A5101633146- Plant biochemistry and biosynthesis
- Biochemical and biochemical processes
- Microbial Metabolic Engineering and Bioproduction
- Biofuel production and bioconversion
- Microbial Natural Products and Biosynthesis
- Bioeconomy and Sustainability Development
- Traditional and Medicinal Uses of Annonaceae
- Food Chemistry and Fat Analysis
- Medicinal Plants and Neuroprotection
- Phytochemistry and Biological Activities
- Algal biology and biofuel production
- Alkaloids: synthesis and pharmacology
- Genetic and Environmental Crop Studies
- Genetic diversity and population structure
- Medicinal Plant Extracts Effects
- Coffee research and impacts
- Chemical synthesis and alkaloids
- Occupational Health and Safety in Workplaces
- Enzyme Catalysis and Immobilization
- Pineapple and bromelain studies
- Chemistry and Chemical Engineering
Leibniz University Hannover
2019-2022
Universidad Autónoma Metropolitana
2014
Abstract Biorefineries are a model for greener production processes, based on the concept of bioeconomy. Instead targeting first-generation biofuels—that compete with food supply—the focus relies lignocellulosic material, considering many aspects, such as sustainable fuel production, well valorization waste, an alternative to traditional petrochemical approach goods production. Especially, in tropical countries agricultural activities lead tremendous amounts biomass, resulting waste that has...
Abstract Tropical crops are an important source of wealth in many countries. The current agribusiness model is based on the production a final commodity, leading to organic by-products (biowastes) that cases contain bioactive compounds with potential added value. exploitation these foundation circular economy leads generation greener bioprocesses for industry foreseeable economic improvements systems. This review aims point out idle opportunities agricultural systems and their associated...
Patchouli oil is a major ingredient in perfumery, granting dark-woody scent due to its main constituent (−)-patchoulol. The growing demand for patchouli has raised interest the development of biotechnological process assure reliable supply. Herein, we report production sesquiterpenes by metabolically engineered Escherichia coli strains, using solid–liquid phase partitioning cultivation. (−)-patchoulol was possible endogenous methylerythritol phosphate pathway and overexpressing synthase...
The sesquiterpene (+)-zizaene is the direct precursor of khusimol, main fragrant compound vetiver essential oil from Chrysopogon zizanioides and used in nearly 20% men's fine perfumery. biotechnological production such sesquiterpenes a promising alternative towards sustainability; nevertheless, product recovery fermentation one constraints. In an effort to improve metabolically-engineered Escherichia coli, we developed integrated bioprocess by coupling using adsorber extractants. Initially,...
The genetic diversity from species of the genus Jatropha collected Costa Rica was analyzed by AFLP (amplified fragments length polymorphism). study consisted 114 accessions 15 populations 4 different species: J. curcas, costaricensis, gossypifolia and stevensii. These were locations in Rica. Three primers used, resulting 428 loci, they classified three categories: unique double bands (UBD), rare (RB) shared (SB). UBD excluded for a total 339 polymorphic loci used UPGMA dendrogram principal...
The aim of this study was to obtain pharmacokinetic data for the anxiolytic compound galphimine-A (G–A) from Galphimia glauca. G–A is most abundant in plant, while Galphimine-E (G–E) galphimine, but inactive. G–E transformed chemically into G–A. carried out ICR mice, which were orally administered a single 200 mg/kg dose Samples blood and brain taken at different times after administration Previously, we established validation methods determining concentration detected plasma 5 min oral...
The vetiver essential oil from Chrysopogon zizanioides contains fragrant sesquiterpenes used widely in the formulation of nearly 20% men’s cosmetics. growing demand and issues supply have raised interest microbial production sesquiterpene khusimol, main compound due to its woody smell. In this study, we engineered biosynthetic pathway for (+)-zizaene, immediate precursor khusimol. A systematic approach metabolic engineering Escherichia coli was applied modulate critical bottlenecks flux...
Zizaene synthase (ZS) from Chrysopogon zizanioides (Poaceae) is the critical enzyme in biosynthesis of fragrant sesquiterpene khusimol, a major component vetiver essential oil used widely by cosmetic industry. As reported previously, we heterologously and successfully expressed active ZS with small ubiquitin-related modifier (SUMO) fusion domain. In this study, report optimization reaction conditions determination kinetics ZS. Moreover, investigate catalytic specificity mechanisms ubiquitous...