A5030380244- Emergency and Acute Care Studies
- Food Security and Health in Diverse Populations
- Obesity, Physical Activity, Diet
- Health disparities and outcomes
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Education
- Nutritional Studies and Diet
- Diabetes Management and Research
- Disaster Response and Management
- Cardiac Arrest and Resuscitation
- Chronic Disease Management Strategies
- Diabetes and associated disorders
- COVID-19 and healthcare impacts
- Data-Driven Disease Surveillance
- COVID-19 Clinical Research Studies
- Trauma and Emergency Care Studies
- Primary Care and Health Outcomes
- Monoclonal and Polyclonal Antibodies Research
- Smoking Behavior and Cessation
- Musculoskeletal pain and rehabilitation
- Reproductive tract infections research
- Long-Term Effects of COVID-19
- HER2/EGFR in Cancer Research
- Disaster Management and Resilience
- Homelessness and Social Issues
New York University
2016-2025
Bellevue Hospital Center
2020-2025
NYU Langone Health
2024
New York City Department of Health and Mental Hygiene
2020
University of Pennsylvania
2015
Thomas Jefferson University
2015
North Shore University Hospital
1998-2014
Singapore Management University
2014
Robert Wood Johnson Foundation
2014
San Francisco Foundation
2005-2007
Metallothionein-directed expression of TGF alpha in transgenic mice induced a spectrum changes the growth and differentiation certain adult tissues. First, promoted uniform epithelial hyperplasia several organs without otherwise causing major alterations tissue architecture. Second, pancreas it proliferation both acinar cells fibroblasts focally altered cell differentiation. The magnitude this response was proportional to level local, tissue-specific reproduced when placed under control...
Cerebral and myocardial ischemia, two of the leading causes morbidity mortality worldwide, are associated with inflammation that can lead to multiple organ failure death. High-mobility group box 1(HMGB1), a recently described mediator lethal systemic inflammation, has been detected in individuals severe sepsis hemorrhagic shock, but its role during ischemic injury humans is unknown. To determine whether HMGB1 levels elevated after injury, prospective observational study was performed...
MQn6trier's disease is an uncommon disorder of unknown etiology characterized by enlarged gastric folds with foveolar hyperplasia and cystic dilatation glands.Biochemical features that are seen frequently include hypoproteinemia, hypochlorhydria, increased mucus.Because transforming growth factor a (TGFa) epithelial cell mitogen inhibits acid secretion increases mucin content, we hypothesized its altered expression might be involved in the pathogenesis this disease.Therefore, TGFa...
Transferrin-specific cDNA clones were isolated from a rat liver library prepared transferrin-enriched mRNA. Hybrid selection and sequence analysis confirmed that the selected clone contained carboxy-terminal coding region of transferrin Northern blot was used to demonstrate presence mRNA in Sertoli cells. Transferrin levels measured total RNA cultured cells after treatment with FSH, insulin, retinol, testosterone. The results showed 2- 4-fold increase level mRNA, which peaked on fourth day...
Abstract Objective Injury‐related morbidity and mortality is an important emergency medicine public health challenge in the United States. Here we describe epidemiology of traumatic injury presenting to U.S. departments ( ED s), define changes types causes among elderly young, characterize role trauma centers teaching hospitals providing care, estimate overall economic burden treating such injuries. Methods We conducted a secondary retrospective, repeated cross‐sectional study Nationwide...
ABSTRACT Objective Older adults are a potentially medically vulnerable population with increased mortality rates during and after disasters. To evaluate the impact of natural disaster on this population, we performed temporal geospatial analysis emergency department (ED) use by aged 65 years older in New York City (NYC) following Hurricane Sandy’s landfall. Methods We used an all-payer claims database to analyze demographics, insurance status, geographic distribution, health conditions for...
This study investigated the benefits of cultural exposure for transracially adopted (TRA) Korean children's developmental understanding being Korean. Fifty TRA children living in United States were interviewed to assess their implications status peer relations and personal identities, using a model perspective-taking ability (PTA). Results showed chronological age significant predictors PTA Cultural had slightly stronger relationship with development younger than older ones. Comparison...
ABSTRACT Background Annexin A2 is a phospholipid-binding protein involved in fibrinolysis, cell membrane stabilization and repair, ensuring the integrity of pulmonary microvasculature. Given autoantibodies observed COVID-19 that known target antiphospholipid antibodies, we studied autoimmunity directed against among hospitalized patients. Methods We used ELISA to identify levels IgG recognizing A5 86 cases COVID-19. Using logistic regression, analyzed association between anti-Annexin...
