A5059692607- Attention Deficit Hyperactivity Disorder
- Autism Spectrum Disorder Research
- Functional Brain Connectivity Studies
- Family and Disability Support Research
- Child and Adolescent Psychosocial and Emotional Development
- Child Nutrition and Feeding Issues
- Obsessive-Compulsive Spectrum Disorders
- Genetics and Neurodevelopmental Disorders
- Advanced Neuroimaging Techniques and Applications
- Bipolar Disorder and Treatment
- Child Development and Digital Technology
- Mental Health Research Topics
- Infant Development and Preterm Care
- Digital Mental Health Interventions
- Cognitive Abilities and Testing
- Maternal Mental Health During Pregnancy and Postpartum
- Eating Disorders and Behaviors
- Attachment and Relationship Dynamics
- Psychosocial Factors Impacting Youth
- Impact of Technology on Adolescents
- Health, Environment, Cognitive Aging
- Neural and Behavioral Psychology Studies
- Morphological variations and asymmetry
- 3D Shape Modeling and Analysis
- Diverse Approaches in Healthcare and Education Studies
Seoul National University Hospital
2010-2025
Seoul National University
2012-2025
Seoul National University Children's Hospital
2024
New Generation University College
2022
Seoul National University of Education
2016
Seoul National University Bundang Hospital
2013-2016
Konyang University Hospital
2016
The University of Melbourne
2013-2014
Florey Institute of Neuroscience and Mental Health
2014
Melbourne Health
2013-2014
Fractal dimension (FD) has been widely used to provide a quantitative description of structural complexity in the cerebral cortex. FD is an extremely compact measure shape complexity, condensing all details into single numeric value. We interpreted variation cortical surface normal controls through multiple regression analysis with thickness, sulcal depth, and folding area related complexity. showing reliable representation folded gyri manually parcellated it frontal, parietal, temporal,...
Abstract Background The orbitofrontal cortex (OFC) has consistently been implicated in the pathology of both drug and behavioral addictions. However, no study to date examined OFC thickness internet addiction. In current study, we investigated existence differences cortical adolescents with On basis recently proposed theoretical models addiction, predicted a reduction addicted individuals. Findings Participants were 15 male diagnosed as having addiction healthy comparison subjects. Brain...
Background Bisphenol A ( BPA ) has been shown to affect brain and behavior in rodents nonhuman primates, but there are few studies focusing on its relationship human neurobehavior. We aimed investigate the between environmental exposure childhood Methods Urinary concentrations behavioral learning characteristics were assessed a general population of 1,089 children, aged 8–11 years. The main outcome measures Child Behavior Checklist CBCL Learning Disability Evaluation Scale LDES ). Results...
Objectives: This study examined the neurocognitive profiles of early adulthood attention-deficit/hyperactivity disorder (ADHD) patients using Korean version Wechsler Adult Intelligence Scale, 4th Edition (K-WAIS-IV) and Continuous Performance Test 3rd (CPT-3) assessment results.Methods: A total 105 individuals underwent K-WAIS-IV assessment, 68 participants completed CPT-3.We differences between intelligence subindex scores paired t-tests applied Pearson's correlation analysis to determine...
Importance Light pollution’s impact on human health is increasingly recognized, but its link to exudative age-related macular degeneration (EAMD) remains unclear. Objective To investigate the association between exposure outdoor artificial light at night (OALAN) and risk of incident EAMD. Design, Setting, Participants In this nationwide population-based case-control study, all individuals 50 years or older with newly diagnosed EAMD January 1, 2010, December 31, 2011, were identified...
Lack of quantifiable biomarkers is a major obstacle in diagnosing and treating depression. In adolescents, increasing suicidality during antidepressant treatment further complicates the problem.We sought to evaluate digital for diagnosis response depression adolescents through newly developed smartphone app.We Smart Healthcare System Teens At Risk Depression Suicide app Android-based smartphones. This passively collected data reflecting social behavioral activities such as their usage time,...
This study examined the validity of Childhood Autism Rating Scale, Second Edition (CARS-2) compared with Diagnostic Observation Schedule, (ADOS-2) in identifying autism spectrum disorder (ASD).A total 237 children were tested using both CARS-2 and ADOS-2. We correlation Pearson's analysis. In addition, we used a receiver operating characteristic graph to determine optimal standard version (CARS2-ST) cutoff score for ASD diagnosis ADOS-2.The concurrent CARS2-ST was demonstrated by significant...
