A5100352599- NMR spectroscopy and applications
- Advanced NMR Techniques and Applications
- Advanced MRI Techniques and Applications
- Metabolomics and Mass Spectrometry Studies
- Immunodeficiency and Autoimmune Disorders
- Advanced Battery Materials and Technologies
- Advanced Battery Technologies Research
- Animal Genetics and Reproduction
- Neutropenia and Cancer Infections
- Blood disorders and treatments
- Genetic Mapping and Diversity in Plants and Animals
- Advancements in Battery Materials
- Bone and Dental Protein Studies
- Cell Adhesion Molecules Research
- Chromosomal and Genetic Variations
- Pediatric health and respiratory diseases
- Seismic Imaging and Inversion Techniques
- Epigenetics and DNA Methylation
- Microfluidic and Bio-sensing Technologies
- Genetic Syndromes and Imprinting
- Cellular Mechanics and Interactions
- Urinary and Genital Oncology Studies
- Estrogen and related hormone effects
- Bladder and Urothelial Cancer Treatments
- Genetic and phenotypic traits in livestock
Chongqing Medical University
2010-2024
Children's Hospital of Chongqing Medical University
2010-2024
Xiamen University
2011-2024
China International Science and Technology Cooperation
2024
First Affiliated Hospital of Xiamen University
2023
Fujian Medical University
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2021
Weizmann Institute of Science
2014
Institute of Oceanology
2014
Beijing Chao-Yang Hospital
2013
Abstract The (electro)chemical reactions between Li 1.3 Al 0.3 Ti 1.7 (PO 4 ) 3 (LATP) solid‐state electrolyte and lithium metal plague the practical applications of LATP. A commonly used strategy to tackle this issue is construct an ionic conductor layer stabilize Li/LATP interface. Herein, it demonstrated that electronic interlayer (Al or Ag) can also greatly enhance interfacial stability Li/LATP. To unveil origin enhanced stability, a series techniques, including in situ electron optical...
NMR spectroscopy is a commonly used technique for metabolite analyses. Due to the observed macroscopic magnetic susceptibility in biological tissues, current acquisitions measurements of tissues are generally performed on tissue extracts using liquid or magic-angle spinning techniques. In this study, we propose an method achieve high-resolution J-resolved information analyses directly from intact samples. A dramatic improvement spectral resolution evident our contrastive demonstrations...
A scheme via spatially encoded intermolecular zero-quantum coherences was proposed for high-resolution 2D J-resolved spectra in inhomogeneous fields with high acquisition efficiency. Compared to a recent paper (Pelupessy et al. Science, 2009, 324, 1693–1697), the novel method can obtain chemical shifts and J multiplicity patterns directly.
To cite this article: Zhang Z‐Y, Zhao X‐D, Jiang L‐P, Liu E‐M, Cui Y‐X, Wang M, Wei H, Yu J, An Y‐F, Yang X‐Q. Clinical characteristics and molecular analysis of three Chinese children with Omenn syndrome. Pediatr Allergy Immunol 2011; 22 : 482–487. Abstract syndrome (OS) is a rare autosomal recessive genetic disorder presents symptoms severe combined immunodeficiency characterized by erythrodermia, eosinophilia, hepatosplenomegaly, lymphadenopathy, elevated serum IgE levels. OS has been...
NMR spectroscopy is a commonly used analytical technique in practical applications, and its applicability further promoted by pure chemical shift techniques based on spectral simplification for analyses. Unfortunately, magnetic field inhomogeneity caused adverse experimental conditions remains an obstacle restricting applications. In this study, we introduce new method high-resolution proton (1H) measurements inhomogeneous fields. We demonstrate that the allows one to perform analyses...
Mutations within the ELANE gene, which encodes human neutrophil elastase, are most common genetic causes of severe congenital neutropenia (SCN). No cases SCN have been previously described from a Chinese population. Herein, we describe clinical, hematologic and molecular characteristics 7 with novel mutations.Seven pediatric patients (4 males 3 females) suspected were enrolled in this study. Clinical data, peripheral blood, bone marrow immune function evaluated for SCN. genomic DNA cDNA...
Speeding up the acquisition of multidimensional nuclear magnetic resonance (NMR) spectra is an important topic in contemporary NMR, with central roles high-throughput investigations and analyses marginally stable samples. A variety fast NMR techniques have been developed, including methods based on non-uniform sampling Hadamard encoding, that overcome long times inherent to schemes fast-Fourier-transform (FFT) methods. Here, we explore potential alternative method leverages a priori...
Zhang Z‐Y, Xiao H‐Q, Jiang L‐P, Zhou Y, Zhao Q, Yu J, Liu W, Yang X‐Q, X‐D. Analysis of clinical and molecular characteristics Wiskott–Aldrich syndrome in 24 patients from 23 unrelated Chinese families. Pediatr Allergy Immunol 2010: 21: 522–532. © 2010 John Wiley & Sons A/S The data children with (WAS) families were reviewed the present study. WAS protein (WASP) expression peripheral blood mononuclear cells was examined by flow cytometry (FCM); WASP gene amplified PCR directly sequenced...
This thesis addresses a neglected aspect of bioinformatics research hemifacial microsomia (HFM). Existing stops short prediction based on big data. study combines multiple databases to explore underlying pathogenesis using bioinformatic approach.The consisted methods, included pathogenic genes analyses, protein-protein interaction network construction, functional enrichment, and mining target related miRNA, for studying HFM.Total 140 were identified as potential in the study. The networks...
A half-century quest for higher magnetic fields has been an integral part of the progress undergone in Nuclear Magnetic Resonance (NMR) study materials’ structure and dynamics. Because 2D NMR relies on systematic changes coherences’ phases as a function encoding time varied over series independent experiments, it generally cannot be applied temporally unstable fields. This precludes most methods from being used to characterize samples situated hybrid or resistive magnets that are capable...
Two-dimensional (2D) nuclear magnetic resonance (NMR) spectroscopy has been proven to be a powerful technique for chemical, biological, and medical studies. Heteronuclear single quantum correlation (HSQC) heteronuclear multiple bond (HMBC) are two frequently used 2D NMR methods. In combination with spatially encoded techniques, spectrum can acquired in several seconds may applied monitoring chemical reactions. However, it is difficult obtain high-resolution spectra inhomogeneous fields....