issues
- Pericarditis and Cardiac Tamponade
- Bariatric Surgery and Outcomes
- Electronic Health Records Systems
- Renin-Angiotensin System Studies
- Cardiac Structural Anomalies and Repair
Albany Medical Center Hospital
2014-2024
May Institute
2016
State University of New York
1997
Stony Brook University
1996-1997
University of Alabama at Birmingham
1995
Louisiana State University Health Sciences Center New Orleans
1993-1995
Louisiana State University
1993-1995
University Medical Center New Orleans
1994
All India Institute of Medical Sciences
1992
The influx of inflammatory mediators and cells into the tracheobronchial effluent preterm infants with respiratory distress syndrome (RDS) appears to be important in signaling development bronchopulmonary dysplasia (BPD). mechanism that initiates this early response is not well understood. purpose study was test hypothesis whether increased interleukin-8 (IL-8), a potent chemoattractant for human neutrophils, airways RDS whom BPD develops before neutrophils. In addition, airway secretions...
Background Human milk-derived fortifier (HMDF) coupled with human milk feeding in extremely premature infants reduces the adverse outcome risks of early exposure to bovine ingredients but may not provide enough nutrients for adequate catch-up growth compared (BMDF). Objective This study aims compare HMDF and BMDF effects on parameters serum 25-hydroxy vitamin D (25OHD) levels preterm very low birth weight (VLBW) during first 8 weeks life. Methods We present a retrospective chart review...
Neonatal necrotizing enterocolitis which develops after feeding preterm infants is characterized by severe intestinal inflammation and profound systemic metabolic acidosis. The fermentation of undigested dietary carbohydrate colonic flora yields gases (CO2 H2) short chain organic acids. These acids can disrupt the mucosa initiate driven predominantly resident mast cells granulocytes are recruited from blood. A acidosis ensues derived acids, not classic lactic produced anaerobic metabolism....
Vitamin D supplementation in preterm infants has been recommended by American Academy of Pediatrics (AAP); however, its efficacy and safety not well studied. To study 25-hydroxy vitamin (25OHD) levels as a marker status very low birth weight while on during neonatal intensive care unit hospitalization.Retrospective with <1500 g admitted to our from January 2013 December 2015 who were oral D3 400 IU supplementation. Serum 25OHD level checked at 4, 8, 12 weeks age or before discharge the...
Maternal obesity has been associated with pregnancy-related complications and neonatal morbidities. The primary aim of this study was to evaluate early morbidities maternal from the infant-mother dyad data set at a single, large Regional Perinatal Center (RPC) in NY. A retrospective chart review all mother-infant dyads born January 2009 December 2019 done. defined using NIH definition pre-pregnancy body mass index (BMI) ≥ 30 Kg/m2. included BMI, gestational diabetes, hypertension, mode...
Objectives: To assess neonatologists' practices, knowledge, and opinions regarding the prevention of endobronchial intubation. Design: Anonymous survey. Subjects Setting: Program Directors Neonatology Fellowship Programs in United States, surveyed by mail, neonatologists who volunteered to respond while attending Vermont-Oxford Network Annual Meeting. Interventions: None. Measurements Main Results: directors (response rate 66%) other practitioners contributed equally 132 survey responses,...
Continuous improvement in the clinical performance of neonatal intensive care units (NICU) depends on use locally relevant, reliable data. However, databases with these characteristics are typically unavailable NICUs using paper-based records, while those electronic inaccuracy data and inability to customize commercial systems limit their usability for quality or research purposes. We describe uses a simple, neonatologist-centered system that has been successfully maintained 30 years,...
Abstract Aim Few published reports have established B‐type natriuretic peptide ( BNP ) levels in preterm infants without a patent ductus arteriosus PDA ). This study addressed that gap our knowledge by establishing reference range for during the first two weeks of life . Methods We enrolled 36 between 24 and 32 gestation this prospective, noninterventional study. Infants with , congenital heart disease, possible or confirmed sepsis and, or, meningitis, perinatal depression requiring chest...
Objective More women are obese at their first prenatal visit and then subsequently gain further weight throughout pregnancy than ever before. The impact on the infant’s development of neonatal hypoxic ischemic encephalopathy (HIE) has not been well studied. Using defined physiologic neurologic criteria, our primary aim was to determine if maternal obesity conferred an additional risk HIE. Study Design Data from New York State Perinatal System all singleton, term births in Northeastern region...
Objectives Unplanned extubation (UE) rate is a patient safety metric for which there are varied and inconsistently interpreted definitions. We aimed to test the sensitivity of UE rates application different operational Methods analyzed neonatal intensive care unit (NICU) quality improvement data on events defined inclusively as “any that was not performed electively, or previously intended time.” extubations were classified involving an endotracheal tube (ETT) either objectively “dislodged”...
Elevation of serum troponin I has been reported in newborns with hypoxic ischemic encephalopathy (HIE), but it is diagnostic and prognostic utility for newborn under 6 hours not clear. Study the predictive value early levels HIE undergoing therapeutic hypothermia (TH) persistent residual (RE) at discharge.Retrospective chart review admitted diagnosis to neonatal intensive care unit (NICU) TH over a period 3 years. Troponin were drawn initial set admission laboratories while initiating TH....
The fetus of a 29 year old G2P1 was diagnosed on routine prenatal ultrasound in the early second trimester with gastroschisis. Classically, gastroschisis is right-sided periumbilical abdominal wall defect. Our case highly unusual because defect left. None current theories embryogenesis right sided adequately explain how can arise Associated congenital anomalies are rare but our patient had left talipes deformity, digital hand and persistent superior vena cava. Also, severe problems...
It is unknown how often preterm infants in neonatal intensive care units achieve the American Academy of Pediatrics-recommended daily intake 400 international Vitamin D. We studied 378 with birth weight 1500 g or less admitted to our unit, 151 before and 227 after vitamin D-intake monitoring was introduced. Infants were stratified into 2 groups: extremely low (<1000 g) Very (1000-1500 g). Monitoring coincided significant improvement D both very groups.
Endothelin and nitric oxide are both endothelium-derived vasoactive factors which appear to play a role in variety of circulatory disorders (Leppaluoto Ruskoaho, 1992; Moncada et al., 1991; Nathan, Rubanyi Parker Botelho, 1991). Boulanger Lüscher (1990) noted isolated blood vessels that the release endothelin were inversely related. The intracellular levels cGMP be determinant this response, i.e., elevated decreased release, while promotes release. In contrast inhibition by oxide, Hirata al....
Unintended endobronchial placement is a common complication of neonatal tracheal intubation and threat to patient safety, but it has received little attention towards decreasing its incidence mitigating associated harms. We report on the key aspects long-term project in which we applied principles safety design implement safeguards establish culture, aiming decrease rate deep (beyond T3) neonates <10%. Results from 5745 consecutive intubations revealed 47% tube at baseline, decreased 10-15%...