Importance Joint attention, composed of complex behaviors, is an early-emerging social function that deficient in children with autism spectrum disorder (ASD). Currently, no methods are available for objectively quantifying joint attention. Objective To train deep learning (DL) models to distinguish ASD from typical development (TD) and differentiate symptom severities using video data attention behaviors. Design, Setting, Participants In this diagnostic study, tasks were administered...
We examined the cross-sectional relationship between environmental tobacco smoke exposure, continuous performance test (CPT) measures, and attention deficit hyperactivity disorder (ADHD) or learning disability symptoms in school-aged children.In total, 989 children (526 boys, mean age 9.1 ± 0.7 years), recruited from five South Korean cities participated this study. used urine cotinine as a biomarker for obtained children's scores on CPT. Parents completed versions of ADHD rating scale-IV...
Background We investigated the distinct longitudinal trajectories of posttraumatic stress symptoms in a sample 167 children, who witnessed death two mothers their schoolmates. Methods The cohort was followed‐up at 2 days (T1), months (T2), 6 (T3), and 30 (T4) after traumatic event. children's (T1–T4), depression (T1, T3 T4), state anxiety quality life were assessed, along with parental related to child rearing (T4). Different trajectory patterns identified using growth mixture modeling ( GMM...
Few studies have empirically tested the relationships between anatomically defined thalamic nuclei and functionally cortical networks, little is known about their implications in attention-deficit/hyperactivity disorder (ADHD). This study aimed to investigate functional connectivity of thalamus youth with ADHD, using both seed regions.Resting-state MRIs obtained from publicly available ADHD-200 database were analyzed. Thalamic regions based on Yeo's 7 resting-state-network parcellation atlas...
Dysregulation of noradrenergic system may play important roles in pathophysiology attention-deficit/hyperactivity disorder (ADHD). We examined the relationship between polymorphisms norepinephrine transporter SLC6A2 gene and attentional performance before after medication children with ADHD.Fifty-three medication-naïve ADHD were genotyped evaluated using continuous test (CPT). After 8-weeks methylphenidate treatment, these by CPT again. compared baseline measures post-treatment changes based...
The Children's Depression Rating Scale-Revised (CDRS-R) is a valid instrument for the assessment of depressive symptoms in youth, but this measure yet to be validated Korea. Thus, present study aimed evaluate validity Korean version CDRS-R and determine its factor structures.This included 66 youths between 12 17 years age who participated as part an ongoing investigating biomarkers antidepressant response suicidal events depressed youth. At baseline, participants were assessed using...
The authors examined the association between MspI C/G and DraI C/T genotypes of α2A-adrenergic receptor gene white-matter connectivity attentional performance before after medication in 53 children with attention-deficit hyperactivity disorder. Subjects who carried T allele at polymorphism showed fewer changes mean commission error scores 8 weeks decreased fractional anisotropy (FA) values right middle frontal cortex than subjects without allele. C FA postcentral gyrus without.
Tic disorders are highly heritable; however, growing evidence suggests that environmental factors play a significant role in their pathogenesis. Studies on these have been inconsistent, with conflicting results. Therefore, this study aimed to examine the associations of pre- and perinatal exposure Tourette syndrome (TS) or chronic tic (CTD) Korean school-aged children.This case-control used data from large prospective cohort study. The primary outcome was TS/CTD diagnosis according...
According to the 10th revision of International Classification Diseases, main categories tic disorders (F95.0, F95.1, and F95.2) follow a diagnostic hierarchy based on duration diversity symptoms. The present study investigated use this in real-world clinical practice.Based National Health Insurance Service-National Information Database, diagnosis transient disorder (F95.0) made after chronic motor or vocal (F95.1) Tourette's syndrome (F95.2) were referred as type A errors. repeated period...
Background In children with autism spectrum disorder (ASD), problem behaviors play a dysfunctional role, causing as much difficulty daily living and adjustment the core symptoms. If such are not effectively addressed, they can result in physical, economic, psychological issues only for individual but also family members. Objective We aimed to develop evaluate feasibility of mobile app–assisted parent training program reducing ASD. Methods This open-label, single-center, randomized controlled...
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