A5017869122- Airway Management and Intubation Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Patient Safety and Medication Errors
- Anesthesia and Sedative Agents
- Cardiac Arrest and Resuscitation
- Tracheal and airway disorders
- Asthma and respiratory diseases
- Healthcare Systems and Reforms
- Global Maternal and Child Health
- Foreign Body Medical Cases
- Child Nutrition and Water Access
- Healthcare Technology and Patient Monitoring
- Obstructive Sleep Apnea Research
- Pediatric health and respiratory diseases
- Atherosclerosis and Cardiovascular Diseases
- Neuroscience of respiration and sleep
- Vascular Malformations Diagnosis and Treatment
- Connective tissue disorders research
- Takotsubo Cardiomyopathy and Associated Phenomena
- HIV/AIDS Impact and Responses
- Long-Term Effects of COVID-19
- Neuroscience and Neuropharmacology Research
- COVID-19 and healthcare impacts
- Cerebral Venous Sinus Thrombosis
- Vector-borne infectious diseases
George Washington University
2013-2025
Children's National
2013-2023
George Washington University Hospital
2022
Seattle Children's Hospital
2014-2015
University of Washington
2015
Cincinnati Children's Hospital Medical Center
2015
University of Cincinnati Medical Center
2015
Johns Hopkins University
2013-2015
Children's Hospital of Philadelphia
2015
Children's Hospital of Los Angeles
2015
Flexible bronchoscopy is the gold standard for difficult airway management. Clinicians are using videolaryngoscopy increasingly because it perceived to be easier use with high success rates. We conducted this study compare rates of two techniques when used after failed direct laryngoscopy in children tracheal intubations. identified cases where initial attempts at multicentre Pediatric Difficult Intubation Registry from August 2012-September 2023. After propensity score matching, we compared...
Activation of cannabinoid receptors decreases emesis, inflammation, gastric acid secretion, and intestinal motility. However, the effects cannabinoids on permeability have not yet been established. The aim present study is to examine in an vitro model. Caco-2 cells were grown until fully confluent inserts 12-well plates. Transepithelial electrical resistance (TEER) measurements made as a measure permeability. EDTA (50 μM) was applied reversibly increase (reduce TEER). combination with EDTA,...
Inflammation is a key component of arterial injury, with VSMC proliferation and neointimal formation serving as the final outcomes this process. However, acute events transpiring immediately after injury that establish blueprint for inflammatory program are largely unknown. We therefore studied these in mice found following medial VSMCs upregulated Rantes an manner dependent on Stat3 NF-κB (p65 subunit). This led to early T cell macrophage recruitment, processes also under regulation...
Pediatric perioperative cardiac arrest (CA) is a rare but catastrophic event. This case-control study aims to analyze the causes, incidence, and outcomes of all pediatric CA reported Wake Up Safe. Factors associated with mortality after are examined possible strategies for improving considered.CA in children was identified from Safe Anesthesia Quality Improvement Initiative, multicenter registry adverse events anesthesia. Incidence, demographics, underlying conditions, causes CA, were...
BackgroundThe Paediatric Difficult Intubation Collaborative identified multiple attempts and persistence with direct laryngoscopy as risk factors for complications in children difficult tracheal intubations subsequently engaged initiatives to reduce repeated children. We hypothesised these efforts would lead fewer attempts, decrease complications.MethodsPaediatric patients less than 18 years of age were enrolled the Registry. define those whom (1) an attending or consultant obtained a...
Abstract Background Wake Up Safe, a Patient Safety Organization founded by the Society for Pediatric Anesthesia, collects data on serious adverse events along with demographic from all pediatric patients receiving anesthesia care at participating institutions. This report reviews occurring between 2010 and 2015 focuses common that are anesthesia‐related. Aims Determine which were most to among Safe how many anesthesia‐related deemed be preventable. Methods is descriptive report. The registry...
Application of group I metabotropic glutamate receptor (mGluR) agonists elicits seizure discharges in vivo and prolonged ictal-like activity vitro brain slices. In this study we examined 1) if mGluRs are activated by synaptically released during epileptiform induced convulsants hippocampal slices and, so, 2) whether the contribute to pattern discharges. The GABA(A) antagonist bicuculline (50 microM) was applied induce short synchronized bursts approximately 250 ms mouse Addition...
