A5057726867- Attention Deficit Hyperactivity Disorder
- Autism Spectrum Disorder Research
- Family and Disability Support Research
- Functional Brain Connectivity Studies
- Child Development and Digital Technology
- Child Nutrition and Feeding Issues
- Advanced Neuroimaging Techniques and Applications
- Neural and Behavioral Psychology Studies
- Sleep and related disorders
- Nutrition, Health and Food Behavior
- Infant Development and Preterm Care
- Virology and Viral Diseases
- Food Quality and Safety Studies
- Bipolar Disorder and Treatment
- Ethics and Legal Issues in Pediatric Healthcare
- Pharmaceutical studies and practices
- Health and Well-being Studies
- Cannabis and Cannabinoid Research
- Sleep and Wakefulness Research
- Olfactory and Sensory Function Studies
- Sleep and Work-Related Fatigue
- Mental Health via Writing
- Genetics and Neurodevelopmental Disorders
- Restless Legs Syndrome Research
- Alcohol Consumption and Health Effects
Seoul National University Hospital
2010-2016
Pusan National University Yangsan Hospital
2012-2014
Seoul National University Bundang Hospital
2013
Pusan National University
2013
Increased dopamine availability may be associated with impaired structural maturation of brain white matter connectivity.This study aimed to derive a comprehensive, whole-brain characterization large-scale axonal connectivity differences in attention-deficit/hyperactivity disorder (ADHD) catechol-O-methyltransferase gene (COMT) Val158Met polymorphism.Using diffusion tensor imaging, tractography, and an imaging connectomics approach, we characterized altered youth ADHD who were COMT...
Noradrenergic dysfunction may be associated with cognitive impairments in attention-deficit/hyperactivity disorder (ADHD), including increased response time variability, which has been proposed as a leading endophenotype for ADHD. The aim of this study was to examine the relationship between polymorphisms α-2A-adrenergic receptor (ADRA2A) and norepinephrine transporter (SLC6A2) genes attentional performance ADHD children before after pharmacological treatment.One hundred one medication-naive...
Communication problems are a prevalent symptom of autism spectrum disorders (ASDs), which have genetic background. Although several genome-wide studies on ASD suggested number candidate genes, few reported the association or linkage specific endophenotypes to ASDs.Forty-two Korean patients who showed language delay were enrolled in this study with their parents. We performed scan by using Affymetrix SNP Array 5.0 platform identify genes responsible for ASDs.We detected single-nucleotide...
Dysregulation of noradrenergic system may play important roles in pathophysiology attention-deficit/hyperactivity disorder (ADHD). We examined the relationship between polymorphisms norepinephrine transporter SLC6A2 gene and attentional performance before after medication children with ADHD.Fifty-three medication-naïve ADHD were genotyped evaluated using continuous test (CPT). After 8-weeks methylphenidate treatment, these by CPT again. compared baseline measures post-treatment changes based...
The authors examined the association between MspI C/G and DraI C/T genotypes of α2A-adrenergic receptor gene white-matter connectivity attentional performance before after medication in 53 children with attention-deficit hyperactivity disorder. Subjects who carried T allele at polymorphism showed fewer changes mean commission error scores 8 weeks decreased fractional anisotropy (FA) values right middle frontal cortex than subjects without allele. C FA postcentral gyrus without.
Autism Spectrum Disorder (ASD) is characterized by persistent deficits in social communication and restricted, repetitive patterns of behavior interest. Sleep problems are not uncommon children with autism spectrum disorders. Symptoms insomnia the most frequent sleep individuals ASD. can cause significant difficulties daily life ASD their families. Genetic factor, deregulations melatonin synthesis, extraneous environmental stimuli psychiatric medical conditions may problems. The first line...
Difference of the Naltrexone's Effects in Social Drinkers by Spicy Food PreferenceThe purpose this study was to investigate differences subjective acute effects alcohol and naltrexone among those who prefer spicy food varying degrees.Acute biphasic scale (BAES), visual analogue for craving (VAS-C), blood concentration (BAC) preference were measured 26 men.Repeated measures ANOVA (2 groups × 4 time blocks) on stimulative subscale BAES revealed a significant group block interaction condition...
목 적 : 의학전문대학원 학생들은 과도한 학업으로 인해 수면 시간이 부족하고 수면의 질이 낮다고 알려져 있다. 본 연구는 학생의 양상 및 이와 연관이 있을 것으로 생각되는 심리적 문제를 조사하였다. 방 법 부산대학교 1~4학년 학생 352명을 대상으로 양상, Pittsburgh sleep quality index(PSQI), Epworth sleepiness scale(ESS), global assessment of recent stress scale(GASS), the center for epidemiologic studies-depression scale(CES-D), and Moudsley obsessive-compulsive inventory(MOCI)를 두 군간 연속변수 비교에는 독립 t-검정, 비연속비교는 <TEX>${\chi}^2$</TEX>-검정, 변수간의 상관관계는 Pearson 상관분석, 그리고 세 군 이상 ANOVA를 이용하였다(p<0.05, 양측검정)....
