A5039977539- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- Pleural and Pulmonary Diseases
- COVID-19 diagnosis using AI
- COVID-19 and healthcare impacts
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Telemedicine and Telehealth Implementation
- Lung Cancer Diagnosis and Treatment
- Sepsis Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Climate Change and Health Impacts
- Digital Mental Health Interventions
- COVID-19 and Mental Health
- SARS-CoV-2 detection and testing
- Respiratory viral infections research
- Pharmaceutical studies and practices
- Mobile Health and mHealth Applications
- SARS-CoV-2 and COVID-19 Research
- Trauma Management and Diagnosis
- Animal testing and alternatives
- Autoimmune Neurological Disorders and Treatments
- Data-Driven Disease Surveillance
- Obstructive Sleep Apnea Research
- Ophthalmology and Visual Health Research
West Hertfordshire Hospitals NHS Trust
2018-2023
Watford General Hospital
2020-2022
Central London Community Healthcare NHS Trust
2021
Hampshire Hospitals NHS Foundation Trust
2020-2021
University of California, San Francisco
2020-2021
University of Oxford
2020-2021
National Health Service
2020
Cardiff University
2014
Barnet and Chase Farm NHS Hospitals Trust
2014
Derriford Hospital
2007
What you need to know• Management of covid-19 after the first three weeks is currently based on limited evidence • Approximately 10% people experience prolonged illness Many such patients recover spontaneously (if slowly) with holistic support, rest, symptomatic treatment, and gradual increase in activity Home pulse oximetry can be helpful monitoring breathlessness Indications for specialist assessment include clinical concern along respiratory, cardiac, or neurological symptoms that are...
Maternal use of certain drugs during pregnancy can result in transient neonatal signs consistent with withdrawal or acute toxicity cause sustained a lasting drug effect. In addition, hospitalized infants who are treated opioids benzodiazepines to provide analgesia sedation may be at risk for manifesting withdrawal. This statement updates information about the clinical presentation exposed intrauterine and therapeutic options treatment is expanded include evidence-based approaches management...
What you need to know• Pulse oximeters used at home can detect hypoxia associated with acute covid-19 • Home oximetry requires clinical support, such as regular phone contact from a health professional in virtual ward setting More research is needed understand the safety and effectiveness of optimise service models referral pathways Oxygen levels covid-19Low blood oxygen-technically, hypoxaemia but usually referred hypoxia-can be defined measured oxygen saturation below 94% absence (or 88%...
BackgroundPrimary spontaneous pneumothorax occurs in otherwise healthy young patients. Optimal management is not defined and often results prolonged hospitalisation. Data on efficacy of ambulatory options are poor. We aimed to describe the duration hospitalisation safety compared with standard care.MethodsIn this open-label, randomised controlled trial, adults (aged 16–55 years) symptomatic primary were recruited from 24 UK hospitals during a period 3 years. Patients randomly assigned (1:1)...
Background Digital remote patient monitoring can add value to virtual wards; this has become more apparent in the context of COVID-19 pandemic. Health care providers are overwhelmed, resulting clinical teams spread thinly. We aimed assess impact introducing an app-based system (Huma Therapeutics) on a clinician’s workload COVID-19–specific ward. Objective This prospective feasibility study evaluate health economic effects (in terms workload) mobile app telephone-based ward used patients with...
Risk factors of adverse outcomes in COVID-19 are defined but stratification mortality using non-laboratory measured scores, particularly at the time prehospital SARS-CoV-2 testing, is lacking.Multivariate regression with bootstrapping was used to identify independent predictors patients admitted an acute hospital a confirmed diagnosis COVID-19. Predictions were externally validated large random sample ISARIC cohort (N=14 231) and smaller from Aintree (N=290).983 (median age 70, IQR 53-83;...
Identify predictors of clinical deterioration in a virtual hospital (VH) setting for COVID-19.Real-world prospective observational study.VH remote assessment service West Hertfordshire NHS Trust, UK.Patients with suspected COVID-19 illness enrolled directly from the community (postaccident and emergency (A&E) or medical intake assessment) postinpatient admission.Death (re-)admission to inpatient care during VH follow-up 2 weeks post-VH discharge.900 patients diagnosis (455 referred A&E 445...
Secondary spontaneous pneumothorax (SSP) is traditionally managed with an intercostal chest tube attached to underwater seal. We investigated whether use of a one-way flutter valve shortened patients’ length stay (LoS). This open-label randomised controlled trial enrolled patients presenting SSP and either seal (standard care: SC) or ambulatory care (AC) valve. The type used depended on at randomisation the patient already had in place: those without pleural vent (PV) was used; situ , Atrium...
The objective of this study is to report the pilot phase Targeted Prostate Health Check programme that aims identify men in Surrey and Sussex region who have prostate cancer failed be detected during Covid era.
ABSTRACT Objective Identify predictors of adverse outcome in a Virtual Hospital (VH) setting for COVID 19. Design Real-world prospective observational study. Setting hospital remote assessment service West Hertfordshire NHS Trust, UK. Participants Patients with suspected COVID-19 illness enrolled directly from the community (post-accident and emergency (A&E) or medical intake assessment) post-inpatient admission. Main measure Death (re-)admission to inpatient care over 28 days. Results...
Abstract Background Even when resting pulse oximetry is normal in the patient with acute Covid-19, hypoxia can manifest on exertion. We summarise literature performance of different rapid tests for exertional desaturation and draw this evidence base to provide guidance context COVID-19. Main research questions 1. What exercise have been used assess at home or an ambulatory setting Covid-19 what extent they validated?2. other lung conditions, validated applicability these studies Covid-19?...
<b>Introduction:</b> Respiratory infections make up a significant proportion of acute admissions with half attributed to viral pathogens. POCT for respiratory viruses allows rapid diagnosis. This can influence initial treatment decisions, reducing antibiotic-associated morbidity and facilitating early discharge. <b>Aim:</b> To review whether diagnosis a) optimise antibiotic prescribing b) prevent admission in patients presenting acutely infective symptoms. <b>Methods:</b> We have launched...
Desaturation on exercise has been suggested as a predictive feature for deterioration in COVID-19. The objective of this paper was to determine the feasibility and validity 40-steps desaturation test. A prospective observational cohort study undertaken patients assessed hospital prior discharge. One-hundred fifty-two participants were screened between November 2020 February 2021, 64 recruited perform Patients who able test younger less frail. Four readmitted one patient deteriorated within...
<b>Introduction:</b> This winter has seen the worst flu epidemic in 7 years and exacerbated pressure on hospitals. Early diagnosis emergency department (ED) should prevent transmission to other patients hospitals, help avoid bed closures for infection control (IC) purposes, allow rapid treatment be delivered. <b>Aims & Objectives:</b> To determine whether POCT alters following, with possible influenza: 1. Time (rule in/out of influenza) 2. Proportion admitted from outset a appropriate...
ABSTRACT Introduction Risk factors of adverse outcomes in COVID-19 are defined but stratification mortality using non-laboratory measured scores, particularly at the time pre-hospital SARS-CoV-2 testing, is lacking. Methods Multivariate regression with bootstrapping was used to identify independent predictors a derivation cohort patients. Predictions were externally validated large random sample ISARIC (N=14,231) and smaller from Aintree (N=290). Results 983 patients (median age 70, IQR...