A5104454415- melanin and skin pigmentation
- Dermatologic Treatments and Research
- Cutaneous lymphoproliferative disorders research
- Autoimmune Bullous Skin Diseases
- Cancer and Skin Lesions
- Genetic and rare skin diseases.
- Hair Growth and Disorders
- Nail Diseases and Treatments
- Skin Protection and Aging
- Skin and Cellular Biology Research
- Dermatological and Skeletal Disorders
- Systemic Sclerosis and Related Diseases
- Atherosclerosis and Cardiovascular Diseases
- Retinoids in leukemia and cellular processes
- Dermatology and Skin Diseases
- Urticaria and Related Conditions
- Psoriasis: Treatment and Pathogenesis
- Oral Health Pathology and Treatment
- Cell Adhesion Molecules Research
- Nonmelanoma Skin Cancer Studies
- Autoimmune and Inflammatory Disorders
- Calpain Protease Function and Regulation
- Laser Applications in Dentistry and Medicine
- Toxin Mechanisms and Immunotoxins
- Wound Healing and Treatments
Cairo University
2016-2025
Pharos University in Alexandria
2024
Desert Research Center
2020-2022
Mansoura University
1991-2021
Ain Shams University
2017
A proposal has recently been made regarding the potential adjuvant use of platelet-rich plasma (PRP) with fractional carbon dioxide laser (FCL) for correction acne scars.To compare efficacy and safety two administration modes autologous PRP (intradermal injection (ID) topical application) after FCL that alone in treatment atrophic scars.Thirty patients were randomly divided into groups. Both underwent split-face therapy. Group 1 was administered followed by ID on one side saline other. In...
Skewing of responses towards T helper (Th) 17 and away from regulatory cells (T-regs) has been suggested to be partially involved in autoimmune diseases like vitiligo. Clarify the possible role relationship between Th17 T-regs vitiligo by measuring tissue, systemic levels interleukin (IL)-17, IL-22 Forkhead box P3. 84 non-segmental patients 80 controls were included. Vitiligo Area Scoring Index, Disease Activity stress score determined. Skin biopsies underwent immunohistochemical staining...
Summary This cross‐sectional multicenter study aimed to evaluate serum CXCL ‐10, as an activity marker for vitiligo, and compare it with other putative tissue markers. Serum ‐10 was compared interferon gamma ( IFN ‐γ), interleukin 6 IL ‐6), ‐17 using ELISA in 55 non‐segmental vitiligo patients (30 active 25 stable) 30 healthy controls. Marginal skin biopsy taken immunohistochemical evaluation of CD 8+T cells ‐10+ve cells. levels ‐17, ‐6 were elevated all controls p < .05). All...
Ablative fractional erbium-doped yttrium aluminum garnet (Er:YAG) laser and microneedling have been popularized in recent years their effectiveness side effects individually reported. No previous study, however, has directly compared the efficacy safety between 2 different treatments.To compare of ablative Er:YAG for treatment atrophic acne scars.Thirty patients with scars were randomly treated a split-face manner on one other side. All received 5 treatments 1-month interval. Objective...
BACKGROUND Novel and promising results in acne treatment with infrared lasers have been reported. The 1,550-nm erbium glass laser is one of the that may be useful acne. OBJECTIVE aim this study was to evaluate efficacy an active effect type on sebaceous glands. PATIENTS AND METHODS Twenty-four patients lesions were treated using (30–40 mJ) fractional laser. Every patient received 4 sessions a 2-week interval. Follow-up done every 3 months for 1 year. image analyzer computer system used...
Introduction: Recently, laser treatment for hair loss has become very popular. Laser-assisted drug delivery (LAD) is an evolving technology with potentially broad clinical applications. This work aims at inspecting the effect of fractional carbon dioxide (CO 2 ) on improving minoxidil in patients androgenetic alopecia and detecting role CO its treatment. Methods: We enrolled 45 Egyptians male (MAGA); grading was assessed based Norwood-Hamilton classification. The were divided into 3 groups:...
Endophytic bacteria are those that colonise the internal tissues of plant without negative impact on health. This work aims to isolate endophytic colonising Triticum vulgare and Phragmites australis evaluate their compatibility as biostimulants maize. Three six obtained isolates were selected upon surpassing ability stimulate growth maize seedlings (maximum 18% increase in germination 2.4-fold number lateral roots). These molecularly identified Klebsiella MK2R2, Bacillus B2L2 Enterobacter...
