A5091885119- Airway Management and Intubation Techniques
- Healthcare Technology and Patient Monitoring
- Cardiac, Anesthesia and Surgical Outcomes
- Electronic Health Records Systems
- Tracheal and airway disorders
- Patient Safety and Medication Errors
- Hemodynamic Monitoring and Therapy
- Congenital Heart Disease Studies
- Anesthesia and Sedative Agents
- Non-Invasive Vital Sign Monitoring
- Mechanical Circulatory Support Devices
- Machine Learning in Healthcare
- Congenital Diaphragmatic Hernia Studies
- Anesthesia and Neurotoxicity Research
- Pediatric Pain Management Techniques
- Anesthesia and Pain Management
- Neonatal Respiratory Health Research
- Artificial Intelligence in Healthcare and Education
- Transplantation: Methods and Outcomes
- Respiratory Support and Mechanisms
- Organ Donation and Transplantation
- Traumatic Brain Injury Research
- COVID-19 and healthcare impacts
- Wireless Body Area Networks
- Healthcare Operations and Scheduling Optimization
Johns Hopkins All Children's Hospital
2017-2024
Johns Hopkins University
2017-2024
Johns Hopkins Medicine
2019-2024
Children's Hospital of Philadelphia
2011-2020
University of Pennsylvania
2009-2019
Society of Surgical Oncology
2019
Philadelphia University
2010-2017
ECRI Institute
2017
Bolan University of Medical and Health Sciences
2016
Medtronic (Switzerland)
2015
The prevention of pain in neonates should be the goal all pediatricians and health care professionals who work with neonates, not only because it is ethical but also repeated painful exposures have potential for deleterious consequences. Neonates at greatest risk neurodevelopmental impairment as a result preterm birth (ie, smallest sickest) are those most likely to exposed number stimuli NICU. Although there major gaps knowledge regarding effective way prevent relieve proven safe therapies...
Codeine has been prescribed to pediatric patients for many decades as both an analgesic and antitussive agent. is a prodrug with little inherent pharmacologic activity must be metabolized in the liver into morphine, which responsible codeine's effects. However, there substantial genetic variability of hepatic enzyme, CYP2D6, and, consequence, individual patient response codeine varies from no effect high sensitivity. Drug surveillance documented occurrence unanticipated respiratory...
Abstract Objective To develop and evaluate an electronic dashboard of hospital-wide health record medication alerts for alert fatigue reduction quality improvement project. Methods We used visual analytics software to the dashboard. collaborated with Clinical Decision Support committee perform three interventions successively deactivating clinically irrelevant drug–drug interaction (DDI) rules. analyzed impact on care providers’ pharmacists’ override rates using interrupted time series...
Abstract The Norwood surgical procedure restores functional systemic circulation in neonatal patients with single ventricle congenital heart defects, but this complex carries a high mortality rate. In study we address the need to provide an accurate patient specific risk prediction for one-year postoperative or cardiac transplantation and prolonged length of hospital stay purpose assisting clinicians patients’ families preoperative decision making process. Currently available models either...
Lonsdale, Hannah MBChB; Gray, Geoffrey M. PhD; Ahumada, Luis Yates, BS; Varughese, Anna MD; Rehman, Mohamed A. MD Author Information
We designed this study to examine the incidence and degree of movement after administration rocuronium in children adolescents measure treatment effect lidocaine for its prevention.One hundred patients (aged 5-18 yr) were randomly assigned two groups. After general anesthesia was induced with 5 mg/kg thiopental sodium manual occlusion venous outflow performed, one group received 0.1 mL/kg 1% IV. A second isotonic chloride solution as a placebo control. Venous held 15 s, released, immediately...
Over the last few decades, field of anesthesia has advanced far beyond its humble beginnings. Today’s anesthetics are better and safer than ever, thanks to innovations in drugs, monitors, equipment, patient safety. 1–4 At same time, we remain limited by our herd approach medicine. Each patients is unique, but health care today based on a one-size-fits-all approach, while grow older more medically complex every year. By 2050, believe that precision medicine will play central role across all...
