A5103052556- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Sedative Agents
- Congenital Heart Disease Studies
- Veterinary Pharmacology and Anesthesia
- Airway Management and Intubation Techniques
- Hemodynamic Monitoring and Therapy
- Veterinary Equine Medical Research
- Antibiotics Pharmacokinetics and Efficacy
- Cardiac Valve Diseases and Treatments
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Aortic Disease and Treatment Approaches
- Pharmaceutical and Antibiotic Environmental Impacts
- Congenital Diaphragmatic Hernia Studies
- Cardiac electrophysiology and arrhythmias
- Patient Safety and Medication Errors
- Child and Adolescent Health
- Neonatal Respiratory Health Research
- Healthcare and Environmental Waste Management
- Environmental Education and Sustainability
- Down syndrome and intellectual disability research
- Cardiovascular and Diving-Related Complications
- Mechanical Circulatory Support Devices
- Telemedicine and Telehealth Implementation
- Pharmacological Effects and Assays
University of Hertfordshire
2024
University of the West of England
2023
University of Bath
2021-2022
Children's National
2017
Monroe Carell Jr. Children's Hospital
2012-2016
Vanderbilt University
2014-2016
British Columbia Children's Hospital
2014-2015
University of British Columbia
2014-2015
Children's Hospital of Philadelphia
2015
Primary Children's Hospital
2015
Studies in dogs with an emulsion formulation of the intravenous anaesthetic, propofol, showed that induction anaesthesia was smooth and it possible to maintain by intermittent injection. The mean dose for unpremedicated 5.95 mg/kg body-weight. When no premedication administered maintained a total approximately 0.806 mg/kg/minute. Premedication between 0.02 0.04 acepromazine reduced about 30 per cent maintenance more than 50 cent. In 68 given one dose, recovery complete time 18 minutes after...
The goal of this project is to measure the impact standardization transfusion practice on blood product utilization and postoperative bleeding in pediatric cardiac surgery patients.Transfusion common following cardiopulmonary bypass (CPB) children associated with increased mortality, infection, duration mechanical ventilation. Transfusion often based clinical judgment rather than objective data. Although algorithms have demonstrated efficacy for reducing adult surgery, such not been applied...
Summary Objective Children undergoing congenital cardiac surgery ( CCS ) are at increased risk for acute kidney injury AKI due to a number of factors. Recent evidence suggests may influence mortality beyond the immediate postoperative period and hospitalization. We sought determine association between renal failure longer‐term in children following . Methods Our Study population included all patients that underwent our institution during 3 years from 2004 through 2006. The primary definition...
Down-the-drain disposal of pharmaceuticals remains an overlooked and unrecognized source environmental contamination that requires nontechnological "at-source" solutions. Monitoring 31 over 7 days in five wastewater treatment plants (WWTPs) serving cities South-West UK revealed down-the-drain codisposal six to three WWTPs (carbamazepine propranolol city A, sildenafil B, diltiazem, capecitabine, sertraline D), with a one-off record estimated 253 pills = 40 g carbamazepine 96 4 A accounting...
BackgroundDifficult facemask ventilation is perilous in children whose tracheas are difficult to intubate. We hypothesised that certain physical characteristics and anaesthetic factors associated with mask paediatric patients who also had tracheal intubation.MethodsWe queried a multicentre registry for experienced "difficult" or "impossible" ventilation. Patient case known before attempt were included consideration this regularised multivariable regression analysis. Incidence of...
Abstract Pharmaceuticals can enter the environment through disposal in toilets, sinks and general waste. In UK, household medicines are correctly disposed of by returning them to a pharmacy. This study examined patterns medicine waste, storage practices via cross-sectional survey with 663 UK adults. Multiple regression was used explore contribution key variables on self-reported behaviour. Analysis demonstrated that age, information, awareness, probability, attitude intention all predicted...
Survival from in-hospital cardiac arrest is approximately 18%, but for patients who require advanced airway management survival lower. Those do survive are often left with significant disability. Traditionally, resuscitation of has included tracheal intubation, however insertion a supraglottic gained popularity as an alternative approach to management. Evidence out-of-hospital suggests no differences in mortality or morbidity between these two approaches, there randomised evidence during...
Patients with long QT syndrome (LQTS) may experience a clinical spectrum of symptoms, ranging from asymptomatic, through presyncope, syncope, and aborted cardiac arrest, to sudden death. Arrhythmias in LQTS are often precipitated by autonomic changes. This patient population is believed be at high risk for perioperative arrhythmia, specifically torsades de pointes (TdP), although this perception largely based on limited literature that predates current anesthetic drugs standards monitoring....
Abstract Aim To explore the usefulness of a co‐designed wordless book showing processes receiving COVID‐19 vaccines designed by, and for, adults with intellectual disabilities. Methods A qualitative evaluation resource using mixed methods. Semi‐structured interviews were conducted people disabilities, carers health professionals about content, use. This was analysed thematically. survey circulated to disabilities networks understand need, use, sharing content. Results Understanding vaccine...
After premedication with intravenous xylazine 30 ponies were anaesthetised for castration under field conditions ketamine, thiopentone or methohexitone. The duration of anaesthesia was adequate surgery and the times taken to stand similar in each group. recovery after ketamine quieter than either barbiturates this may be an advantage when skilled assistance is lacking. However, all anaesthetics appeared suitable performing minor field.
The pressure flow characteristics of a demand valve which has been suggested to be suitable for use in anaesthetised horses were determined at range rates commonly encountered equine anaesthesia. resistance the was found very much greater than normal large animal anaesthetic apparatus or lower respiratory tract. effects on pulmonary ventilation investigated seven anaesthetised, intubated horses. Respiratory rate and dynamic compliance unaffected by connection but mean tidal minute volumes...
Gas emboli, including venous and arterial, are a rare but important complication of pediatric cardiac surgery. They have the potential to devastating consequences require prompt recognition treatment. We present case gas embolism occurring in immediate postoperative period an infant with cyanotic congenital heart disease after palliative surgery resulting cardiopulmonary arrest. The was diagnosed by visualization air within vessel creating airlock occluding pulmonary blood flow.
Whyte, Simon D.*; Nathan, Aruna†; Myers, Dorothy*; Watkins, Scott C.‡; Kannankeril, Prince J.§; Etheridge, Susan P.∥; Andrade, Jason¶; Collins, Kathryn K.#; Law, Ian H.**; Hayes, Jason††; Sanatani, Shubhayan‡‡ Author Information
General practitioners (GPs) face complex decisions when choosing between prescribing medication or referring patients to social prescriptions. Increasing awareness of overprescribing and the risks polypharmacy are a key driver patient‐centred preventative approaches healthcare. One such approach, increasingly common in United Kingdom, is (SP). GPs have central role prescription. Following thematic analysis data from interviews with 12 GPs, this study used concept mindlines frame...