- Trace Elements in Health
- Enzyme Catalysis and Immobilization
- Nitric Oxide and Endothelin Effects
- Carbohydrate Chemistry and Synthesis
- Plant Toxicity and Pharmacological Properties
- Alkaloids: synthesis and pharmacology
- Enzyme Production and Characterization
- Glycosylation and Glycoproteins Research
- Pineapple and bromelain studies
- Animal Nutrition and Physiology
- Biofuel production and bioconversion
- Vitamin C and Antioxidants Research
- Iron Metabolism and Disorders
- Educational Research and Science Teaching
- Traditional and Medicinal Uses of Annonaceae
- Pharmacological Effects of Natural Compounds
- Neuropeptides and Animal Physiology
- Antioxidant Activity and Oxidative Stress
- Hydrogen's biological and therapeutic effects
- Moringa oleifera research and applications
- Tea Polyphenols and Effects
- Inflammatory mediators and NSAID effects
- Biochemical Analysis and Sensing Techniques
- Heavy Metal Exposure and Toxicity
- Educational methodologies and cognitive development
Whatcom Community College
2025
Universidad Nacional
2015-2022
Colegio de Postgraduados
2002-2020
Universidad Nacional Agraria de la Selva
2002-2016
Albany College of Pharmacy and Health Sciences
2016
Universidad Complutense de Madrid
2011-2015
Universidad Hispanoamerica
2013
Albany Medical Center Hospital
1999-2005
Chiba University
2003-2005
University of Connecticut
2002
Abstract Biorefineries are a model for greener production processes, based on the concept of bioeconomy. Instead targeting first-generation biofuels—that compete with food supply—the focus relies lignocellulosic material, considering many aspects, such as sustainable fuel production, well valorization waste, an alternative to traditional petrochemical approach goods production. Especially, in tropical countries agricultural activities lead tremendous amounts biomass, resulting waste that has...
Three experiments were conducted to investigate the relative bioavailability of reagent-grade (RG) and feed grade (FG) Zn sources for 1-d-old broiler chicks. In Exp. 1, 13 treatments included a basal corn-soybean meal diet (63 ppm Zn) or supplemented with 400, 800, 1,200 from RG sulfate, basic carbonate, oxide, metal fed 20 d. Using multiple regression slope ratios sulfate set at 100%, estimates 78, 77, 46% metal, respectively. 2, chicks allotted randomly 16 that (75 300, 600, 900 as either...
Genistein, a principal soy isoflavone, has been identified as protein kinase inhibitor that possesses immunosuppressive and anti-inflammatory properties. The aim of the study was to determine if genistein modified chronic ileitis in guinea pigs induced by hapten trinitrobenzene sulfonic acid (TNBS), activity index cultured macrophages (RAW 264.7 cells) stimulated with lipopolysaccharide (LPS). Genistein at low doses (0.1 mg/kg, s.c.) had mild effects TNBS ileitis. Therapeutic benefit...
Four experiments were conducted to identify several factors that might improve the accuracy and reproducibility of Zn bioavailability assays for chicks. Response tissue metallothionein (MT) concentrations various elevated levels soluble sources dietary measured, as well effect delaying high administration until 7 d posthatching alleviate detrimental sulfate on feed intake 3 wk age. Bone increased (P < 0.01) in all response increasing concentrations. Liver pancreas MT affected by a source age...
Sangre de grado is an Amazonian herbal medicine used to facilitate the healing of gastric ulcers and treat gastritis, diarrhea, skin lesions, insect stings. This study was designed evaluate gastrointestinal applications. Gastric were induced in rats by brief serosal exposure fundus acetic acid (80%). administered drinking water at 1:1,000 1:10,000 dilutions from postoperative period day 7. Guinea pig ileum secretory responses capsaicin, electrical field stimulation, neurokinin-1 (NK-1)...
The potential of ascorbic acid and two botanical decoctions, green tea cat's claw, to limit cell death in response oxidants were evaluated vitro. Cultured human gastric epithelial cells (AGS) or murine small intestinal (IEC-18) exposed – DPPH (3 μM), H2O2 (50 peroxynitrite (300 μM) followed by incubation for 24 hours, with antioxidants (10 μg/ml) administered as a 1 hour pretreatment. Cell number (MTT assay) via apoptosis necrosis (ELISA, LDH release) was determined. direct interactions...
Background The purpose of this study was to evaluate the possibility that inducible nitric oxide synthase (iNOS) regulates fetal circulation. Methods and Results Positive evidence for iNOS gene expression noted in heart central vessels placenta untreated rat fetuses. Rats last week pregnancy were treated 5 days with l - N G -(1-Iminoethyl)lysine (L-NIL), a selective inhibitor iNOS, at 1, 10, 100 μg/mL drinking water. To raise NO levels, lipopolysaccharide (LPS) 30 μg/kg given by...
Room temperature ionic liquids (ILs) can affect enzyme activity in some enzyme-catalyzed reactions, however the effects of these cosolvents on enzymes are not clearly understood. Using β-galactosidase from Thermus thermophilus HB27 (TTP0042), we found an important change classical regioselectivity transglycosylation reaction with this enzyme. The increases N-acetyl-D-lactosamine synthesis (Galβ[1→4]GlcNAc) when RTILs used instead traditional self-condensated products. To understand possible...
The use of biocatalysis for the provision optically active building blocks and other useful compounds fine chemicals pharmaceutical industries is nowadays a mature technology. To further improve ecological footprints these applications, there currently an increasing interest in using biomass-derived solvents enzyme-catalyzed processes that may be implemented at industrial level on midterm basis. rationale behind concepts would final replacement petroleum-based by more benign,...
Abstract Tropical crops are an important source of wealth in many countries. The current agribusiness model is based on the production a final commodity, leading to organic by-products (biowastes) that cases contain bioactive compounds with potential added value. exploitation these foundation circular economy leads generation greener bioprocesses for industry foreseeable economic improvements systems. This review aims point out idle opportunities agricultural systems and their associated...
Green solvents made from glycerol change the classical regioselectivity of Biolacta No 5 β-galactosidase, β(1→4) to β(1→6) linkages when a 2 M concentration was used. In order explain these results, non-proteic compounds present in preparation were separated by precipitation with ammonium sulfate and remaining protein extract used set reactions appropriate organic find that towards isomer is retained. According proteomic analysis, 98% homology between Streptococcus pneumoniae β-galactosidase...