We designed this study to examine the incidence and degree of movement after administration rocuronium in children adolescents measure treatment effect lidocaine for its prevention.One hundred patients (aged 5-18 yr) were randomly assigned two groups. After general anesthesia was induced with 5 mg/kg thiopental sodium manual occlusion venous outflow performed, one group received 0.1 mL/kg 1% IV. A second isotonic chloride solution as a placebo control. Venous held 15 s, released, immediately...
In Brief BACKGROUND: Bradycardia is a complication associated with inhaled induction of anesthesia halothane in children Down syndrome. Although bradycardia has been reported after anesthetic sevoflurane these children, the incidence unknown. OBJECTIVES: this study we compared and characteristics syndrome to healthy controls. METHODS: We reviewed electronic records 209 268 control patients who had over an 8-year period. Data extracted from medical record included demographics, history...
Anesthesia Information Management Systems (AIMS) display and archive perioperative physiological data patient information. Although currently in limited use, the potential benefits of an AIMS with regard to enhancement safety, clinical effectiveness quality improvement, charge capture professional fee billing, regulatory compliance, anesthesia outcomes research are great. The processes precautions appropriate for selection, installation, implementation complex, however, have been learned at...
Candidate gene studies have revealed limited genetic bases for opioid analgesic response variability. Genome-wide association facilitate impartial queries of common variants, allowing identification novel contributions to drug effect. Illumina (Illumina Inc, San Diego, CA, USA) single nucleotide polymorphism (SNP) arrays were used investigate SNP associations with total morphine requirement as a quantitative trait locus and postoperative pain in retrospective population opioid-naïve children...
Hospitals use antibiograms to guide optimal empiric antibiotic therapy, reduce inappropriate usage, and identify areas requiring intervention by antimicrobial stewardship programs. Creating a hospital antibiogram is time-consuming manual process that typically performed annually.We aimed apply visual analytics software electronic health record (EHR) data build an automated, ("e-antibiogram") adheres national guidelines contains filters for patient characteristics, thereby providing access...
Perioperative pediatric adverse events have been challenging to study within and across institutions due varying definitions, low event rates, incomplete capture.The aim of this was determine perioperative prevalence evaluate associated case characteristics potential contributing factors at an academic quaternary-care center.At the Children's Hospital Philadelphia (CHOP), requiring rapid response assistance are termed Anesthesia Now (AN!) events. They accurately captured entered into a...
The American Academy of Pediatrics proposes guidance for the pediatric perioperative anesthesia environment. Essential components are identified to optimize environment anesthetic care infants and children. Such an promotes safety well-being children by reducing risk adverse events.
BackgroundDifficult facemask ventilation is perilous in children whose tracheas are difficult to intubate. We hypothesised that certain physical characteristics and anaesthetic factors associated with mask paediatric patients who also had tracheal intubation.MethodsWe queried a multicentre registry for experienced "difficult" or "impossible" ventilation. Patient case known before attempt were included consideration this regularised multivariable regression analysis. Incidence of...
BackgroundThe Paediatric Difficult Intubation Collaborative identified multiple attempts and persistence with direct laryngoscopy as risk factors for complications in children difficult tracheal intubations subsequently engaged initiatives to reduce repeated children. We hypothesised these efforts would lead fewer attempts, decrease complications.MethodsPaediatric patients less than 18 years of age were enrolled the Registry. define those whom (1) an attending or consultant obtained a...
<sec> <title>BACKGROUND</title> Recent advancements in sports medicine have been fueled by innovative technologies, particularly consumer-grade wearable devices like Fitbit, Apple Watch, and Garmin. These offer physiological biomechanical data hold promise for personalized, real-time, remote assessment of athlete recovery. However, few studies conducted with these adolescent student athletes. </sec> <title>OBJECTIVE</title> The primary objective this study was to assess the feasibility...