A5101915114- Epilepsy research and treatment
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Functional Brain Connectivity Studies
- Multiple Sclerosis Research Studies
- Cerebrovascular and Carotid Artery Diseases
- Neuroscience and Neuropharmacology Research
- Pharmacological Effects and Toxicity Studies
- Fetal and Pediatric Neurological Disorders
- Neonatal and fetal brain pathology
- Cerebrospinal fluid and hydrocephalus
- MRI in cancer diagnosis
- Glioma Diagnosis and Treatment
- Parasitic infections in humans and animals
- Neurological disorders and treatments
- Vestibular and auditory disorders
- Pituitary Gland Disorders and Treatments
- Head and Neck Surgical Oncology
- Meningioma and schwannoma management
- Peripheral Neuropathies and Disorders
- Intracranial Aneurysms: Treatment and Complications
- Dementia and Cognitive Impairment Research
- Systemic Lupus Erythematosus Research
- Parasite Biology and Host Interactions
- Traumatic Brain Injury and Neurovascular Disturbances
Universidade de São Paulo
2015-2024
Cooperativa de Ensino Superior Politécnico e Universitário
2024
Universidade Federal de Lavras
2017-2023
Clinics Hospital of Ribeirão Preto
2014-2023
Universidade de Ribeirão Preto
2013-2023
Instituto de Filosofía
2023
Instituto de Neurociências e Comportamento
2016-2022
Hospital de Clínicas
2020
Escuela Superior de Guerra
2020
Universidade Federal de Sergipe
2018
The experiences induced by psychedelics share a wide variety of subjective features, related to the complex changes in perception and cognition this class drugs. A remarkable increase introspection is at core these altered states consciousness. Self-oriented mental activity has been consistently linked Default Mode Network (DMN), set brain regions more active during rest than execution goal-directed task. Here we used fMRI technique inspect DMN psychedelic state Ayahuasca ten experienced...
Parkinson's disease (PD) has a progressive course and is characterized by the degeneration of dopaminergic neurons. Although no neuroprotective treatments for PD have been found to date, endocannabinoid system emerged as promising target.From sample 119 patients consecutively evaluated in specialized movement disorders outpatient clinic, we selected 21 without dementia or comorbid psychiatric conditions. Participants were assigned three groups seven subjects each who treated with placebo,...
<h3>Background</h3> Fatigue is a common and distressing symptom for patients with multiple sclerosis (MS). There growing evidence that fatigue in MS has central nervous system component. We hypothesized diffuse cerebral axonal damage could be associated used proton magnetic resonance spectroscopy to noninvasively measure or loss the brains of MS. <h3>Objective</h3> To assess strength relationship between brain<i>N</i>-acetylaspartate fatigue. <h3>Design</h3> Data from 73 who had undergone...
Until recently, neuromyelitis optica (NMO) was considered to be a sub-type of multiple sclerosis (MS), which has strong predilection for Caucasian populations, whereas NMO is more frequent in non-Caucasian individuals. The objective this study compare the HLA-DRB profile Brazilian Mulatto patients with spectrum disorders (NMOSDs) that observed MS and healthy controls. Twenty seven NMOSD (20 women), all seropositive NMO-IgG, 29 28 blood donors were evaluated allele groups. HLA-DRB1*03 group...
Background: Structural brain abnormalities in schizophrenia have been repeatedly demonstrated magnetic resonance imaging (MRI) studies, but it remains unclear whether these are static or progressive nature. While longitudinal MRI studies traditionally used to assess the issue of progression schizophrenia, information from cross-sectional neuroimaging directly comparing first-episode and chronic patients healthy controls may also be useful further clarify this issue. With recent interest...
Alzheimer's disease (AD) is a primary and progressive neurodegenerative disorder, which marked by cognitive deterioration memory impairment. Atrophy of hippocampus other basal brain regions one the most predominant structural imaging findings related to AD. Most studies have evaluated pre-clinical initial stages AD through clinical trials using Magnetic Resonance Imaging. Structural biomarkers for advanced not been yet, being considered only hypothetically. To evaluate morphometry patients...
A quantitative magnetization transfer imaging (qMTI) study, based on a two-pool model of transfer, was performed seven normal subjects to determine, regional basis, values for the pool sizes, exchange, and relaxation parameters that characterize MT phenomenon. Regions were identified high-resolution anatomical scans using combination manual automatic methods. Only voxels as pure tissue at resolution considered analysis. While no left/right differences observed, significant found among...
Traumatic brain injury (TBI) is a classic model of monophasic neuronal and axonal injury, in which tissue damage mainly occurs at the moment trauma. There some evidence delayed progression loss. Our purpose was to test hypothesis that quantitative MR imaging techniques can estimate biologic changes secondary loss after TBI.Nine patients (age, 11-28 years; 5 male) who sustained moderate or severe TBI were evaluated mean 3.1 years We applied following techniques: bicaudate (BCR) bifrontal...
Regional cerebral blood flow (CBF) and cerebrovascular reactivity (CVR) in young elderly participants were assessed using pulsed arterial spin labeling (ASL) oxygenation level-dependent (BOLD) magnetic resonance imaging (MRI) techniques combination with inhalation of CO2. Pulsed ASL BOLD-MRI acquired seventeen asymptomatic volunteers (10 adults, age: 30±7 years; 7 64±8 years) no history diabetes, hypertension, neurological diseases. Data from one participant was excluded due to the...
We estimated the incidence of first-episode psychosis over a 3-year period in Brazilian catchment area comprising region's main city, Ribeirão Preto (1 425 306 persons-years at risk), and 25 other municipalities with total 1 646 556 risk. The rates were adjusted by gender age, using direct standardisation method to world population as reference. was higher younger groups, men, among Black minority ethnic Brazilians. Psychosis lower (16.69/100 000 person-years risk; 95% CI 15.68–17.70)...
Twelve to 66% of patients with clinically non-functioning pituitary adenoma (NFPA) experience tumor recurrence 1-5 years after the first surgery. Nevertheless, there is still no prediction factor concisely established and reproduced in literature for NFPA management. The present study evaluates prognostic value MRI Radiomics features combined machine learning models assess surgery adenomas (NFPA). We carried out a retrospective on 27 NFPA, 10 having experienced 17 who did not. Preoperative...
Importance: Owing to its anti-inflammatory properties and antiviral "in vitro" effect against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), cannabidiol (CBD) has been proposed as a potential treatment for disease 2019 (COVID-19).
Temporal lobe epilepsy (TLE) is the most common type of focal and frequently drug-resistant (DR) to antiseizure medication (ASM), corresponding approximately one-third cases. When left inadequately treated, it can worsen quality life, cognitive deficits, risk death. The standard treatment for TLE surgical removal structures involved, with good long-term outcome rates 60-70 % a low rate adverse effects. goal successful sustained seizure freedom. In our study, we evaluated (up 23 years)...
<b><i>Background:</i></b> Several studies suggest that neurocysticercosis is the main cause of symptomatic epilepsy in developing countries. In such areas, calcified cysticercotic lesions (CCL) are frequently found patients with complex partial seizures associated hippocampal sclerosis (HS). The authors studied whether there clinical and pathologic differences between HS without CCL. <b><i>Methods:</i></b> determined findings 30 compared them 32 + Hippocampi from both groups were measured...