Marcel Koenigkam Santos

ORCID: 0000-0002-7160-4691
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About
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Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Advanced MRI Techniques and Applications
  • MRI in cancer diagnosis
  • Atomic and Subatomic Physics Research
  • Pleural and Pulmonary Diseases
  • Medical Imaging Techniques and Applications
  • COVID-19 Clinical Research Studies
  • Cardiomyopathy and Myosin Studies
  • Cardiac Structural Anomalies and Repair
  • Cardiovascular Function and Risk Factors
  • Trypanosoma species research and implications
  • Cardiac tumors and thrombi
  • Long-Term Effects of COVID-19
  • Ultrasound in Clinical Applications
  • Cardiac Imaging and Diagnostics
  • Advanced X-ray and CT Imaging
  • Tracheal and airway disorders
  • Pulmonary Hypertension Research and Treatments
  • Medical Imaging and Pathology Studies
  • COVID-19 diagnosis using AI
  • Neonatal Respiratory Health Research
  • Radiology practices and education

Universidade de São Paulo
2015-2025

Universidade de Ribeirão Preto
2013-2024

Universidade Sagrado Coração
2023

Caesars Entertainment (United States)
2023

Clinics Hospital of Ribeirão Preto
2013-2022

Universidade Brasil
2008-2019

Heidelberg University
2012-2017

University Hospital Heidelberg
2012-2017

German Center for Lung Research
2013-2017

German Cancer Research Center
2013-2015

lung cancer is the leading cause of cancer-related deaths in world, and its poor prognosis varies markedly according to tumor staging. Computed tomography (CT) imaging modality choice for evaluation, being used diagnosis clinical Besides stage, other features, like histopathological subtype, can also add prognostic information. In this work, radiomics-based CT features were predict histopathology metastases using machine learning models.local image datasets confirmed primary malignant...

10.1016/j.cmpb.2018.02.015 article EN publisher-specific-oa Computer Methods and Programs in Biomedicine 2018-02-27

We conducted a prospective cohort study in population with diverse ethnic backgrounds from Brazil to assess clinically meaningful symptoms after surviving coronavirus disease. For most of the 175 patients study, symptoms, including fatigue, dyspnea, cough, headache, and muscle weakness, persisted for >120 days disease onset.

10.3201/eid2803.212020 article EN cc-by Emerging infectious diseases 2022-02-16

COVID-19 has affected more than half a billion people worldwide, with 6.3 million deaths, but the pathophysiological mechanisms involved in lethal cases and host determinants that determine different clinical outcomes are still unclear. In this study, we assessed lung autopsies of 47 patients examined inflammatory profiles, viral loads, inflammasome activation. Additionally, correlated these factors patient’s histopathological conditions. Robust activation was detected lungs SARS-CoV-2....

10.1371/journal.ppat.1012222 article EN cc-by PLoS Pathogens 2024-06-05

<i>Objectives:</i> To measure olfactory bulbs and sulci using dedicated magnetic resonance imaging (MRI) sequences specific measurement tools in Kallmann syndrome (KS) patients with a well-established genotype phenotype, as well correlate MRI findings clinical smell test. <i>Methods:</i> was performed 21 KS 16 healthy volunteers; dysfunction assessed the Smell Identification Test (UPSIT), qualitative suprathreshold olfaction Coronal turbo spin echo T2-weighted...

10.1159/000328437 article EN Neuroendocrinology 2011-01-01

Background: Noninvasive diagnosis of giant cell arteritis (GCA) remains challenging, particularly with regard to evaluation extracranial arterial disease. Objectives: The objective the study was retrospectively review involvement in patients GCA and/or polymyalgia rheumatica (PMR), evaluated magnetic resonance imaging (MRI), especially 3-dimensional contrast-enhanced angiography images aortic arch and its branches. Methods: Clinical information, biopsy status, MRI examinations 28 GCA/PMR...

10.1097/rhu.0b013e31822acec6 article EN JCR Journal of Clinical Rheumatology 2011-09-01

Objectives Quantitative multidetector computed tomography (MDCT) as a potential biomarker is increasingly used for severity assessment of emphysema in chronic obstructive pulmonary disease (COPD). Aim this study was to evaluate the user-independent measurement variability between five different fully-automatic densitometry software tools. Material and Methods MDCT full-body plethysmography incl. forced expiratory volume 1s total lung capacity were available 49 patients with advanced COPD...

10.1371/journal.pone.0112898 article EN cc-by PLoS ONE 2014-11-11

Background: Cardiac tumors are extremely rare; however, when there is clinical suspicion, proper diagnostic evaluation necessary to plan the most appropriate treatment.In this context, cardiovascular magnetic resonance imaging (CMRI) plays an important role, allowing a comprehensive characterization of such lesions.Objective: To review cases referred CMRI Department for investigation cardiac and paracardiac masses.To describe positive case series with brief literature each type lesion role...

10.5935/abc.20130150 article EN cc-by-nc Arquivos Brasileiros de Cardiologia 2013-01-01

Abstract Objective: To explore the feasibility of two magnetic resonance imaging (MRI) sequences—high-resolution T2-weighted (HR T2) and Look-Locker T1 (LL T1) relaxometry—for investigation focal lung lesions (FLLs). As a secondary objective, we analyzed diagnostic accuracy these sequences. Materials Methods: This was prospective observational study involving 39 subjects with FLLs scanned in 1.5-T MRI system LL relaxometry HR T2 sequences focused on FLL region, addition to conventional...

10.1590/0100-3984.2024.0033 article EN Radiologia Brasileira 2024-01-01

Magnetic resonance imaging (MRI) has several advantages in the evaluation of cancer patients with thoracic lesions, including involvement chest wall, pleura, lungs, mediastinum, esophagus and heart. It is a quite useful tool diagnosis, staging, surgical planning, treatment response follow-up these patients. In present review, authors contextualize relevance MRI lesions Considering that widely available method high contrast spatial resolution without risks associated use ionizing radiation,...

10.1590/0100-3984.2013.1921 article EN Radiologia Brasileira 2015-02-01

Androgens have been reported to elongate telomeres in retrospective and prospective trials with patients telomeropathies, mainly bone marrow failure. In our single-arm clinical trial (clinicaltrials gov. Identifier: NCT02055456), 17 short and/or germline pathogenic variants telomere biology genes associated at least one cytopenia radiologic diagnosis of interstitial lung disease were treated 5 mg/kg intramuscular nandrolone decanoate every 15 days for 2 years. Ten 13 evaluable (77%) showed...

10.3324/haematol.2022.281808 article EN cc-by-nc Haematologica 2022-12-29
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