A5100680314- Cardiovascular Function and Risk Factors
- Ultrasound in Clinical Applications
- Cardiovascular Effects of Exercise
- Cardiac Imaging and Diagnostics
- Pulmonary Hypertension Research and Treatments
- Cardiomyopathy and Myosin Studies
- Cardiac Structural Anomalies and Repair
- Coronary Interventions and Diagnostics
- Lung Cancer Diagnosis and Treatment
- Cardiac Valve Diseases and Treatments
- Gastrointestinal motility and disorders
- Mechanical Circulatory Support Devices
- Gastroesophageal reflux and treatments
- Sarcoidosis and Beryllium Toxicity Research
- Cancer Treatment and Pharmacology
- Viral Infections and Immunology Research
- Cardiac pacing and defibrillation studies
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Ultrasound and Hyperthermia Applications
- Extracellular vesicles in disease
- Cholesterol and Lipid Metabolism
- Protein Degradation and Inhibitors
- RNA modifications and cancer
- Bioenergy crop production and management
- Cardiovascular Disease and Adiposity
Shanxi Agricultural University
2024
Cornell University
2024
Fujian Medical University
2024
Union Hospital
2024
Beijing Chao-Yang Hospital
2017-2023
Yang Hospital
2023
Capital Medical University
2017-2023
Beijing Chaoyang Emergency Medical Center
2018-2021
Beth Israel Deaconess Medical Center
2020
Truven Health Analytics (United States)
2016-2018
Little real-world evidence is available to describe the recent trends in treatment costs and outcomes for patients with multiple myeloma (MM). Using Truven Health MarketScan Research Databases linked social security administration death records, this study found that percentage of MM using novel therapy continuously increased from 8.7% 2000 61.3% 2014. Compared diagnosed earlier years, those after 2010 had higher rates use better survival outcomes; 2012 were 1.25 times more likely survive 2...
Background: Extracellular vesicles (EVs) are considered a promising drug delivery platform.Naïve EVs face numerous issues that limit their applications, such as fast clearance, hepatic accumulations, and lack of target-specific tropism.We aimed to explore series surface engineering approaches to: 1) reduce the non-specific adhesion EVs, 2) improve enrichment in target tissue.As proof-of-concept, we investigated therapeutic potentials multi-modal system carrying tumor-specific nanobody...
Ultrasound lung comets (ULCs) are a nonionizing bedside approach to assess extravascular water. We evaluated protocol for grading ULC score estimate pulmonary congestion in heart failure patients and investigated clinical echocardiographic correlates of the score. Ninety-three with congestive failure, admitted emergency department, underwent ultrasound echocardiography. A was obtained by summing scores 7 zones anterolateral chest scans. The results were compared results, New York Heart...
Right ventricular (RV) glucose metabolism disorder in pulmonary arterial hypertension (PAH) has been studied using 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) imaging with inconsistent results. We aimed to quantitatively assess RV and further identify its role of monitoring function idiopathic PAH (IPAH) patients a longitudinal study. Twenty-seven treatment-naïve IPAH 21 healthy control subjects performed FDG-PET dynamic scan for quantification the rate myocardium...
Background Impaired right ventricular ( RV ) function indicates involvement in patients with hypertrophic cardiomyopathy HCM ). We aimed to assess at rest and during exercise examine the association between impaired mechanics capacity. Methods Results A total of 76 (48 without 28 hypertrophy) 30 age- sex-matched controls were prospectively recruited. was evaluated semisupine bicycle by conventional echocardiography 2-dimensional speckle-tracking imaging. Exercise capacity measured metabolic...
Objectives Detection of B-line in dyspneic patients is often accompanied by abnormal changes pleural line on transthoracic ultrasonography (TUS). The aim the study was to evaluate relevance and diagnostic performance abnormalities B-lines detected high-resolution TUS against computed tomography (CT) findings. Methods Transthoracic performed admitted emergency department with dyspnea. accompanying were assessed using a linear transducer. findings corresponding CT same location, which...
Introduction Salt stress is one of the significant challenges in sorghum production, greatly impacting yield S. bicolor . L-type lectin receptor kinases ( LLRKs ) are essential for plant tolerance, yet a comprehensive genome-level analysis this species has not been conducted. Materials and methods Members SbLLRLK gene family were identified using bioinformatics methods. Gene structures, motifs, phylogenetic relationships analyzed. Subsequently, expression profiles under various conditions...