Epidemiological and clinical characteristics of 210 cases Lyme disease in Westchester County, New York, reported during 1982 1983 are described. Most occurred summer months individuals under age 40 (male: female ratio 1:2 to 1). Symptoms included skin rash (75 per cent), joint pain or swelling (50 Bell's palsy (11 aseptic meningitis (3 cent). With greater public medical awareness this tick-borne disease, is being recognized with increasing frequency characteristic an emerging epidemic County.
Asthma prevalence is lower in less developed countries and among some recent immigrant populations the US, but reasons for this are not clear. One possibility that early childhood infections protective against asthma. We surveyed Asian children (n = 204; age 4–18) to assess relationship between asthma native or foreign place of birth. included questions about environmental exposures, demographic variables family history test whether they might explain effects birth on The born groups were...
Tjia, Imelda*; Rampersad, Sally†‡; Arughese, Anna V.§∥; Heitmiller, Eugenie¶; Tyler, Donald C.#; Lee, Angela C.**; Hastings, Laura A.††; Uejima, Tetsu‡‡ Author Information
Children with SARS-CoV-2 infection are at increased risk for postanesthesia complications. There is minimal data regarding how long that elevated complication persists beyond initial diagnosis.We investigated complications in children within 90 days of completed a single-center, retrospective, case-control study pediatric patients confirmed undergoing anesthesia between January 3-October 7, 2020. Each positive patient was matched 1:2 by age and type procedure non-SARS-CoV-2 cohort. The...
Abstract Background Asthma prevalence among Chinese immigrant children is poorly understood and attempts to screen these have produced varied outcomes. We sought learn how improve screening for asthma in children. Methods Children (n = 152) were administered the Brief Pediatric Screen either Cantonese or English, they then viewed reacted a video showing people wheezing subsequently took pulmonary function test. Results The diagnosed our study population was 27.0%, with another 5.3% having...
Genetic mutations in the fibroblast growth factor receptor 3 gene may lead to achondroplasia or syndromic forms of craniosynostosis. Despite sharing a common genetic basis, craniosynostosis has rarely been described cases confirmed achondroplasia. We report an infant with who developed progressive multiple-suture discuss link between these clinical entities and describe technical challenges associated operative management.
Abstract Background Awareness under general anesthesia occurs rarely, but can result in emotional trauma. Although well‐studied adults, there is a paucity of data on unintentional awareness children. Aims This case series examines instances self‐reported registered with Wake Up Safe, patient safety organization that maintains database adverse events pediatric anesthesia. Methods Cases intraoperative submitted to Safe from January 1, 2010 May 31, 2020 were reviewed for circumstances,...
Abstract Background Transfusion‐associated hyperkalemia (TAH) is a potentially life‐threatening complication of red blood cell (RBC) transfusion. Previously, we reported features RBC transfusions from 35 pediatric patients (TAH group) who had with transfusion in one‐year period at four facilities. In this study, used multivariate analyses and artificial intelligence to compare the TAH group newly collected control (non‐TAH identify factors associated occurrence. Study Design A review was...
Education| September 2023 Every Little Bit Counts: Syringe Dead Space Angela C. Lee, M.D.; M.D. 1Children’s National Medical Center, George Washington University School of Medicine and Health Sciences, Washington, D.C. https://orcid.org/0000-0003-3417-1310 Search for other works by this author on: This Site PubMed Google Scholar Chaitanya Challa, 2Children’s Author Article Information Published online first on July 13, 2023. Address correspondence to Dr. Lee:alee@childrensnational.org...
Hecht–Beals syndrome (HBS) is a rare disorder characterized by trismus and deformity of the extremities. The etiology unknown; theories suggest invasion enlarged coronoid processes into zygomatic bone. Of primary concern limited mouth opening possible difficult airway. Since was first described in 1969, there have been several articles pediatrics dental literature but only 6 case reports describing anesthetic management these patients. Successful airway approaches utilized various techniques...
We present a case of an infant who developed intracranial hypertension after Doxycycline sclerotherapy large right axillary macrocystic lymphatic malformation secondary to significant absorption the drug. This highlights association between and hypertension, even when it is used as sclerosing agent. Clinicians performing taking care infants post need be aware this potential so any signs can identified treated accordingly.
We present a case of severe neurogenic pulmonary edema and arrhythmia complicating management 7-year-old child with acute epidural hematoma impending cerebral herniation. The underlying mechanisms for this are discussed as well edema. emphasize the need to recognize rare complication early institute prompt aggressive management.