The Singapore housing market is unusual in its high homeownership rate, the dominance of HDB housing, and extensive intervention government regulating supply demand both private sectors. Recent rapid population increases a low interest rate global liquidity environment has resulted accelerated house prices Singapore. Earlier this year, launched "Our Conversation" which discussion on policies constitutes one major component. This "conversation" comes wake several consecutive rounds measures...
We aimed to characterize the geographic distribution of post-Hurricane Sandy emergency department use in administrative flood evacuation zones New York City.Using claims data, we identified significant deviations after Hurricane Sandy. Using time-series analysis, analyzed frequency visits for specific conditions and comorbidities identify medically vulnerable populations who developed acute postdisaster medical needs.We found statistically decreases overall post-Sandy City but increased...
Two independent cDNA clones corresponding to a 2.7-kilobase (kb) epidermal growth factor receptor (EGF-R) mRNA were isolated from rat liver library. Sequence analysis revealed 100% homology in the external domain when compared with full-length EGF-R nucleotide sequence and 80 90% similarity relative human EGF-R. However, 3'-terminal of these did not match or any other known sequence(s) was distinct 3' end 2.8-kb mRNA, which encodes truncated A431 cells. The deduced amino acid an open reading...
The World Health Organization recommends periodic mass antibiotic distributions to reduce the ocular strains of chlamydia that cause trachoma, world's leading infectious blindness. Their stated goal is control infection, not completely eliminate it. A single distribution can dramatically prevalence infection. However, if infection eliminated in every individual community, it may gradually return back into so often repeated treatments are necessary. Since public health groups reluctant...
Objective To evaluate the acute impact of disasters on diabetic patients, we performed a geospatial analysis emergency department (ED) use by New York City adults in week after Hurricane Sandy. Research design and methods Using an all-payer claims database, retrospectively analyzed demographics, insurance status, medical comorbidities post-disaster ED patients with diabetes who lived most geographically vulnerable areas. We compared patterns among first Sandy's landfall to utilization before...
High levels of autoimmune antibodies are observed in COVID-19 patients but their specific contribution to disease severity and clinical manifestations remains poorly understood. We performed a retrospective study 115 hospitalized with different degrees analyze the generation common antigens: lysate erythrocytes, lipid phosphatidylserine (PS) DNA. IgG autoantibodies against erythrocyte lysates were large percentage (up 36%) patients. Anti-DNA anti-PS determined upon hospital admission...
Geographic disparities in diabetes burden exist throughout the United States (US), with many risk factors for clustering at a community or neighborhood level. We hypothesized that likelihood of new onset type 2 (T2D) would differ by three large study samples covering US.
Existing classifications of community type do not differentiate urban cores from surrounding non-rural areas, an important distinction for analyses features and their impact on health. Inappropriately classified types can introduce serious methodologic flaws in epidemiologic studies invalid inferences findings. To address this, we evaluate a modification the United States Department Agriculture's Rural Urban Commuting Area codes at census tract, propose four-level categorization type,...
OBJECTIVE We examined whether relative availability of fast-food restaurants and supermarkets mediates the association between worse neighborhood socioeconomic conditions risk developing type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS As part Diabetes Location, Environmental Attributes, Disparities Network, three academic institutions used harmonized environmental data sources analytic methods in distinct study samples: 1) Veterans Administration Risk (VADR) cohort, a national...
Introduction Traditional survey-based surveillance is costly, limited in its ability to distinguish diabetes types and time-consuming, resulting reporting delays. The Diabetes Children, Adolescents Young Adults (DiCAYA) Network seeks advance efforts youth young adults through the use of large-volume electronic health record (EHR) data. network has two primary aims, namely: (1) refine validate EHR-based computable phenotype algorithms for accurate identification type 1 2 among (2) estimate...
Persistent musculoskeletal pain and psychological sequelae following minor motor vehicle collision (MVC) are common problems with a large economic cost. Prospective studies of MVC have demonstrated that demographic characteristics, including female gender low education level, high pre-collision anxiety, independent predictors persistent pain. These results contributed to the social components biopsychosocial model post-MVC pathogenesis, but biological contributors remain poorly defined....
Although screening for diabetes is recommended at age 45, some populations may be greater risk earlier ages. Our objective was to quantify disparities among patients with type 2 in New York City.Using all-payer hospital claims data City, we performed a cross-sectional analysis of identified from emergency department visits during the 5-year period 2011-2015. We estimated prevalence each year life, distribution stratified by decade, and average sex, race/ethnicity, geographic location.We...