NB-UVB has long been the vitiligo management pillar with capability of achieving main treatment outcomes; repigmentation and stabilization. Its stabilizing effect in dark skin debatable. However, randomized controlled trials regarding ability to control disease activity are lacking.To assess comparison systemic corticosteroids, mainstay stabilization, photo-types (III-V).This is a multicenter, placebo-controlled, randomized, prospective study. Eighty patients active nonsegmental (NSV)...
Ultrasound scanning is becoming an important diagnostic tool in dermatology. The major advantages of this technique are its non invasive non-ionizing nature and relatively low cost. We aimed to evaluate the accuracy ultrasound biomicroscopy (UBM) diagnosis eight skin disorders namely, morphea, keloid, lichen planus, chronic eczema, psoriasis, port wine stain, seborrheic keratosis, photo-aged skin, through correlation findings with clinical pathological assessment. Fifty seven patients above...
Background: Identification is a major problem facing forensic practitioners, DNA and finger prints are highly useful but sometimes aren't easily collected from the crime scene. Lip print could be in this field being unique to each individual. Aim: The current study aimed at detecting frequency gender relation of lip pattern an Egyptian sample. Methodology: Samples were on white copy paper, divided into four quadrants then examined with magnifying lens for distribution. Results: showed that...
Both types of Ultraviolet (UV), UVB (290–320 nm) and UVA (320–400 nm), produce increased pigmentation or tanning. However, no evaluation alone in the treatment vitiligo has been reported. Therefore, it was purpose this work to study pigmentogenic effect (5 15 J/cm 2 ) vitiligo. The included 20 randomly selected patients with involving more than 30% body surface area a bilateral/symmetrical distribution. They were equally divided into two groups each 10 patients. All received three weekly...
Conventional therapy of extensive psoriasis is effective but has complications. Biologics are safer expensive.To assess the efficacy sulfasalazine and pentoxifylline, which have TNF antagonizing anti-proliferative action in treatment psoriasis.In this randomized controlled trial, 32 patients with were divided into four groups: group A received sulfasalazine; B pentoxifylline; C both drugs; D methotrexate. The Psoriasis Area Severity Index (PASI) score was done at weeks 0, 2, 4, 6 8.A...
Psoriasis vulgaris (PV) is characterized by keratinocyte hyperproliferation. Altered expression of cell-cycle regulatory genes involved in the cyclin D1 ⁄ p16 INK4-pRb pathway may contribute to this epidermal hyperproliferation.To assess and psoriasis, evaluate effect phototherapy on their expression.The study population comprised 25 patients with PV 10 healthy controls. Patients were treated 24 sessions either narrowband ultraviolet (UV) B or psoralen UVA. Skin biopsies taken from affected...
Background Vitamin D has been considered a key player in various malignancies including cutaneous cancers. To date, mycosis fungoides (MF) the least studied relation to vitamin D. Furthermore, receptor (VDR) single nucleotide polymorphisms (SNPs) have not tackled before context of MF, despite their incrimination numerous diseases. Aim study assess role MF by measuring its serum level, and studying VDR SNPs (TaqI, BsmI, FokI) different stages MF. Patients Methods 48 patients with 45 healthy...
Basaloid follicular hamartoma (BFH) is a unique benign characterized by variable clinical presentations, identical histologic features and possible associations with numerous disorders. may be hereditary or acquired. Hereditary cases either generalized unilateral nevoid. Although the forms are usually associated systemic manifestations, such as myasthenia gravis, 2 it occasionally present without internal On other hand, acquired of BFH in form localized solitary forms. Herein we four BFH,...
No effective treatment has been found for epidermolysis bullosa dystrophica (EBD).To evaluate the efficacy and safety mycophenolate mofetil (MMF) in treating EBD.This randomized controlled double-blinded study included 35 patients with severe generalized EBD. Patients were randomly divided into two groups: group I (18 patients) received cyclosporine therapy (5 mg/kg/day) II (17 MMF (500-1500 mg/day). Clinical assessment was made weekly 3 months from start of treatment. assessed by measuring...
Summary Background Vitiligo is an acquired pigmentary disorder that affects between 1% and 2% of the general population. Phototherapy remains cornerstone treatment, with NB‐UVB being most frequently used. BB‐UVA can be a plausible alternative for darker population; skin photo type III IV . Patients Methods The study was prospective, randomized, controlled, single‐blinded clinical trial, conducted on 40 patients bilateral symmetrical vitiligo. were randomly divided into two equal groups;...