A5083218261- Bone Metabolism and Diseases
- Phytochemical compounds biological activities
- Dermatological and COVID-19 studies
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Bone health and treatments
- Plant-derived Lignans Synthesis and Bioactivity
- Genomics, phytochemicals, and oxidative stress
- T-cell and Retrovirus Studies
- Phytochemicals and Antioxidant Activities
- Cell Adhesion Molecules Research
- Cutaneous lymphoproliferative disorders research
- Protease and Inhibitor Mechanisms
- S100 Proteins and Annexins
Texas Tech University Health Sciences Center
2023
Texas Tech University
2023
Chettinad Health City
2020-2021
Background: Breast cancer (BC) produces bone resorptive cytokines and growth factors which accelerate the development of osteoclasts (OCs), leading to osteolytic metastases. In Long-term Odanacatib Fracture Trial (LOFT), skeletal-metastasized breast subjects who received odanacatib (ODN) had a delayed tumour progression skeletal burden as result anti-resorptive effects through inhibition cathepsin K (CTSK). this study, we explored effect ODN, CTSK inhibitor, on paracrine pro-osteoclast...
Background: Hesperetin is a natural compound known for its cholesterol-lowering effect and wide range of pharmacological activities. Objectives: Investigating the potential anticancer activities in malignant hematolymphoid cell lines HuT78 MJ, derived from patients with Cutaneous T-Cell Lymphomas (CTCL). Methods: The cytotoxic on two different CTCL lines, was assessed by MTS-based colorimetric assay. Apoptosis, cycle, ROS (Reactive Oxygen Species) molecular analysis were performed using...