Thomas C. McHale

ORCID: 0000-0002-7226-3075
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About
Contact & Profiles
Research Areas
  • Mosquito-borne diseases and control
  • COVID-19 epidemiological studies
  • Nail Diseases and Treatments
  • Antifungal resistance and susceptibility
  • Fungal Infections and Studies
  • Climate Change and Health Impacts
  • Viral Infections and Vectors
  • Air Quality and Health Impacts

University of Atlanta
2025

University of Minnesota
2023-2025

University of London
2019

London School of Hygiene & Tropical Medicine
2019

Abstract Background Climate change is anticipated to have profound effects on human health including infectious diseases. Wildfires increased in frequency and intensity due changes precipitation been linked worsening respiratory infections. We aimed demonstrate whether an association existed between wildfire smoke COVID-19 California during 2020. Demographic data by county based the 2020 American Census Survey New York Times mask-use survey conducted July The population of generally higher...

10.1093/ofid/ofae631.2116 article EN cc-by Open Forum Infectious Diseases 2025-01-29

Chikungunya virus (CHIKV) and Zika (ZIKV) have recently emerged as globally important infections. This study aimed to explore the spatiotemporal heterogeneity in occurrence of CHIKV ZIKV outbreaks throughout major international seaport city Barranquilla, Colombia 2014 2016 potential for clustering. Incidence data were fitted using multiple Bayesian Poisson models based on explanatory variables risk factors identified from other studies options random effects. A best fit model was used...

10.3390/ijerph16101759 article EN International Journal of Environmental Research and Public Health 2019-05-18

Abstract Background The EnACT trial was a phase 2 randomized clinical conducted in Uganda, which evaluated novel orally delivered lipid nanocrystal (LNC) amphotericin B combination with flucytosine for the treatment of cryptococcal meningitis. When (5FC) is used as monotherapy cryptococcosis, 5FC can induce resistant Cryptococcus mutants. Oral uses drug delivery mechanism, and we assessed whether resistance to develops during oral LNC–amphotericin therapy. Methods We enrolled Ugandans HIV...

10.1093/ofid/ofad596 article EN cc-by Open Forum Infectious Diseases 2023-11-29

Chikungunya virus (CHIKV) and Zika (ZIKV) have recently emerged as global infections with consequential disability adjusted life years (DALYs) economic burden. This study aimed to explore the spatiotemporal heterogeneity in occurrence of CHIKV ZIKV outbreaks throughout Barranquilla, Colombia during 2014 2016 explored potential for clustering. Incidence data were fitted using multiple Bayesian Poisson models based on a suite explanatory variables risk factors options random effects. A best...

10.20944/preprints201902.0054.v1 preprint EN 2019-02-05
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