A5077696367- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Neuroscience of respiration and sleep
- Respiratory Support and Mechanisms
- Infant Development and Preterm Care
- Integrated Circuits and Semiconductor Failure Analysis
- Silicon and Solar Cell Technologies
- Neonatal and Maternal Infections
- Infant Nutrition and Health
- Sepsis Diagnosis and Treatment
- Neonatal and fetal brain pathology
- Neonatal Health and Biochemistry
- Congenital Heart Disease Studies
- Child and Adolescent Health
- Streptococcal Infections and Treatments
- Ion-surface interactions and analysis
- Congenital Anomalies and Fetal Surgery
- Plasma Diagnostics and Applications
- Nitric Oxide and Endothelin Effects
- Airway Management and Intubation Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Breastfeeding Practices and Influences
- Pharmaceutical studies and practices
- Ethics and Legal Issues in Pediatric Healthcare
- Prenatal Substance Exposure Effects
The Christie NHS Foundation Trust
2023-2025
Albany Medical Center Hospital
2015-2024
490 BioTech (United States)
2023
University of California Davis Medical Center
2022
Johns Hopkins University
2022
Eunice Kennedy Shriver National Institute of Child Health and Human Development
2022
American Congress of Obstetricians and Gynecologists
2020
Children's Hospital of Philadelphia
2018
East Carolina University
2004-2016
Varian Medical Systems (United States)
1997-2016
This Policy Statement was reaffirmed December 2021. Provision of risk-appropriate care for newborn infants and mothers first proposed in 1976. updated policy statement provides a review data supporting evidence tiered provision reaffirms the need uniform, nationally applicable definitions consistent standards service public health to improve neonatal outcomes. Facilities that provide hospital should be classified on basis functional capabilities, these facilities organized within...
Maternal use of certain drugs during pregnancy can result in transient neonatal signs consistent with withdrawal or acute toxicity cause sustained a lasting drug effect. In addition, hospitalized infants who are treated opioids benzodiazepines to provide analgesia sedation may be at risk for manifesting withdrawal. This statement updates information about the clinical presentation exposed intrauterine and therapeutic options treatment is expanded include evidence-based approaches management...
With improved obstetrical management and evidence-based use of intrapartum antimicrobial therapy, early-onset neonatal sepsis is becoming less frequent. However, remains one the most common causes morbidity mortality in preterm population. The identification neonates at risk for frequently based on a constellation perinatal factors that are neither sensitive nor specific. Furthermore, diagnostic tests have poor positive predictive accuracy. As result, clinicians often treat well-appearing...
We evaluated the use of dexamethasone in preterm infants to decrease morbidity associated with bronchopulmonary dysplasia a randomized, double-blind, placebo-controlled trial. Thirty-six (birth weight, ≤250 g and gestational age, ≤30 weeks) who were dependent on oxygen mechanical ventilation at two weeks age received 42-day course (n=13), an 18-day (n=12), or saline placebo (n=11). The starting dose was 0.5 mg per kilogram body weight day, it progressively lowered during period...
The prevention of pain in neonates should be the goal all pediatricians and health care professionals who work with neonates, not only because it is ethical but also repeated painful exposures have potential for deleterious consequences. Neonates at greatest risk neurodevelopmental impairment as a result preterm birth (ie, smallest sickest) are those most likely to exposed number stimuli NICU. Although there major gaps knowledge regarding effective way prevent relieve proven safe therapies...
Respiratory failure secondary to surfactant deficiency is a major cause of morbidity and mortality in preterm infants. Surfactant therapy substantially reduces respiratory for this population. Secondary also contributes acute late-preterm term neonates with meconium aspiration syndrome, pneumonia/sepsis, perhaps pulmonary hemorrhage; replacement may be beneficial these This statement summarizes the evidence regarding indications, administration, formulations, outcomes surfactant-replacement...
The Apgar score provides an accepted and convenient method for reporting the status of newborn infant immediately after birth response to resuscitation if needed. alone cannot be considered as evidence of, or a consequence asphyxia; does not predict individual neonatal mortality neurologic outcome; should used that purpose. An assigned during is equivalent spontaneously breathing infant. American Academy Pediatrics College Obstetricians Gynecologists encourage use expanded form accounts...