IO Memory protection mechanisms prevent malicious and/or buggy devices from executing errant transfers into memory. Modern servers achieve this using an IOMMU---IO operate on virtual addresses, and IOMMU translates addresses to physical (potentially speeding up translations a cache called IOTLB) before memory transfers. Despite their importance, design of that can provide strong safety properties while achieving high performance has remained elusive. Indeed, recent studies production...
Although catheter ablation (CA) is an effective treatment for non-valvular atrial fibrillation (AF), a good many of patients still have recurrence following post-operation. Prediction AF by evaluating left (LA) phase function with speckle tracking echocardiography (STE) may be helpful risk stratification and clinical management patients. Therefore, the current study aimed to assess prognostic value LA strains in after CA.A total 95 (70.5% paroxysmal AF, 56.8% males, mean age 63.2 ± 9.7...
Reduced metabolic equivalents (METs) are an indicator of exercise intolerance, which predicts poor prognosis in hypertrophic cardiomyopathy (HCM) patients. We sought to evaluate the changes left ventricular (LV) mechanics and functional reserves, as well their association with capacity HCM patients.Seventy patients thirty controls were included this study. LV evaluated at rest during by echocardiography two-dimensional speckle-tracking imaging obtain parameters reserve, global longitudinal...
Abstract Background During early systole, ischemic myocardium with reduced active force experiences systolic lengthening (ESL). This study aimed to explore the diagnostic potential of myocardial ESL in suspected non-ST-segment elevation acute coronary syndrome (NSTE-ACS) patients normal wall motion and left ventricular ejection fraction (LVEF). Methods Overall, 195 NSTE-ACS LVEF, who underwent speckle tracking echocardiography (STE) before angiography, were included this study. Patients...
Right ventricular (RV) contractile reserve reflects the ability of RV to accommodate increased afterload and may play an essential role in evaluation precapillary pulmonary hypertension (PH). This study aimed assess based on exercise stress echocardiography (ESE) determine echocardiographic determinants capacity patients with PH.A total 31 PH 15 age- sex-matched healthy control subjects were prospectively recruited. All underwent ESE function at rest under peak exercise. Changes these...
Abstract Introduction The left atrial (LA) strain and rate are sensitive indicators of LA function. However, they not widely used for the evaluation pregnant women with metabolic diseases. aim this study was to assess clustering risk factors explore its prognostic effect on adverse pregnancy outcomes. Materials methods Sixty-three a (CMR group), fifty-seven pregnancy-induced hypertension (PIH gestational diabetes mellitus (GDM fifty matched healthy (control group) were retrospectively...
Pleural effusion (PE) drainage can relieve the symptoms of dyspnea; however, details resulting hemodynamic changes remain undefined. Subjects older than 12 years with massive PE requiring pleural were included in this study. Hemodynamic parameters collected using transthoracic echocardiography at pre-drainage, immediately post-drainage, and 24 h after drainage. We enrolled 47subjects prospective study from June 9, 2015 to September 18, 2016 Beijing Chaoyang Hospital 28 subjects analyzed...
Severe cardiac sarcoidosis (CS) can share clinical and histopathologic features with giant cell myocarditis (GCM).A 56-year-old female presented 1 week of exertional chest pressure dyspnoea. Echocardiogram demonstrated extensive regional dysfunction left ventricular ejection fraction (LVEF) 38%. Cardiac catheterization revealed no obstructive coronary artery disease index 1.5 L/min/m2. magnetic resonance imaging (MRI) diffuse late gadolinium enhancement. Positron emission tomography...
Abstract Background Obstructive sleep apnea syndrome (OSAS) is associated with various cardiovascular diseases and has aroused public concern. Early detection for declining myocardial function of great significance. This study was aimed at noninvasively evaluating the subclinical left ventricular (LV) dysfunction LV pressure–strain loop (PSL) in patients OSAS having normal ejection fraction. Methods We enrolled 200 who visited Beijing Chaoyang Hospital between February 2021 December 2021....
Biomass yield is one of the important traits sorghum, which greatly affected by leaf morphology. In this study, a lobed-leaf mutant (sblob) was screened and identified, its F2 inbred segregating line constructed. Subsequently, MutMap whole-genome sequencing were employed to identify candidate gene (sblob1), locus Sobic.003G010300. Pfam homologous analysis indicated that sblob1 encodes Cytochrome P450 protein plays crucial role in plant serotonin/melatonin biosynthesis pathway. Structural...