A5076484626- Urinary Tract Infections Management
- Maternal and Perinatal Health Interventions
- Preterm Birth and Chorioamnionitis
- Maternal and fetal healthcare
- Pelvic floor disorders treatments
- Neonatal and Maternal Infections
- Pediatric Urology and Nephrology Studies
- Surgical site infection prevention
- Sepsis Diagnosis and Treatment
- Neuroendocrine regulation and behavior
- Streptococcal Infections and Treatments
- COVID-19 Impact on Reproduction
- Global Maternal and Child Health
- Reproductive System and Pregnancy
- Pregnancy-related medical research
- Cardiovascular Issues in Pregnancy
- Pregnancy and Medication Impact
- Cardiac, Anesthesia and Surgical Outcomes
- Neonatal Respiratory Health Research
- Diversity and Career in Medicine
- Urological Disorders and Treatments
- Urinary Bladder and Prostate Research
- Vaccine Coverage and Hesitancy
- Influenza Virus Research Studies
- Trauma and Emergency Care Studies
Wake Forest University
2019-2023
International Federation of Gynaecology and Obstetrics
2023
John Wiley & Sons (United States)
2023
Atrium Health Wake Forest Baptist
2019-2020
Duke University Hospital
2007-2019
Duke Medical Center
2007-2019
Duke University
2005-2019
Society for Maternal-Fetal Medicine
2015-2018
Duke University Health System
2016-2017
Johns Hopkins University
2015
The Apgar score provides an accepted and convenient method for reporting the status of newborn infant immediately after birth response to resuscitation if needed. alone cannot be considered as evidence of, or a consequence asphyxia; does not predict individual neonatal mortality neurologic outcome; should used that purpose. An assigned during is equivalent spontaneously breathing infant. American Academy Pediatrics College Obstetricians Gynecologists encourage use expanded form accounts...
CDC has updated its interim guidance for U.S. health care providers caring infants born to mothers with possible Zika virus infection during pregnancy (1). Laboratory testing is recommended 1) laboratory evidence of and 2) who have abnormal clinical or neuroimaging findings suggestive congenital syndrome a maternal epidemiologic link suggesting transmission, regardless test results. Congenital recently recognized pattern anomalies associated that includes microcephaly, intracranial...
To estimate whether morbidly obese gravid patients were less likely to develop a surgical site infection after receiving higher dose of preoperative prophylactic antibiotics.A retrospective cohort study pregnant women undergoing cesarean delivery was conducted at two tertiary care centers from 2008 2013. Exposure defined as 2 g compared with 3 cefazolin preoperatively. Disease by diagnosis using Centers for Control and Prevention criteria. We estimated sample size 141 in each group 67%...
Background . Maternal GBS colonization is associated with early-onset neonatal sepsis and extensive efforts are directed to preventing this complication. Less known about maternal risks of colonization. We seek provide a modern estimate the incidence impact invasive disease. Methods A single center historical cohort study all births between 2003 2015 was performed. Data collected via electronic health record abstraction using an institutional specific tool. Descriptive statistics were...
Objective Bacterial colonization of the fetal membranes and its role in pathogenesis membrane rupture is poorly understood. Prior retrospective work revealed chorion layer thinning preterm premature (PPROM) subjects. Our objective was to prospectively examine correlate bacterial presence PPROM, preterm, term Study Design Paired samples (membrane distant) were collected from: PPROM = 14, labor (PTL 8), no (PTNL (TL 10), (TNL Sections probed with cytokeratin identify trophoblast using...
Objective The number of women aged 45 and older who become pregnant is increasing. objective this study was to estimate the risk medical obstetric complications among older. Methods Nationwide Inpatient Sample used identify woman during admission for delivery. Deliveries were identified using International Classification Diseases, Ninth Revision (ICD-9-CM) codes. Using ICD-9-CM codes, pre-existing conditions in at time delivery compared years under age 35. Outcomes 35–44 also 35 determine if...