Apnea of prematurity is one the most common diagnoses in NICU. Despite frequency apnea prematurity, it unknown whether recurrent apnea, bradycardia, and hypoxemia preterm infants are harmful. Research into development respiratory control immature animals has facilitated our understanding pathogenesis treatment prematurity. However, lack consistent definitions, monitoring practices, consensus about clinical significance leads to significant variation practice. The purpose this report review...
Current practice guidelines recommend administration of surfactant at or soon after birth in preterm infants with respiratory distress syndrome. However, recent multicenter randomized controlled trials indicate that early use continuous positive airway pressure subsequent selective extremely results lower rates bronchopulmonary dysplasia/death when compared treatment prophylactic therapy. Continuous started may be considered as an alternative to routine intubation infants.
The use of donor human milk is increasing for high-risk infants, primarily infants born weighing <1500 g or those who have severe intestinal disorders. Pasteurized may be considered in situations which the supply maternal insufficient. pasteurized safe when appropriate measures are used to screen donors and collect, store, pasteurize then distribute it through established banks. nonpasteurized other forms direct, Internet-based, informal sharing does not involve this level safety...
The anticipated birth of an extremely low gestational age (,25 weeks) infant presents many difficult questions, and variations in practice continue to exist.Decisions regarding care periviable infants should ideally be well informed,ethically sound, consistent within medical teams, consonant with the parents' wishes. Each health institution consider having policies procedures for antenatal counseling these situations. Family may aided by use visual materials, which take into consideration...
To study the effects of inflation pressure and tidal volume (VT) on protein permeability in neonatal pulmonary microcirculation, we measured lung vascular pressures, blood flow, lymph flow (QL), concentrations (L) plasma (P) 22 chronically catheterized lambs that received mechanical ventilation at various peak pressures (PIP) VT. Nine were ventilated initially with a PIP 19 +/- 1 cmH2O VT 10 ml/kg for 2-4 h (base line), after which overexpanded their lungs 58 3 48 4 4-8 h. QL increased from...
“Kangaroo mother care” was first described as an alternative method of caring for low birth weight infants in resource-limited countries, where neonatal mortality and infection rates are high because overcrowded nurseries, inadequate staffing, lack equipment. Intermittent skin-to-skin care (SSC), a modified version kangaroo care, is now being offered resource-rich countries to needing intensive including those who require ventilator support or extremely premature. SSC significantly improves...
This Clinical Report was retired March 2022. Herpes simplex virus (HSV) infection of the neonate is uncommon, but genital herpes infections in adults are very common. Thus, although treating an infant with neonatal a relatively rare occurrence, managing infants potentially exposed to HSV at time delivery occurs more frequently. The risk transmitting during determined part by mother’s previous immunity HSV. Women primary who shedding 10 30 times likely transmit their newborn than women...
Nitric oxide, an important signaling molecule with multiple regulatory effects throughout the body, is tool for treatment of full-term and late-preterm infants persistent pulmonary hypertension newborn hypoxemic respiratory failure. Several randomized controlled trials have evaluated its role in management preterm ≤ 34 weeks' gestational age varying results. The purpose this clinical report to summarize existing evidence use inhaled nitric oxide provide guidance regarding population.
The use of supplemental oxygen plays a vital role in the care critically ill preterm infant, but unrestricted can lead to unintended harms, such as chronic lung disease and retinopathy prematurity. An overly restricted may have adverse effects well. Ideally, continuous monitoring tissue cellular delivery would allow clinicians better titrate oxygen, is not currently feasible clinical setting. introduction pulse oximetry has greatly aided clinician by providing relatively easy estimate...
The American Academy of Pediatrics published a clinical report on late-preterm (LPT) infants in 2007 that was largely based summary 2005 workshop convened by the Eunice Kennedy Shriver National Institute Child Health and Human Development, at which change terminology from “near term” to “late preterm” proposed. This paradigm-shifting recommendation had remarkable impact: federal agencies (the Centers for Disease Control Prevention), professional societies College Obstetricians...