Autism spectrum disorder (ASD) is a neurodevelopmental marked by impaired social communication and repetitive, restricted behaviors activities. The prevalence of ASD has been increasing for the past 2 decades, but evidence-based therapeutic approaches are lacking patients with ASD. To date, there no cure core symptoms ASD, existing treatments focus on improving patient's function adaptation using behavioral intervention methods. Behavioral interventions have proven to show greatest effect...
Pbjective : A significant proportion of children with autism spectrum disorders (ASD) have regression characterized by loss previously acquired skills. The purpose this study was to compare demographic, clinical characteristics and autism-related symptomatology the who don't regression. Methods subjects ASD their unaffected siblings (SIB) were recruited from Korean Autism Genetic Study Consortium. Typically developing (TC) volunteered community. administered version Diagnostic...
Objectives : Dysregulation of the central noradrenergic system may be involved in pathophysiology attention-deficit hyperactivity disorder (ADHD). The aim this study was to examine differences pre- and post-treatment cerebral perfusion according MspI polymorphisms alpha-2A-adrenergic receptor gene (ADRA2A) children with ADHD. Methods Thirty seven drug-naive ADHD (8.9+1.8 years old, M=32, F=5) were genotyped. Baseline single-photon emission computed tomography (SPECT) clinical assessments...
Abstract There are a number of epidemiological studies concerning the gender differences in genetic etiology alcohol dependence (AD), with ADH2 and ALDH2 being strong candidates. The purpose this study was to investigate frequencies genotypes AD patients normal control (NC) group Koreans. Study subjects consisted 228 (180 males, 48 females) 138 NC (79 59 females). For both male female subjects, frequency ADH2*1/1 genotype significantly higher compared group. However, effect size on much...
Alcohol has been used as sedatives historically. The effect of alcohol on sleep is different according to its dose, timing ingestion, and drinking frequency. Sleep problems may play a role in the development course alcohol-related disorders. Insomnia alcohol-dependent patients common early treatment insomnia reduce rate relapse. apnea, restless legs syndrome, periodic limbs movement disorder, altered circadian rhythm be more frequent this patients. Management important treating disorder...
Objectives : Repetitive and stereotyped behaviors are core symptoms in children with autism spectrum disorders (ASD). The purpose of our study was to investigate the frequency motor stereotypes ASD their clinical features. Methods Among 171 (age range, 3-15), group defined according two items Korean version Autism Diagnostic Interview-Revised (K-ADI-R). We compared features, behavior problems severity other domains K-ADI-R executive functions between without stereotypes. Results Ninety...
Young-Jin Koo, Jun-Won Hwang, Moon-Soo Lee, Young-Hui Yang, Soo-Young Bang, Je-Wook Kang, Dae-Hwan Ju-Hyun Young-Sook Kwack, Seungtai Peter Kim, Kyung Sun Noh, Sung-Sook Park, Geon Ho Bahn, Dong-Ho Song, Dong Hyun Ahn, Young Sik Jeong-Seop Soo-Churl Cho, and Kang-E Michael Hong. J Korean Acad Child Adolesc Psychiatry 2016;27:2-30. https://doi.org/10.5765/jkacap.2016.27.1.2
Young-Hui Yang, Jun-Won Hwang, Boong-Nyun Kim, Hyejin Kang, Jae-Sung Lee, Dong-Soo and Soo-Churl Cho. J Korean Acad Child Adolesc Psychiatry 2016;27:64-71. https://doi.org/10.5765/jkacap.2016.27.1.64
Raising awareness of the dangers drugs is one most effective means preventing addiction.This qualitative study was conducted to provide approachable and truly illustrative examples depredations substance use among celebrities.The authors' analyzed deaths related defined their causes through thematic analysis as external such accidents suicide or internal medical complications.The ten due lethal overdoses were compulsive use, which according diagnostic criteria DSM-5 diagnosed...
Objectives The aim of this study was to examine whether the presence risk alleles norepinephrine transporter gene (SLC6A2) polymorphisms is associated with differences in regional cerebral blood flow (rCBF) measured by 99m Tc-HMPAO single photon emission computerized tomography a Korean sample ADHD. Methods present included 24 children ADHD (9.5±2.4 years), consisting 20 boys and 4 girls, aged 6-16 years. We investigated G1287A -3081(A/T) SLC6A2. rCBF compared between subjects without at...
The purpose of this study was to examine the reliability and validity Korean version Behavior Problems Inventory (BPI-01) among children adolescents aged between 3 18.