In Brief OBJECTIVE: To estimate whether maternal serum interleukin (IL)-6 or granulocyte colony-stimulating factor (G-CSF) obtained daily are elevated in women with preterm premature rupture of membranes who develop funisitis. METHODS: Daily blood samples were from and analyzed for IL-6 G-CSF by enzyme-linked immunosorbent assay. Funisitis was determined placental examination. Observations stratified based on the presence absence funisitis analyzed. Proportional hazards models used to...
The objective of this study was to identify factors associated with an increased risk post-operative wound infection in women chorioamnionitis who undergo cesarean delivery.We conducted a retrospective cohort clinical underwent delivery at tertiary-care center between June 2010 and May 2013. Demographic data, labor details outcomes were collected. Women without infections compared.Of 213 delivery, 32 (15%) developed infections. more likely have body mass index (BMI) greater than or equal 40...
Desensitization of the oxytocin receptor (OXTR) in setting prolonged exposure may lead to dysfunctional labor, which increases risk for cesarean delivery, and uterine atony, result postpartum hemorrhage. The molecular mechanism OXTR desensitization is through agonist-mediated recruitment multifunctional protein β-arrestin. In addition its desensitizing function, β-arrestins have recently been shown simultaneously activate downstream signaling. We tested whether stimulation promotes...
Abstract Objective Group B Streptococcus (GBS) colonization of the lower urinary tract in pregnancy is associated with severe infections such as chorioamnionitis, endometritis, and pyelonephritis. The objective this study was to compare rates progression pyelonephritis between GBS Escherichia coli (LUTIs), well infectious obstetric morbidity secondary these pathogens. Study Design Retrospective cohort pregnant women LUTIs (asymptomatic bacteria or acute cystitis [AC]) from a single health...
Die flexible Bronchoskopie ist heute eine Standarduntersuchung und wird nicht nur in fast allen Kliniken, sondern auch im niedergelassenen Bereich durchgeführt. Der überwiegende Teil der Patienten wünscht für diese Untersuchung Sedierung. Eine solche bei komplexen interventionellen Eingriffen, unabhängig von dem Wunsch des Patienten, praktisch immer erforderlich. vorliegende Empfehlung zur Anwendung sedierender Maßnahmen flexiblen basiert auf den Ergebnissen zahlreicher klinischer Studien,...
Objective To estimate the incidence of and define risk factors for postpartum infectious complications after vaginal birth cesarean (VBAC) complicated by chorioamnionitis. Study Design A secondary analysis Eunice Kennedy Shriver National Institute Child Health Human Development Maternal-Fetal Medicine Unit Cesarean Registry was performed. The primary outcome a composite infection: endometritis, sepsis, pelvic abscess, urinary tract infection, necrotizing fasciitis, septic thrombophlebitis....
To evaluate cervical ripening with foley balloon combined a fixed vs. incremental low-dose oxytocin infusion.Women presenting for term labor induction were randomized to or standard infusion following placement. The primary outcome was time from placement delivery.Among 116 subjects, there no difference in median delivery among subjects receiving during of (23.7 19.2 hours). There differences between the two groups bulb extrusion, active and second stage incidence uterine tachysystole, fetal...
Objective The objective of this study was to identify risk factors associated with the development septic pelvic thrombophlebitis (SPT). Study Design This is a secondary case–control Eunice Kennedy Shriver National Institute Child Health and Human Development Maternal-Fetal Medicine Unit Network Cesarean Registry. SPT defined as suspected infectious thrombosis veins, often persistent febrile illness in setting antibiotic therapy for endometritis. Women were compared those without using...
Objective This study aims to estimate postcesarean infectious morbidity in women receiving perioperative β-lactam versus non-β-lactam antibiotics. Methods We conducted a retrospective cohort analysis of the Maternal-Fetal Medicine Unit Cesarean Registry. The exposure was antibiotics regimens at cesarean delivery (CD). stratified by labored unlabored CD. primary composite outcome included wound infection, seroma, hematoma, endometritis, readmission due complication, or debridement....